Psychological and pharmacological interventions for posttraumatic stress disorder and comorbid mental health problems following complex traumatic events: Systematic review and component network meta-analysis

Objective. The aims of this systematic review were to integrate the research on posttraumatic stress (PTS) and posttraumatic stress disorder (PTSD) after termination of pregnancy (TOP), miscarriage, perinatal death, stillbirth, neonatal death, and failed in vitro fertilisation (IVF).Methods. Electronic databases (AMED, British Nursing Index, CINAHL, MEDLINE, SPORTDiscus, PsycINFO, PubMEd, ScienceDirect) were searched for articles using PRISMA guidelines.Results. Data from 48 studies were included. Quality of the research was generally good. PTS/PTSD has been investigated in TOP and miscarriage more than perinatal loss, stillbirth, and neonatal death. In all reproductive losses and TOPs, the prevalence of PTS was greater than PTSD, both decreased over time, and longer gestational age is associated with higher levels of PTS/PTSD. Women have generally reported more PTS or PTSD than men. Sociodemographic characteristics (e.g., younger age, lower education, and history of previous traumas or mental health problems) and psychsocial factors influence PTS and PTSD after TOP and reproductive loss.Conclusions. This systematic review is the first to investigate PTS/PTSD after reproductive loss. Patients with advanced pregnancies, a history of previous traumas, mental health problems, and adverse psychosocial profiles should be considered as high risk for developing PTS or PTSD following reproductive loss.

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Prevalence of, Risk Factors for, and Consequences of Posttraumatic Stress Disorder and Other Mental Health Problems in Military Populations Deployed to Iraq and Afghanistan

Current Psychiatry Reports ◽

10.1007/s11920-015-0575-z ◽

2015 ◽

Vol 17 (5) ◽

Cited By ~ 74

Author(s):

Rajeev Ramchand ◽

Rena Rudavsky ◽

Sean Grant ◽

Terri Tanielian ◽

Lisa Jaycox

Keyword(s):

Mental Health ◽

Risk Factors ◽

Posttraumatic Stress Disorder ◽

Posttraumatic Stress ◽

Stress Disorder ◽

Mental Health Problems ◽

Health Problems ◽

Military Populations

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Relationships Between Interpersonal Trauma, Symptoms of Posttraumatic Stress Disorder, and Other Mental Health Problems in Girls in Compulsory Residential Care

Journal of Traumatic Stress ◽

10.1002/jts.21831 ◽

2013 ◽

Vol 26 (4) ◽

pp. 526-529 ◽

Cited By ~ 10

Author(s):

Laura E. W. Leenarts ◽

Robert R. J. M. Vermeiren ◽

Peter M. van de Ven ◽

Henny P. B. Lodewijks ◽

Theo A. H. Doreleijers ◽

...

Keyword(s):

Mental Health ◽

Posttraumatic Stress Disorder ◽

Posttraumatic Stress ◽

Residential Care ◽

Stress Disorder ◽

Mental Health Problems ◽

Health Problems ◽

Interpersonal Trauma ◽

Trauma Symptoms

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Prevalence and Risk Factors of Mental Health Symptoms and Suicidal Behavior Among University Students in Wuhan, China During the COVID-19 Pandemic

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.695017 ◽

2021 ◽

Vol 12 ◽

Author(s):

Yingying Xu ◽

Sizhen Su ◽

Zhendong Jiang ◽

Suihuai Guo ◽

Qingdong Lu ◽

...

Keyword(s):

Mental Health ◽

Risk Factors ◽

Posttraumatic Stress Disorder ◽

University Students ◽

Posttraumatic Stress ◽

Suicidal Behavior ◽

Stress Disorder ◽

Mental Health Problems ◽

Health Problems ◽

Symptoms Of Depression

Background: University students who are exposed to coronavirus disease 2019 (COVID-19) could be mentally distressed. We aimed to evaluate the pattern and risk factors of mental health and suicidal behavior among students who experienced long-term school closure due to the COVID-19 pandemic.Methods: This large-sample, cross-sectional, online survey was conducted from June 29, 2020, to July 18, 2020. Eleven thousand two hundred fifty four participants were recruited from 30 universities located in Wuhan, Hubei Province, China. The prevalence of symptoms of depression, anxiety, insomnia, and posttraumatic stress disorder (PTSD) and suicidal behavior was evaluated using the Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Insomnia Severity Index, Posttraumatic Stress Disorder Checklist for DSM-5, and questions about suicidal ideation and attempts, respectively. Logistic regression was used to explore risk factors for mental health problems and suicidal behavior.Results: The prevalence of mental health problems was 41.5% for depressive symptoms, 32.6% for anxiety symptoms, 35.0% for insomnia symptoms, 8.5% for PTSD symptoms, and 2.0% for suicidal behavior. Participants with high stress during the pandemic were at higher risk of symptoms of depression [adjusted odds ratio (OR) = 1.67, 95% confidence interval (CI) = 1.43–1.95, p < 0.01), anxiety (adjusted OR = 1.90, 95% CI = 1.63–2.23, p < 0.01), insomnia (adjusted OR = 1.64, 95% CI = 1.44–1.87, p < 0.01), PTSD (adjusted OR = 1.71, 95% CI = 1.38–2.11, p < 0.01) and suicidal behavior (adjusted OR = 3.51, 95% CI = 2.28–5.40, p < 0.01). Distant relationship with parents, changes in lifestyle and alcohol use during the pandemic were associated with higher risk of mental health symptoms and suicidal behavior, whereas regular physical exercise reduced the risk of mental health problems.Conclusions: The psychological symptoms and suicidal behavior were relatively high among students who attended university in Wuhan, China after 6 months of the COVID-19 outbreak in China. Comprehensive mental health services and suicide prevention strategies are essential for university students during the COVID-19 pandemic.

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