scholarly journals Role of Computed Tomography Guided Fine-Needle Aspiration Cytology in the Study of Various Thoracic Mass Lesions

2021 ◽  
Vol 10 (18) ◽  
pp. 1269-1274
Author(s):  
Nawanita Kumari ◽  
Nidhish Kumar ◽  
Sharvani Singh ◽  
Vishal Vaibhaw

BACKGROUND Intrathoracic mass is a problem faced by the clinicians worldwide which is difficult to diagnose correctly. The mediastinum although a small anatomic compartment, the pathologic processes found in it are diverse. Imaging techniques are very helpful for detection and diagnosing these lesions. The current study was conducted for assessing the diagnostic accuracy and efficacy of computed tomography (CT) guided fine-needle aspiration cytology (FNAC) in the evaluation of various thoracic mass lesions and also to compare the histopathological findings of CT guided FNAC for evaluation of the type of thoracic lesions & its prognosis. METHODS Data for the study was collected from 50 patients referred to the Department of Pathology, in a tertiary care hospital for 16 months from December 2015 to March 2017. RESULTS Among 50 patients with intrathoracic mass, there were 37 men (74 %) and 13 women (26 %). The age of patients with intrathoracic masses in this study varied from 31 to 80 years. The mean age was 55 years. Thirty-two patients were found to have malignant tumours and 18 cases were of benign aetiology. The highest frequency of cases in this study were of adenocarcinoma followed by squamous cell carcinoma. CONCLUSIONS Computed tomography (CT) guided fine-needle aspiration cytology (FNAC) is a cost effective, simple, safe, highly sensitive & specific procedure with high diagnostic accuracy in the diagnosis of intrathoracic mass lesions. It has few complications, rarely requiring active management. KEY WORDS Intrathoracic Mass, Fine-Needle Aspiration Cytology, Pneumothorax, Pneumonectomy, Thoracic Mass Lesions

1970 ◽  
Vol 1 (1) ◽  
pp. 17-21 ◽  
Author(s):  
S Parahjuli ◽  
A Tuladhar ◽  
RB Basnet

Background: Ultrasonography and computed tomography guided fine needle aspiration cytology has an important role in diagnosing intraabdominal and intrathoracic mass lesions. It has an accuracy of 70-90%, depending on the site under evaluation. Materials and Methods: This retrospective study was done in the Department of Pathology, Kathmandu Model Hospital, between June 2006 and November 2010. The study included 53 abdominal and 47 thoracic masses. The cytological diagnosis was correlated with clinical and radiological data to arrive at a final diagnosis. Results: Fine needle aspiration cytology was performed in various anatomic sites: liver (28 cases), pancreas (8 cases), lymph nodes (7 cases), ovary and gall bladder (3 cases each) and 2 cases each of gastrointestinal tract and omentum. Thoracic aspirations were done from the lung (44 cases) and mediastinum (3 cases). The most common malignancy encountered in the abdomen was hepatocellular carcinoma (12 cases). Non-small cell carcinoma was the most common diagnoses amongst the lung lesions (15 cases). Conclusion: Ultrasonography and computed tomography guided fine needle aspiration cytology had a high sensitivity and specificity in diagnosing deep seated lesions. Keywords: Computed tomography; Deep-seated masses; Fine needle aspiration; Ultrasound DOI: 10.3126/jpn.v1i1.4444 Journal of Pathology of Nepal (2011) Vol.1, 17-21


1970 ◽  
Vol 20 (1) ◽  
pp. 25-31 ◽  
Author(s):  
RN Sarjer ◽  
AF Rabbi ◽  
A Hossain ◽  
MA Quddus ◽  
N Chowdhury ◽  
...  

Objective: To evaluate the diagnostic efficacy of computed tomography (CT) guided transthoracic fine needle aspiration cytology (FNAC) in the diagnosis of intrathoracic masses not approachable by ultrasound. Materials and Methods: CT guided FNAC of intrathoracic masses was done in 100 patients and they were followed up to the final diagnosis. The diagnostic accuracy, sensitivity, specificity, positive and negative predictive values of the procedures were calculated. Results: The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of CT guided transthoracic FNAC were 93.85%, 100%, 96%, 100% & 89.74% respectively for the diagnosis of sonographically nonapproachable malignant intrathoracic masses and 94.29%, 98.46%, 97%%, 97.06% & 96.97% respectively for benign intrathoracic masses. Conclusion: CT guided transthoracic FNAC is a highly sensitive and specific procedure in the diagnosis of intrathoracic masses that are not approachable by ultrasound. Keywords: Computed tomography; Fine needle aspiration cytology; Intrathoracic masses. DOI: http://dx.doi.org/10.3329/jdmc.v20i1.8568 J Dhaka Med Coll. 2011; 20(1) :25-31


Author(s):  
Vidhu Mahajan ◽  
Mansi Sharma ◽  
Jyotsna Suri ◽  
Surinder K. Atri ◽  
Nipun Kalsotra

Background: The present study was undertaken to evaluate the diagnostic usefulness of image guided fine needle aspiration cytology (FNAC) in various lung lesions-both neoplastic and non- neoplastic.Method: This retrospective study (Jan 2016-Dec 2018) included 34 cases of lung lesions with strong probable radiological diagnosis of lung neoplasm. Computed tomography (CT)-guided FNAC was performed and cytological smears were stained with May-Grunwald-Gimesa (MGG) stain and conventional Papanicolaou (Pap) stain.Result: A total of 34 cases of lung masses in our study, included 21 males (61.7%) and 13 females (38.2%). The age interval varied from 15 to 85 years; majority presenting in 6th and 7th decade of age. Smears were broadly categorized into unsatisfactory (n=2;5.88%), benign (n=3;8.82%), suspicious of malignancy (n=2;5.88%) and malignant lesions (n=27;79.41%). Benign category included 2 cases of tuberculosis and 1 case of abscess. Malignant category included the cases, diagnosed as squamous cell carcinoma(n=8); poorly differentiated carcinoma (n=6); small cell carcinoma (n=3); adenoma carcinoma (n=2); primitive neuroectodermal tumor (n=2); non-Hodgkins lymphoma (n=2) and plasmacytoma (n=1). Malignant category also included one case each of Metastatic Adenocarcinoma, adenoid cystic carcinoma, renal cell carcinoma with known primary site of Tumours.Conclusions: CT-guided FNAC is a less expensive, simple, fast, relatively safe and accurate procedure in the diagnosis of difficult lung lesions; the major limitation being the adequacy of the aspirate. 


2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Rajneesh Madhok ◽  
Ashish Gupta ◽  
Lalit Singh ◽  
Tanu Agarwal

INTRODUCTION: The study is an attempt to evaluate the sensitivity, specificity, positive predictive value, negative predictive value, p Value and complications of CT guided thoracic interventions fine needle aspiration cytology and core biopsy which are used for diagnosing benign and malignant thoracic lesions. MATERIAL AND METHODS: Study included 102 Patients (87 males and 15 females) with age group ranged from 15 to 87 years.A total of 143 CT guided interventions (84 FNAC’s and 59 core biopsies) were performed in 102 patients. The tissue obtained was sent to the laboratory for histopathological and cytological analysis for a final diagnosis which would contribute to patient management. RESULTS: All( 59) core biopsies were successful in procuring adequate tissue for histopathological analysis and the yield of core biopsies was 100% .However out of 84 FNAC’s only 4 were unsuccessful in procuring adequate tissue with a failure rate of 4.8%. Post procedural biopsy complications were only three (2.1%) which were small pneumothorax. There were 75 malignant lesions and 23 benign lesions based on cytology and histopathology (4 were excluded due to inadequate sample). There was good agreement between benign and malignant lesions diagnosed on CT and that diagnosed by pathology. The most common benign and malignant lesions were granulomatous lesion and squamous cell carcinoma. CONCLUSION: Percutaneous CT guided interventions like core biopsy and fine needle aspirations cytology are simple minimal invasive procedures with good patient acceptance and low morbidity and almost negligible mortality. CT guided interventions should be performed early for diagnosis of thoracic lesions.


2012 ◽  
Vol 29 (1) ◽  
pp. 30 ◽  
Author(s):  
Maggad Rangaswamy ◽  
Jayashree Krishnamurthy ◽  
Sunila ◽  
TogyThomas Zacharia ◽  
Gururajprasad Chennakeshaviah ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document