Constitutive Activity among Orphan Class-A G Protein Coupled Receptors

PLoS ONE ◽

10.1371/journal.pone.0138463 ◽

2015 ◽

Vol 10 (9) ◽

pp. e0138463 ◽

Author(s):

Adam L. Martin ◽

Michael A. Steurer ◽

Robert S. Aronstam

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

Constitutive Activity ◽

Class A ◽

G Protein Coupled

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FoldGPCR: Structure prediction protocol for the transmembrane domain of G protein-coupled receptors from class A

Proteins Structure Function and Bioinformatics ◽

10.1002/prot.22731 ◽

2010 ◽

Vol 78 (10) ◽

pp. 2189-2201 ◽

Author(s):

Mayako Michino ◽

Jianhan Chen ◽

Raymond C. Stevens ◽

Charles L. Brooks

Keyword(s):

G Protein ◽

Structure Prediction ◽

Transmembrane Domain ◽

G Protein Coupled Receptors ◽

Class A ◽

G Protein Coupled

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Frontispiece: Universality of the Sodium Ion Binding Mechanism in Class A G-Protein-Coupled Receptors

Angewandte Chemie International Edition ◽

10.1002/anie.201881261 ◽

2018 ◽

Vol 57 (12) ◽

Author(s):

Balaji Selvam ◽

Zahra Shamsi ◽

Diwakar Shukla

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

Ion Binding ◽

Binding Mechanism ◽

Class A ◽

G Protein Coupled

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Homology Modeling of Class A G-Protein-Coupled Receptors in the Age of the Structure Boom

Methods in Molecular Biology - Computational Design of Membrane Proteins ◽

10.1007/978-1-0716-1468-6_5 ◽

2021 ◽

pp. 73-97

Author(s):

Asma Tiss ◽

Rym Ben Boubaker ◽

Daniel Henrion ◽

Hajer Guissouma ◽

Marie Chabbert

Keyword(s):

Homology Modeling ◽

G Protein ◽

G Protein Coupled Receptors ◽

Class A ◽

G Protein Coupled

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Importance of protein dynamics in the structure-based drug discovery of class A G protein-coupled receptors (GPCRs)

Current Opinion in Structural Biology ◽

10.1016/j.sbi.2019.03.015 ◽

2019 ◽

Vol 55 ◽

pp. 147-153 ◽

Author(s):

Yoonji Lee ◽

Raudah Lazim ◽

Stephani Joy Y Macalino ◽

Sun Choi

Keyword(s):

Drug Discovery ◽

Protein Dynamics ◽

G Protein ◽

G Protein Coupled Receptors ◽

Class A ◽

G Protein Coupled

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Universality of the Sodium Ion Binding Mechanism in Class A G-Protein-Coupled Receptors

Angewandte Chemie ◽

10.1002/ange.201708889 ◽

2018 ◽

Vol 130 (12) ◽

pp. 3102-3107 ◽

Author(s):

Balaji Selvam ◽

Zahra Shamsi ◽

Diwakar Shukla

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

Ion Binding ◽

Binding Mechanism ◽

Class A ◽

G Protein Coupled

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G protein-coupled receptors of class A harness the energy of membrane potential to increase their sensitivity and selectivity

Biochimica et Biophysica Acta (BBA) - Biomembranes ◽

10.1016/j.bbamem.2019.183051 ◽

2019 ◽

Vol 1861 (12) ◽

pp. 183051 ◽

Author(s):

Daria N. Shalaeva ◽

Dmitry A. Cherepanov ◽

Michael Y. Galperin ◽

Gert Vriend ◽

Armen Y. Mulkidjanian

Keyword(s):

Membrane Potential ◽

G Protein ◽

G Protein Coupled Receptors ◽

Class A ◽

Sensitivity And Selectivity ◽

G Protein Coupled

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An Indel in Transmembrane Helix 2 Helps to Trace the Molecular Evolution of Class A G-Protein-Coupled Receptors

Journal of Molecular Evolution ◽

10.1007/s00239-009-9214-9 ◽

2009 ◽

Vol 68 (5) ◽

pp. 475-489 ◽

Author(s):

Julie Devillé ◽

Julien Rey ◽

Marie Chabbert

Keyword(s):

Molecular Evolution ◽

G Protein ◽

Transmembrane Helix ◽

G Protein Coupled Receptors ◽

Class A ◽

G Protein Coupled

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Constitutive Activity and Inverse Agonists of G Protein-Coupled Receptors: a Current Perspective: TABLE 1

Molecular Pharmacology ◽

10.1124/mol.64.6.1271 ◽

2003 ◽

Vol 64 (6) ◽

pp. 1271-1276 ◽

Author(s):

Graeme Milligan

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

Constitutive Activity ◽

Inverse Agonists ◽

Current Perspective ◽

G Protein Coupled ◽

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GPCRtm: An amino acid substitution matrix for the transmembrane region of class A G Protein-Coupled Receptors

BMC Bioinformatics ◽

10.1186/s12859-015-0639-4 ◽

2015 ◽

Vol 16 (1) ◽

Author(s):

Santiago Rios ◽

Marta F. Fernandez ◽

Gianluigi Caltabiano ◽

Mercedes Campillo ◽

Leonardo Pardo ◽

...

Keyword(s):

G Protein ◽

Amino Acid Substitution ◽

G Protein Coupled Receptors ◽

Substitution Matrix ◽

Transmembrane Region ◽

Class A ◽

Amino Acid Substitution Matrix ◽

G Protein Coupled

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Chemical Tools for Studying Lipid-Binding Class A G Protein–Coupled Receptors

Pharmacological Reviews ◽

10.1124/pr.116.013243 ◽

2017 ◽

Vol 69 (3) ◽

pp. 316-353 ◽

Author(s):

Anna Cooper ◽

Sameek Singh ◽

Sarah Hook ◽

Joel D. A. Tyndall ◽

Andrea J. Vernall

Keyword(s):

G Protein ◽

Lipid Binding ◽

G Protein Coupled Receptors ◽

Class A ◽

Chemical Tools ◽

G Protein Coupled

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