scholarly journals Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS): diagnostic criteria, features of epileptic seizures, and treatment approaches by the example of a clinical case

2017 ◽  
Vol 9 (4) ◽  
pp. 65-69
Author(s):  
M. A. Yamin ◽  
I. V. Chernikova ◽  
L. V. Araslanova ◽  
P. A. Shevkun
2019 ◽  
Vol 9 (5) ◽  
Author(s):  
Yamin MA ◽  
Belyaev OV ◽  
Araslanova LV

The paper describes a patient with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS). The features of the course and therapy of epilepsy in MELAS are discussed. The disease is known for its late diagnosis when years elapse from the onset of the clinical manifestations to diagnosis. The paper presents clinical criteria for the diagnosis of MELAS and the specific features of brain neuroimaging changes that allow identification of the disease at an early stage.


2019 ◽  
Vol 24 (3) ◽  
pp. 90-92 ◽  
Author(s):  
Kelsey Smith ◽  
Shannon Chiu ◽  
Christopher Hunt ◽  
Adithya Chandregowda ◽  
Dusica Babovic-Vuksanovic ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-2
Author(s):  
Jully M. Sanchez ◽  
Judy Ann Tan ◽  
Dimitrios Farmakiotis ◽  
Vikas Aggarwal

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a rare but important cause of stroke-like symptoms which can often be missed Thambisetty and Newman 2004. We describe a case of a young male presenting with stroke-like episodes, later diagnosed with MELAS in an attempt to improve the understanding about diagnosing MELAS in the appropriate clinical context.


2019 ◽  
Vol 08 (04) ◽  
pp. 114-120
Author(s):  
Mohammed Ilyas ◽  
Kailash Tulshiram Pawar ◽  
Mirza Waseem Mohammad Baig

AbstractReflex epilepsies are characterized by the presence of epileptic seizures, which are consistently or stereotypically evoked by a specific afferent stimulus (i.e., flashes of light, startles, a particular movement, or cognitive task). Seizures in them are generally refractory to medical treatment requiring polytherapy. Avoiding the trigger and antiepileptic therapy may likely abolish these seizures. However, in some cases, the use of specific technologies and addressing associated comorbidities may be necessary. In this study, we review the pathophysiological basis for different treatment approaches as well as recent advances in the management of reflex epilepsies.


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