1395 Nivolumab-Induced Hemorrhagic Pancreatitis

2019 ◽  
Vol 114 (1) ◽  
pp. S771-S771 ◽  
Author(s):  
Wesley Rogers ◽  
Amit Mehta ◽  
Saurabh Mukewar ◽  
Rachel Niec ◽  
Danny Issa ◽  
...  
Keyword(s):  
Hemorrhagic Pancreatitis

THE SELECTIVE PROTEOLYTIC ENZYME INHIBITORY ACTION OF BENZETHONIUM CHLORIDE

1960 ◽  
Vol 38 (1) ◽  
pp. 25-32 ◽  
Author(s):  
Ivan T. Beck ◽  
E. Pinter ◽  
R. D. McKenna ◽  
H. Griff
Keyword(s):  
Subcutaneous Injection ◽  
Proteolytic Enzyme ◽  
Inhibitory Action ◽  
Hemorrhagic Pancreatitis ◽  
Benzethonium Chloride ◽  
Tryptic Activity ◽  
High Concentrations ◽  
Acute Hemorrhagic Pancreatitis ◽  
Very High

Acute hemorrhagic pancreatitis in humans is thought to be perpetuated by the autolytic processes catalyzed by trypsin and lipase. This study is an integral part of our search for trypsin and lipase inhibitors to be used in the treatment of this disease.Benzethonium chloride was found to inhibit tryptic activity in vitro. The proteolytic activity of rabbit's serum was inhibited, and the inhibition was most pronounced 6 to 12 hours after the subcutaneous injection of the compound. Fibrinolysin was also inhibited in vitro but benzethonium chloride had no inhibitory action on chymotrypsin, pepsin, or lipase.Serum proteins in vitro were precipitated only with very high concentrations of the compound. No significant protein changes were observed in sera of rabbits after the subcutaneous injection of the compound.

scholarly journals Acute Hemorrhagic Pancreatitis and Pseudocyst Due to Mumps

1974 ◽  
Vol 180 (1) ◽  
pp. 85-88 ◽  
Author(s):  
JEFFREY D. FELDSTEIN ◽  
FRANK R. JOHNSON ◽  
CHARLES A. KALLICK ◽  
S ALEXANDER DOOLAS
Keyword(s):  
Hemorrhagic Pancreatitis ◽  
Acute Hemorrhagic Pancreatitis

Aprotinin and Na2CaEDTA in Experimental Hemorrhagic Pancreatitis in Pigs

1987 ◽  
Vol 22 (1) ◽  
pp. 35-41 ◽  
Author(s):  
P. Puolakkainen ◽  
A. Paananen ◽  
M. Kaarne ◽  
T. Kuusi ◽  
M. Lempinen ◽  
...  
Keyword(s):  
Hemorrhagic Pancreatitis

Fatal Hemorrhagic Pancreatitis Following Chlorothiazide Administration in Pregnancy

1964 ◽  
Vol 24 (3) ◽  
pp. 337-342 ◽  
Author(s):  
STANLEY MINKOWITZ ◽  
HENRY B. SOLOWAY ◽  
J. EDWARD HALL ◽  
VALENTIN YERMAKOV
Keyword(s):  
Hemorrhagic Pancreatitis ◽  
In Pregnancy

Injection of Microspheres into Pancreatic Arteries Causes Acute Hemorrhagic Pancreatitis in the Rat

Pancreas ◽  
1990 ◽  
Vol 5 (2) ◽  
pp. 188-193 ◽  
Author(s):  
Falah Redha ◽  
Georg Uhlschmid ◽  
Rudolf W. Ammann ◽  
Andreas U. Freiburghaus
Keyword(s):  
Hemorrhagic Pancreatitis ◽  
Acute Hemorrhagic Pancreatitis ◽  
Pancreatic Arteries

scholarly journals The role of ductal obstruction on the course of hemorrhagic pancreatitis in the pig

1986 ◽  
Vol 1 (1) ◽  
pp. 51-59 ◽  
Author(s):  
L. Romero Farias ◽  
Charles F. Frey ◽  
Samuel French ◽  
Robert Gunther
Keyword(s):  
Hemorrhagic Pancreatitis
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