scholarly journals Gastroesophageal reflux disease with Thal fundoplication

2016 ◽  
Vol 50 (6) ◽  
pp. 371
Author(s):  
Irwan Effendi ◽  
Yusri Dianne Jurnalis ◽  
Yorva Sayoeti ◽  
Yusirwan Yusuf
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Infants And Children ◽  
Common Phenomenon ◽  
Gastric Contents ◽  
Gerd Symptoms

Gastroesophageal reflux (GER) is a common phenomenon among heathy infants, with approximately 50% of infants aged 0 to 3 months and 67% of infants aged 4 months experiencing at least one episode of vomiting per day. GER defined as regurgitation of gastric contents into the esophagus or mouth. GER typically improves through the first postnatal year, with only 5% of healthy 12 month old infants experiencing vomiting.1,2 Complicated GER or gastroesophageal reflux disease (GERD) has been reported to affect up to 8% of infants and children with GER.l,3 Antireflux procedures (ARPs) are increasingly offered to control GERD symptoms. We report a case of a baby with GERD and treated with ThaI fundoplication procedures. Fundoplication procedure is rarely performed in management of GERD, and this is the first fundoplication procedure in children with GERD at M. Djamil Hospital.

scholarly journals Efficacy and Safety of Robotic Dor Fundoplication on Severe Gastroesophageal Reflux Disease in Patients With Scleroderma

2021 ◽  
Vol 9 ◽  
pp. 232470962110512
Author(s):  
Priyadarshini Loganathan ◽  
Mahesh Gajendran ◽  
Brian Davis ◽  
Richard McCallum
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Surgical Complication ◽  
Smooth Muscles ◽  
Dor Fundoplication ◽  
High Resolution Manometry ◽  
Refractory Gerd ◽  
Significant Impairment ◽  
Gerd Symptoms

Systemic sclerosis (SSc) is a disease that affects the gastrointestinal tract resulting in its atrophy and fibrosis of smooth muscles. Approximately 80% of SSc patients develop both gastroesophageal reflux disease (GERD) and dysphagia. The nocturnal GERD can cause regurgitation and aspiration, which can further aggravate the pulmonary fibrosis from SSc. Also, their dysphagia is further worsened by performing standard Nissen fundoplication. Therefore, we aimed to investigate whether Dor fundoplication (a 180° anterior wrap) can reduce nocturnal heartburn and regurgitation without worsening dysphagia in patients with SSc and severe GERD. Five SSc patients with drug-refractory severe GERD underwent a Dor fundoplication procedure with a median follow-up of 2 years (range: 1-5 years). In all 5 patients, the preoperative high-resolution manometry showed significant impairment of esophageal motility. Patients were interviewed postoperatively to assess for nocturnal and diurnal GERD symptoms, treatment response, the status of dysphagia, and adverse effects of surgery. The average age of 5 patients was 50 years and all were females. Four of the 5 patients (80%) reported 90% improvement in both diurnal and nocturnal GERD symptoms since surgery, with no nocturnal reflux, heartburn, or regurgitation, and reports to sleep at night without requiring any more pillows or wedges. About 50% of patients reported a decrease in their proton pump inhibitor dosage after surgery compared to before surgery. No surgical complication was reported and specifically, no worsening of dysphagia. The Dor fundoplication performed for refractory GERD in SSc patients substantially decreases heartburn and regurgitation, primarily nocturnal, without affecting dysphagia, thus improving the quality of life.

scholarly journals Prevalence of Gastroesophageal Reflux Disease Symptoms in Infants and Children

2019 ◽  
Vol 68 (6) ◽  
pp. 811-817 ◽  
Author(s):  
Maartje Singendonk ◽  
Eline Goudswaard ◽  
Miranda Langendam ◽  
Michiel van Wijk ◽  
Faridi van Etten-Jamaludin ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Infants And Children ◽  
Disease Symptoms ◽  
In Infants And Children

Patient Symptoms Correlate Poorly with Objective Measures among Patients with Gastroesophageal Reflux Disease

2014 ◽  
Vol 80 (9) ◽  
pp. 901-905
Author(s):  
Salomon Levy ◽  
Margaret Plymale ◽  
Daniel L. Davenport ◽  
Oscar I. Moreno Ponte ◽  
J. Scott Roth
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Office Visit ◽  
Categorical Variables ◽  
Institutional Review Board Approval ◽  
Institutional Review ◽  
Patient Questionnaires ◽  
Patient’S Perception ◽  
Gerd Symptoms

Presentation of gastroesophageal reflux disease (GERD) varies among patients. To attempt to understand the patient's perception of the severity of their reflux symptoms, we developed a questionnaire on which patients rated symptom severity at each office visit. After receiving Institutional Review Board approval, we retrospectively reviewed patient charts of all patients seen by one surgeon for GERD symptoms and/or presence of hiatal hernia (HH) from September 2012 to April 2013. Data from patient questionnaires combined with objective findings from subsequent or prior workup and eventual operative information were recorded. A total of 144 questionnaires were reviewed from 108 patients. Frequencies were calculated for categorical variables. Patients were divided into four categories based on size of the HH on the endoscopic report; 10 patients had no HH, 15 had small HH, 20 had medium HH, and 31 patients had large HH. Size of HH was not available for three patients. Pre- and postoperative questionnaire responses were obtained for 15 patients. A combined reflux score was calculated using the median for each symptom. Patient perception of severity of symptoms does not necessarily predict presence of pathological reflux or HH nor is there a perfect combination of symptoms to predict the presence of pathological reflux or HH based on our sample. The workup of this pathology must be comprehensive, and the confirmation of reflux is imperative when the diagnosis is unclear.

scholarly journals Microbiota of the Esophagus and Stomach in Patients with Gastroesophageal Reflux Disease and Healthy Volunteers

2018 ◽  
Vol 28 (4) ◽  
pp. 36-46 ◽  
Author(s):  
D. E. Rumyantseva ◽  
A. S. Trukhmanov ◽  
A. V. Kudryavtseva ◽  
G. S. Krasnov ◽  
A. V. Paraskevova ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Healthy Volunteers ◽  
Ribosomal Rna ◽  
Reflux Disease ◽  
Relative Number ◽  
Bacterial Composition ◽  
16S Gene ◽  
Gastric Contents ◽  
Number Of Bacteria

This paper is aimed at investigating the microbiota of the esophagus and stomach in patients with gastroesophageal reflux disease (GERD) and healthy volunteers.Materials and methods.  The study included 15 patients suffering from GERD and 6 healthy volunteers. All subjects underwent sampling of esophageal and gastric contents. The study of the microbiota in the obtained samples was performed by sequencing the 16S gene of ribosomal RNA (rRNA).Results. The most common types of bacteria in the esophagus and stomach in patients with GERD and healthy volunteers are found to be Bacteroidetes, Firmicutes, Actinobacteria, Proteobacteria, Fusobacterium. By comparing the relative contents of the main types of bacteria in the esophageal mucus and gastric contents, a significant decrease in the proportion of Proteobacteria was observed in patients with GERD as compared to healthy volunteers. The decrease in the relative number of bacteria belonging to the Acetobacteraceae, Bacillaceae, Bdellovibrionaceae, Clostridiales Insertae Sedis XI, Fusobacteriaceae, Moraxellaceae, Pasteurellaceae and Rhodocyclaceae families was observed in the esophagus in patients with GERD as compared to healthy volunteers. A higher bacterial content of the Leptotrichiaceae and Veillonellaceae families was detected in the stomach of patients with GERD.Conclusions.  The obtained results indicate differences in the intraluminal microbiota of the esophagus and stomach in patients with GERD and healthy volunteers. Further study should be carried out to study the effect of changes in bacterial composition on those in the esophagus and stomach. 

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