Adrenergic and Peptidergic Control of the Regulation of cAMP Efflux and Melatonin Secretion from Perifused Rat Pineal Gland

Endocrine ◽  
1998 ◽  
Vol 9 (1) ◽  
pp. 89-96 ◽  
Author(s):  
Zoltan Rekasi ◽  
Norbert Sule ◽  
Valer Csernus ◽  
Bela Mess
Keyword(s):  
Pineal Gland ◽  
Melatonin Secretion ◽  
Rat Pineal Gland

CircRNA-WNK2 acts as a ceRNA for miR-328a-3p to promote AANAT expression in the male rat pineal gland

Endocrinology ◽  
2021 ◽  
Author(s):  
Yi Zheng ◽  
Hao-Qi Wang ◽  
Hai-Xiang Guo ◽  
Heng-Li Xie ◽  
Wei-Di Zhang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Circadian Rhythm ◽  
Pineal Gland ◽  
Rat Model ◽  
Noncoding Rnas ◽  
Luciferase Reporter ◽  
Male Rat ◽  
Biological Functions ◽  
Melatonin Secretion ◽  
Rat Pineal Gland

Abstract Noncoding RNAs (ncRNAs), including miRNAs and circRNAs, which are expressed with a daily rhythm in the rat pineal gland, are associated with the regulation of melatonin secretion and other biological functions. However, the mechanisms of these molecules in the rat pineal gland are not yet fully understood. In this study, we found circR-WNK2 was highly expressed at night, which may be involved in the regulation of melatonin secretion through the ceRNA mechanism. By dual luciferase reporter, RNA pulldown, and FISH assays, we found that miR-328a-3p can target circR-WNK2 and the Aa-nat mRNA 3’UTR. Transfection experiments indicated that circR-WNK2 could competitively bind to miR-328a-3p, reduce miR-328a-3p expression, and promote Aa-nat gene expression and melatonin secretion. And by constructing an SCGx rat model, we found that ncRNAs expressed in the pineal gland was regulated by signals from the SCN. This finding supports the hypothesis that these noncoding RNAs may interact to shape the circadian rhythm through transcriptional processing in melatonin synthesis.

Circadian Variation of Cyclic AMP in the Rat Pineal Gland

1981 ◽  
Vol 36 (3) ◽  
pp. 1295-1297 ◽  
Author(s):  
Masahiko Mikuni ◽  
Yoshiro Saito ◽  
Tsukasa Koyama ◽  
Itaru Yamashita
Keyword(s):  
Cyclic Amp ◽  
Pineal Gland ◽  
Circadian Variation ◽  
Rat Pineal Gland

Daily rhythm and regulation of clock gene expression in the rat pineal gland

2004 ◽  
Vol 120 (2) ◽  
pp. 164-172 ◽  
Author(s):  
V Simonneaux ◽  
V.-J Poirel ◽  
M.-L Garidou ◽  
D Nguyen ◽  
E Diaz-Rodriguez ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pineal Gland ◽  
Clock Gene ◽  
Daily Rhythm ◽  
Clock Gene Expression ◽  
Rat Pineal Gland

Presynaptic effects of melatonin on norepinephrine release and uptake in rat pineal gland

1991 ◽  
Vol 10 (4) ◽  
pp. 165-173 ◽  
Author(s):  
Héctor E. Chuluyan ◽  
Ruth E. Rosenstein ◽  
Su Min Chang ◽  
María M. Gálvez ◽  
Daniel P. Cardinali
Keyword(s):  
Pineal Gland ◽  
Norepinephrine Release ◽  
Rat Pineal Gland

Estrogen modulation of adrenoceptor responsiveness in the female rat pineal gland: differential expression of intracellular estrogen receptors

2004 ◽  
Vol 37 (1) ◽  
pp. 26-35 ◽  
Author(s):  
Juan J. Sanchez ◽  
Pedro Abreu ◽  
Tomas Gonzalez-Hernandez ◽  
Alexis Hernandez ◽  
Luis Prieto ◽  
...  
Keyword(s):  
Pineal Gland ◽  
Estrogen Receptors ◽  
Differential Expression ◽  
Female Rat ◽  
Rat Pineal Gland

scholarly journals Pretranslational Regulation of Rhythmic Type II Iodothyronine Deiodinase Expression by β-Adrenergic Mechanism in the Rat Pineal Gland*

Endocrinology ◽  
1999 ◽  
Vol 140 (3) ◽  
pp. 1272-1278 ◽  
Author(s):  
Yuji Kamiya ◽  
Masami Murakami ◽  
Osamu Araki ◽  
Yasuhiro Hosoi ◽  
Takayuki Ogiwara ◽  
...  
Keyword(s):  
Pineal Gland ◽  
Type Ii ◽  
Iodothyronine Deiodinase ◽  
Adrenergic Mechanism ◽  
Rat Pineal Gland

Rat Pineal Gland Suppresses the Injection Stress-Reactive ACTH Outflow

1993 ◽  
Vol 25 (03) ◽  
pp. 149-151 ◽  
Author(s):  
J. Milin ◽  
K. Djakovic-Svajcer ◽  
M. Demajo
Keyword(s):  
Pineal Gland ◽  
Rat Pineal Gland
Sign in / Sign up

Export Citation Format

Share Document