The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Preserves Endothelial Function in Mesenteric Arteries from Type 1 Diabetic Rats without Decreasing Plasma Glucose

PLoS ONE ◽

10.1371/journal.pone.0143941 ◽

2015 ◽

Vol 10 (11) ◽

pp. e0143941 ◽

Author(s):

Salheen M. Salheen ◽

Usha Panchapakesan ◽

Carol A. Pollock ◽

Owen L. Woodman

Keyword(s):

Endothelial Function ◽

Plasma Glucose ◽

Dipeptidyl Peptidase ◽

Diabetic Rats ◽

Mesenteric Arteries ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

Download Full-text

Immunohistochemical, apoptotic and biochemical changes by dipeptidyl peptidase-4 inhibitor-sitagliptin in type-2 diabetic rats

Pharmacological Reports ◽

10.1016/j.pharep.2015.01.010 ◽

2015 ◽

Vol 67 (5) ◽

pp. 846-853 ◽

Author(s):

Sezin Karabulut ◽

Zeynep Mine Coskun ◽

Sema Bolkent

Keyword(s):

Dipeptidyl Peptidase ◽

Diabetic Rats ◽

Biochemical Changes ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Type 2 Diabetic

Download Full-text

Potentiation of endothelium-dependent vasorelaxation of mesenteric arteries from spontaneously hypertensive rats by gemigliptin, a dipeptidyl peptidase-4 inhibitor class of anti-diabetic drug

Korean Journal of Physiology and Pharmacology ◽

10.4196/kjpp.2018.22.6.713 ◽

2018 ◽

Vol 22 (6) ◽

pp. 713 ◽

Author(s):

Hae Jin Kim ◽

Eun Bok Baek ◽

Sung Joon Kim

Keyword(s):

Spontaneously Hypertensive Rats ◽

Dipeptidyl Peptidase ◽

Mesenteric Arteries ◽

Hypertensive Rats ◽

Spontaneously Hypertensive ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

Download Full-text

Combined treatment with dipeptidyl peptidase-4 inhibitor (sitagliptin) and angiotensin-II type 1 receptor blocker (losartan) suppresses progression in a non-diabetic rat model of steatohepatitis

Hepatology Research ◽

10.1111/hepr.12860 ◽

2017 ◽

Vol 47 (12) ◽

pp. 1317-1328 ◽

Author(s):

Yasushi Okura ◽

Tadashi Namisaki ◽

Kei Moriya ◽

Mitsuteru Kitade ◽

Kosuke Takeda ◽

...

Keyword(s):

Angiotensin Ii ◽

Rat Model ◽

Combined Treatment ◽

Dipeptidyl Peptidase ◽

Receptor Blocker ◽

Diabetic Rat ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Diabetic Rat Model

Download Full-text

The Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Improves Vascular Endothelial Function in Type 2 Diabetes

Journal of Korean Medical Science ◽

10.3346/jkms.2012.27.11.1364 ◽

2012 ◽

Vol 27 (11) ◽

pp. 1364 ◽

Author(s):

Yoshiaki Kubota ◽

Masaaki Miyamoto ◽

Gen Takagi ◽

Takeshi Ikeda ◽

Sonoko Kirinoki-Ichikawa ◽

...

Keyword(s):

Type 2 Diabetes ◽

Endothelial Function ◽

Dipeptidyl Peptidase ◽

Vascular Endothelial ◽

Vascular Endothelial Function ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

Download Full-text

Dipeptidyl Peptidase 4 Inhibitor Sitagliptin Protects Endothelial Function in Hypertension Through a Glucagon–Like Peptide 1–Dependent Mechanism

Hypertension ◽

10.1161/hypertensionaha.112.195115 ◽

2012 ◽

Vol 60 (3) ◽

pp. 833-841 ◽

Author(s):

Limei Liu ◽

Jian Liu ◽

Wing Tak Wong ◽

Xiao Yu Tian ◽

Chi Wai Lau ◽

...

Keyword(s):

Endothelial Function ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1 ◽

Dependent Mechanism

Download Full-text

Vildagliptin, a dipeptidyl peptidase-4 inhibitor, attenuated endothelial dysfunction through miRNAs in diabetic rats

Archives of Medical Science ◽

10.5114/aoms.2019.86609 ◽

2019 ◽

Author(s):

Qian Zhang ◽

Xinhua Xiao ◽

Jia Zheng ◽

Ming Li ◽

Miao Yu ◽

...

Keyword(s):

Endothelial Dysfunction ◽

Dipeptidyl Peptidase ◽

Diabetic Rats ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

Download Full-text

Abelmoschus esculentus subfractions improved nephropathy with regulating dipeptidyl peptidase-4 and type 1 glucagon-like peptide receptor in type 2 diabetic rats

Journal of Food and Drug Analysis ◽

10.1016/j.jfda.2018.07.004 ◽

2019 ◽

Vol 27 (1) ◽

pp. 135-144 ◽

Author(s):

Chiung-Huei Peng ◽

Hsing-Chun Lin ◽

Chih-Li Lin ◽

Chau-Jong Wang ◽

Chien-Ning Huang

Keyword(s):

Dipeptidyl Peptidase ◽

Diabetic Rats ◽

Abelmoschus Esculentus ◽

Dipeptidyl Peptidase 4 ◽

Peptide Receptor ◽

Glucagon Like Peptide ◽

Type 2 Diabetic

Download Full-text

Oral therapy for type 1 diabetes mellitus using a novel immunomodulator, FTY720 (fingolimod), in combination with sitagliptin, a dipeptidyl peptidase-4 inhibitor, examined in non-obese diabetic mice

Journal of Diabetes Investigation ◽

10.1111/j.2040-1124.2012.00218.x ◽

2012 ◽

Vol 3 (5) ◽

pp. 441-448 ◽

Author(s):

Takumi Tsuji ◽

Yuya Yoshida ◽

Tetsuro Fujita ◽

Takeyuki Kohno

Keyword(s):

Diabetes Mellitus ◽

Type 1 Diabetes ◽

Type 1 Diabetes Mellitus ◽

Oral Therapy ◽

Dipeptidyl Peptidase ◽

Diabetic Mice ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

Download Full-text

Autonomic Diabetic Neuropathy Impairs Glucose and Dipeptidyl Peptidase 4 Inhibitor-Regulated Glucagon Concentration in Type 1 Diabetic Patients

Journal of Endocrinology and Metabolism ◽

10.14740/jem289w ◽

2015 ◽

Vol 5 (4) ◽

pp. 229-237 ◽

Author(s):

Emilie Lobinet ◽

Francois Reichardt ◽

Celine Garret ◽

Laurent Cazals ◽

Aurelie Waget ◽

...

Keyword(s):

Diabetic Neuropathy ◽

Dipeptidyl Peptidase ◽

Diabetic Patients ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Type 1 Diabetic Patients ◽

Glucagon Concentration

Download Full-text

In patients with type 2 diabetes the presence of Hashimoto’s thyroiditis reduces the beneficial effect of dipeptidyl peptidase–4 inhibitor on plasma glucose control

Endocrine Journal ◽

10.1507/endocrj.ej20-0620 ◽

2021 ◽

Author(s):

Takuya Watanabe ◽

Yuichi Temma ◽

Junichi Okada ◽

Eijiro Yamada ◽

Tsugumichi Saito ◽

...

Keyword(s):

Type 2 Diabetes ◽

Beneficial Effect ◽

Plasma Glucose ◽

Glucose Control ◽

Hashimoto’S Thyroiditis ◽

Dipeptidyl Peptidase ◽

Hashimoto's Thyroiditis ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

Download Full-text