scholarly journals The Light Skin Allele of SLC24A5 in South Asians and Europeans Shares Identity by Descent

PLoS Genetics ◽  
2013 ◽  
Vol 9 (11) ◽  
pp. e1003912 ◽  
Author(s):  
Chandana Basu Mallick ◽  
Florin Mircea Iliescu ◽  
Märt Möls ◽  
Sarah Hill ◽  
Rakesh Tamang ◽  
...  
Keyword(s):  
South Asians ◽  
Identity By Descent ◽  
Light Skin

scholarly journals Most frequent South Asian haplotypes of ACE2 share identity by descent with East Eurasian populations

2020 ◽  
Author(s):  
Anshika Srivasta ◽  
Rudra Kumar Pandey ◽  
Pramod Kumar ◽  
Avinash Arvind Rasalkar ◽  
Rakesh Tamang ◽  
...  
Keyword(s):  
South Asian ◽  
South Asians ◽  
Host Susceptibility ◽  
The Novel ◽  
The West ◽  
Identity By Descent ◽  
Southeast Asians ◽  
Genome Data ◽  
Unique Event ◽  
Novel Coronavirus

Abstract It was shown that the human ACE2 is the receptor of recent coronavirus SARS-CoV-2 and variation in this gene may affect the susceptibility of a population. Therefore, we have analysed whole genome data of World populations focusing South Asia. Genetically, South Asians are more related with the West Eurasian populations rather than East Eurasians. Whereas, for this gene, unexpectedly South Asians are more closer to East Eurasians rather than West Eurasians. The phylogenetic analysis suggested that the majority of South Asian haplotypes are shared with the East Eurasians in the background of two unique event polymorphisms which are responsible for this attraction. The second SNP rs2285666 has marked difference among South Asian vs European/American. Hence, it is highly likely that among the South Asians, the host susceptibility to the novel coronavirus SARS-CoV-2 will be more similar to East/Southeast Asians rather than the Europeans.

Acceptance of Cosmetic Surgery Among British Female University Students

2012 ◽  
Vol 17 (1) ◽  
pp. 55-62 ◽  
Author(s):  
Viren Swami ◽  
Angela Nogueira Campana ◽  
Rebecca Coles
Keyword(s):  
University Students ◽  
Ethnic Differences ◽  
Cosmetic Surgery ◽  
South Asians ◽  
Ethnically Diverse ◽  
Self Esteem ◽  
Demographic Variables ◽  
Lower Body ◽  
Body Appreciation ◽  
African Caribbean

Although patients of cosmetic surgery are increasingly ethnically diverse, previous studies have not examined ethnic differences in attitudinal dispositions toward cosmetic surgery. In the present study, 751 British female university students from three ethnic groups (Caucasians, South Asians, and African Caribbeans) completed measures of acceptance of cosmetic surgery, body appreciation, self-esteem, and demographic variables. Initial between-group analyses showed that Caucasians had lower body appreciation and self-esteem than Asian and African Caribbean participants. Importantly, Caucasians had higher acceptance of cosmetic surgery than their ethnic minority counterparts, even after controlling for body appreciation, self-esteem, age, and body mass index. Further analyses showed that ethnicity accounted for a small proportion of the variance in acceptance of cosmetic surgery, with body appreciation and self-esteem emerging as stronger predictors. Possible reasons for ethnic differences in acceptance of cosmetic surgery are discussed in Conclusion.

Impaired Beta-Cell Compensation and Glucose Effectiveness in Insulin Resistant, Nondiabetic South Asians

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 251-LB
Author(s):  
CAROLINE SEDMAK ◽  
SHIVRAJ GREWAL ◽  
SHANAZ SIKDER ◽  
MICHAEL GLICKSMAN ◽  
REED G. MSZAR ◽  
...  
Keyword(s):  
Beta Cell ◽  
South Asians ◽  
Glucose Effectiveness ◽  
Insulin Resistant ◽  
Beta Cell Compensation

Social and lifestyle interventions for preventing low birthweight in South Asians

2007 ◽  
Author(s):  
Jane West ◽  
John J Wright ◽  
Derek J Tuffnell ◽  
Diane Farrar ◽  
Ian Watt
Keyword(s):  
Low Birthweight ◽  
South Asians ◽  
Lifestyle Interventions

scholarly journals Darker shades of “fairness” in India: Male attractiveness and colorism in commercials

2020 ◽  
Vol 6 (1) ◽  
pp. 225-248
Author(s):  
Sayantan Mukherjee
Keyword(s):  
Critical Discourse Analysis ◽  
Skin Tone ◽  
Indian Society ◽  
Primary Data ◽  
Television Commercials ◽  
Multimodal Analysis ◽  
Light Skin ◽  
Indian Men ◽  
Skin Lightening

AbstractThe skin-lightening products for men in India and their mode of advertising have been shaping the concept of attractiveness for Indian men by portraying lighter skin tone as the most fundamental quality of being attractive, always desirable, and successful. Although women’s skin-lightening products in India have received attention by a few scholars lately, men’s products are still underresearched. Hence, this study aims to investigate the issue of colorism augmented by television commercials for men’s “fairness” (light skin tone) products in India. The primary data for this study are six Hindi television commercials for men’s skin-lightening products which were broadcast from 2005 to 2015 and were available on YouTube during data collection. The commercials are by one popular brand, Emami Fair and Handsome. The target commercials are significant for their categorical distinction in directness as well as for their nature of storytelling that helps facilitate the discourse of colorism itself. The methodology is a combination of multimodal analysis, critical discourse analysis, and advertisement analysis. The overall goal of this study is to bring visibility to this subtle and multilayered problem of colorism in Indian society which is being reinforced by the skin-lightening products for men.

scholarly journals Plasma protein expression profiles, cardiovascular disease, and religious struggles among South Asians in the MASALA study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Long H. Ngo ◽  
M. Austin Argentieri ◽  
Simon T. Dillon ◽  
Blake Victor Kent ◽  
Alka M. Kanaya ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Plasma Protein ◽  
Expression Profiles ◽  
South Asians ◽  
Predictive Biomarkers ◽  
Information Criteria ◽  
Blood Protein ◽  
Complement Factor ◽  
Factor B ◽  
Complement Factor B

AbstractBlood protein concentrations are clinically useful, predictive biomarkers of cardiovascular disease (CVD). Despite a higher burden of CVD among U.S. South Asians, no CVD-related proteomics study has been conducted in this sub-population. The aim of this study is to investigate the associations between plasma protein levels and CVD incidence, and to assess the potential influence of religiosity/spirituality (R/S) on significant protein-CVD associations, in South Asians from the MASALA Study. We used a nested case–control design of 50 participants with incident CVD and 50 sex- and age-matched controls. Plasma samples were analyzed by SOMAscan for expression of 1305 proteins. Multivariable logistic regression models and model selection using Akaike Information Criteria were performed on the proteins and clinical covariates, with further effect modification analyses conducted to assess the influence of R/S measures on significant associations between proteins and incident CVD events. We identified 36 proteins that were significantly expressed differentially among CVD cases compared to matched controls. These proteins are involved in immune cell recruitment, atherosclerosis, endothelial cell differentiation, and vascularization. A final multivariable model found three proteins (Contactin-5 [CNTN5], Low affinity immunoglobulin gamma Fc region receptor II-a [FCGR2A], and Complement factor B [CFB]) associated with incident CVD after adjustment for diabetes (AUC = 0.82). Religious struggles that exacerbate the adverse impact of stressful life events, significantly modified the effect of Contactin-5 and Complement factor B on risk of CVD. Our research is this first assessment of the relationship between protein concentrations and risk of CVD in a South Asian sample. Further research is needed to understand patterns of proteomic profiles across diverse ethnic communities, and the influence of resources for resiliency on proteomic signatures and ultimately, risk of CVD.

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