scholarly journals Diagnostic accuracy and prognostic applications of CYFRA 21-1 in head and neck cancer: A systematic review and meta-analysis

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0216561 ◽  
Author(s):  
Lihui Liu ◽  
Wenji Xie ◽  
Pei Xue ◽  
Zixuan Wei ◽  
Xiao Liang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Diagnostic Accuracy ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis

Diagnostic Accuracy of Follow-Up FDG PET or PET/CT in Patients With Head and Neck Cancer After Definitive Treatment: A Systematic Review and Meta-Analysis

2015 ◽  
Vol 205 (3) ◽  
pp. 629-639 ◽  
Author(s):  
Sara Sheikhbahaei ◽  
Mehdi Taghipour ◽  
Rubina Ahmad ◽  
Carole Fakhry ◽  
Ana P. Kiess ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Diagnostic Accuracy ◽  
Head And Neck ◽  
Neck Cancer ◽  
Fdg Pet ◽  
Meta Analysis ◽  
Definitive Treatment ◽  
Pet Ct

Systematic Review and Meta-Analysis of Diagnostic Accuracy of 18F-FDG PET in Suspected Recurrent Head and Neck Cancer

2008 ◽  
Vol 59 (4) ◽  
pp. 190-197 ◽  
Author(s):  
Juan Antonio Pasamontes Pingarrón ◽  
María Nieves Cabrera Martín ◽  
Roberto Carlos Delgado Bolton ◽  
Cristina Fernández Pérez ◽  
José Luis Carreras Delgado ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Diagnostic Accuracy ◽  
Head And Neck ◽  
Neck Cancer ◽  
Fdg Pet ◽  
Meta Analysis ◽  
18F Fdg ◽  
Recurrent Head

Diagnostic accuracy of serum biomarkers for head and neck cancer: A systematic review and meta-analysis

2016 ◽  
Vol 101 ◽  
pp. 93-118 ◽  
Author(s):  
Eliete Neves Silva Guerra ◽  
Daniela Fortunato Rêgo ◽  
Silvia Taveira Elias ◽  
Ricardo D. Coletta ◽  
Luis André Mendonça Mezzomo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Diagnostic Accuracy ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Serum Biomarkers

scholarly journals Salivary DNA Methylation as an Epigenetic Biomarker for Head and Neck Cancer. Part I: A Diagnostic Accuracy Meta-Analysis

2021 ◽  
Vol 11 (6) ◽  
pp. 568
Author(s):  
Óscar Rapado-González ◽  
Cristina Martínez-Reglero ◽  
Ángel Salgado-Barreira ◽  
Laura Muinelo-Romay ◽  
Juan Muinelo-Lorenzo ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Head And Neck Cancer ◽  
Diagnostic Accuracy ◽  
Head And Neck ◽  
Likelihood Ratio ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Positive Likelihood Ratio ◽  
Epigenetic Mechanism ◽  
Cochrane Library

DNA hypermethylation is an important epigenetic mechanism for gene expression inactivation in head and neck cancer (HNC). Saliva has emerged as a novel liquid biopsy representing a potential source of biomarkers. We performed a comprehensive meta-analysis to evaluate the overall diagnostic accuracy of salivary DNA methylation for detecting HNC. PubMed EMBASE, Web of Science, LILACS, and the Cochrane Library were searched. Study quality was assessed by the Quality Assessment for Studies of Diagnostic Accuracy-2, and sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (dOR), and their corresponding 95% confidence intervals (CIs) were calculated using a bivariate random-effect meta-analysis model. Meta-regression and subgroup analyses were performed to assess heterogeneity. Eighty-four study units from 18 articles with 8368 subjects were included. The pooled sensitivity and specificity of salivary DNA methylation were 0.39 and 0.87, respectively, while PLR and NLR were 3.68 and 0.63, respectively. The overall area under the curve (AUC) was 0.81 and the dOR was 8.34. The combination of methylated genes showed higher diagnostic accuracy (AUC, 0.92 and dOR, 36.97) than individual gene analysis (AUC, 0.77 and dOR, 6.02). These findings provide evidence regarding the potential clinical application of salivary DNA methylation for HNC diagnosis.

scholarly journals Incidence of Oral Mucositis in Patients Undergoing Head and Neck Cancer Treatment: Systematic Review and Meta-Analysis

2021 ◽  
Vol 5 (1) ◽  
pp. 23
Author(s):  
Raquel Pacheco ◽  
Maria Alzira Cavacas ◽  
Paulo Mascarenhas ◽  
Pedro Oliveira ◽  
Carlos Zagalo
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Oral Health ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis ◽  
Negative Impact ◽  
Meta Analysis ◽  
Incidence Rates

This systematic review and meta-analysis aimed to assess the literature about the incidence of oral mucositis and its degrees (mild, moderate, and severe), in patients undergoing head and neck cancer treatment (radiotherapy, chemotherapy, and surgery). Addressing this issue is important since oral mucositis has a negative impact on oral health and significantly deteriorates the quality of life. Therefore, a multidisciplinary team, including dentists, should be involved in the treatment. The overall oral mucositis incidence was 89.4%. The global incidence for mild, moderate, and severe degrees were 16.8%, 34.5%, and 26.4%, respectively. The high incidence rates reported in this review point out the need for greater care in terms of the oral health of these patients.

scholarly journals Early detection of esophageal second primary tumors using Lugol chromoendoscopy in patients with head and neck cancer: A systematic review and meta‐analysis

Head & Neck ◽  
2018 ◽  
Vol 41 (4) ◽  
pp. 1122-1130 ◽  
Author(s):  
Oisín Bugter ◽  
Steffi E. M. van de Ven ◽  
Jose A. Hardillo ◽  
Marco J. Bruno ◽  
Arjun D. Koch ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Early Detection ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Second Primary ◽  
Primary Tumors ◽  
Second Primary Tumors

Volume-outcome associations in head and neck cancer treatment: A systematic review and meta-analysis

Head & Neck ◽  
2014 ◽  
Vol 36 (12) ◽  
pp. 1820-1834 ◽  
Author(s):  
Antoine Eskander ◽  
Mazin Merdad ◽  
Jonathan C. Irish ◽  
Stephen F. Hall ◽  
Patti A. Groome ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Volume Outcome

Submandibular Gland Transfer for the Prevention of Postradiation Xerostomia in Patients with Head and Neck Cancer: A Systematic Review and Meta-Analysis

ORL ◽  
2015 ◽  
Vol 77 (2) ◽  
pp. 70-86 ◽  
Author(s):  
Fanglong Wu ◽  
Shengxin Weng ◽  
Chunjie Li ◽  
Jun Sun ◽  
Longjiang Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Submandibular Gland ◽  
Neck Cancer ◽  
Meta Analysis
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