We discuss the existence and uniqueness of solution to nonlinear fractional order ordinary differential equations(Dα-ρtDβ)x(t)=f(t,x(t),Dγx(t)),t∈(0,1)with boundary conditionsx(0)=x0, x(1)=x1or satisfying the initial conditionsx(0)=0, x′(0)=1, whereDαdenotes Caputo fractional derivative,ρis constant,1<α<2,and0<β+γ≤α. Schauder's fixed-point theorem was used to establish the existence of the solution. Banach contraction principle was used to show the uniqueness of the solution under certain conditions onf.