scholarly journals Management of a Mycotic Thoracoabdominal Aortic Aneurysm Involving the Celiac Artery

2016 ◽  
Vol 43 (6) ◽  
pp. 528-530 ◽  
Author(s):  
Ahmet Dolapoglu ◽  
Kim I. de la Cruz ◽  
Joseph S. Coselli
Keyword(s):  
Aortic Aneurysm ◽  
Rare Case ◽  
Mycotic Aneurysm ◽  
Thoracoabdominal Aortic Aneurysm ◽  
Celiac Artery ◽  
Threatening Condition ◽  
Visceral Arteries ◽  
Life Threatening ◽  
In Situ Repair

A mycotic aneurysm that also involves the visceral arteries is a life-threatening condition. Surgical management typically consists of débridement and in situ repair with a Dacron graft and reimplantation of the involved visceral branches. We report a rare case of a mycotic saccular thoracoabdominal aortic aneurysm involving the celiac artery, with Streptococcus pneumoniae as the responsible organism. Successful repair of the aneurysm and concomitant revascularization of the celiac artery were achieved.

scholarly journals Rolipram Prevents the Formation of Abdominal Aortic Aneurysm (AAA) in Mice: PDE4B as a Target in AAA

Antioxidants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 460
Author(s):  
Saray Varona ◽  
Lídia Puertas ◽  
María Galán ◽  
Mar Orriols ◽  
Laia Cañes ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Inflammatory Cells ◽  
Progressive Increase ◽  
Phosphodiesterase 4 ◽  
Inflammatory Conditions ◽  
Abdominal Aortic ◽  
Threatening Condition ◽  
Life Threatening ◽  
Effective Therapeutic Strategy

Abdominal aortic aneurysm (AAA) is a common life-threatening condition characterized by exacerbated inflammation and the generation of reactive oxygen species. Pharmacological treatments to slow AAA progression or to prevent its rupture remain a challenge. Targeting phosphodiesterase 4 (PDE4) has been verified as an effective therapeutic strategy for an array of inflammatory conditions; however, no studies have assessed yet PDE4 in AAA. Here, we used angiotensin II (AngII)-infused apolipoprotein E deficient mice to study the involvement of the PDE4 subfamily in aneurysmal disease. PDE4B but not PDE4D was upregulated in inflammatory cells from both experimental and human AAA. The administration of the PDE4 selective inhibitor rolipram (3 mg/kg/day) to AngII-challenged mice (1000 ng/kg bodyweight/min) protected against AAA formation, limiting the progressive increase in the aortic diameter without affecting the blood pressure. The drug strongly attenuated the rise in vascular oxidative stress (superoxide anion) induced by AngII, and decreased the expression of inflammatory markers, as well as the recruitment of macrophages (MAC3+), lymphocytes (CD3+), and neutrophils (ELANE+) into the vessel wall. Rolipram also normalized the vascular MMP2 expression and MMP activity, preserving the elastin integrity and improving the vascular remodelling. These results point to PDE4B as a new therapeutic target for AAA.

scholarly journals Croup and COVID-19 in a child: a case report and literature review

2021 ◽  
Vol 14 (9) ◽  
pp. e244769
Author(s):  
Chee Chean Lim ◽  
Jeyasakthy Saniasiaya ◽  
Jeyanthi Kulasegarah
Keyword(s):  
Paediatric Intensive Care Unit ◽  
Rare Case ◽  
Prolonged Treatment ◽  
Third Wave ◽  
Close Monitoring ◽  
Limited Experience ◽  
Threatening Condition ◽  
Life Threatening ◽  
Severe Pathology ◽  
Inflammatory Syndrome

Croup (laryngotracheitis) is frequently encountered in the emergency department in a young child presenting with stridor. We describe a rare case of croup secondary to SARS-CoV-2 in an 18-month-old child who presented with stridor and respiratory distress and required urgent intubation. Subsequently, the child developed multisystem inflammatory syndrome in children (MIS-C). The child was monitored in paediatric intensive care unit. We would like to highlight that COVID-19 croup in children may be an indicator for MIS-C, and close monitoring is warranted as MIS-C is a life-threatening condition. Our limited experience suggests that COVID-19 croup especially if associated with MIS-C has an underlying more severe pathology and may require prolonged treatment in comparison with the typical croup or even COVID-19 croup. It is important to recognise this clinical entity during a time when most countries are in a third wave of COVID-19 pandemic.

scholarly journals Successful In Situ Repair for Mycotic Aneurysm of the Iliac Artery with Autologous Superficial Femoral Vein.

2003 ◽  
Vol 32 (2) ◽  
pp. 112-115
Author(s):  
Masato Yoshida ◽  
Tsutomu Shida ◽  
Nobuhiko Mukohara ◽  
Hidefumi Obo ◽  
Nobuhiro Tanimura ◽  
...  
Keyword(s):  
Iliac Artery ◽  
Mycotic Aneurysm ◽  
Femoral Vein ◽  
Superficial Femoral Vein ◽  
In Situ Repair

scholarly journals Successful Treatment of Clostridium difficile Bacteremia with Aortic Mycotic Aneurysm in a Patient with Prior Endovascular Aortic Aneurysm Repair

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Kairav Shah ◽  
Rebecca Brauch ◽  
Kartikeya Cherabuddi
Keyword(s):  
Clostridium Difficile ◽  
Aortic Aneurysm ◽  
Mycotic Aneurysm ◽  
Bypass Graft ◽  
Endovascular Aortic Aneurysm Repair ◽  
Life Threatening ◽  
History Of ◽  
Gastrointestinal Colonization ◽  
Aneurysm Repair ◽  
Aortic Aneurysm Repair

The clinical spectrum of Clostridium difficile infection can range from benign gastrointestinal colonization to mild diarrhea and life threatening conditions such as pseudomembranous colitis and toxic megacolon. Extraintestinal manifestations of C. difficile are rare. Here, we report a patient with a history of an endovascular aortic aneurysm repair (EVAR) presenting with an endovascular leak complicated by C. difficile bacteremia and a mycotic aneurysm. He was successfully treated with an explant of the EVAR, an aorto-left renal bypass, and aorto-bi-iliac bypass graft placement along with a six-week duration of intravenous vancomycin and oral metronidazole.

Endovascular Repair of a Type III Thoracoabdominal Aortic Aneurysm in a Patient with Occlusion of Visceral Arteries

2007 ◽  
Vol 30 (4) ◽  
pp. 793-796 ◽  
Author(s):  
Chris Klonaris ◽  
Athanasios Katsargyris ◽  
Athanasios Giannopoulos ◽  
Sotiris Georgopoulos ◽  
Chris Tsigris ◽  
...  
Keyword(s):  
Aortic Aneurysm ◽  
Endovascular Repair ◽  
Thoracoabdominal Aortic Aneurysm ◽  
Type Iii ◽  
Visceral Arteries

scholarly journals Antegrade in situ fenestrated endovascular repair of a ruptured thoracoabdominal aortic aneurysm

2020 ◽  
Vol 6 (3) ◽  
pp. 416-421
Author(s):  
Louis L. Zhang ◽  
Fred A. Weaver ◽  
Vincent L. Rowe ◽  
Kenneth R. Ziegler ◽  
Gregory A. Magee ◽  
...  
Keyword(s):  
Aortic Aneurysm ◽  
Endovascular Repair ◽  
Thoracoabdominal Aortic Aneurysm

scholarly journals Antegrade In Situ Multibranched Endografting for Emergent Thoracoabdominal Aortic Aneurysm Repair

2020 ◽  
Vol 72 (1) ◽  
pp. e270
Author(s):  
Miguel F. Manzur ◽  
Louis Zhang ◽  
Gregory A. Magee ◽  
Kenneth R. Ziegler ◽  
Fred A. Weaver ◽  
...  
Keyword(s):  
Aortic Aneurysm ◽  
Thoracoabdominal Aortic Aneurysm ◽  
Thoracoabdominal Aortic Aneurysm Repair ◽  
Aneurysm Repair ◽  
Aortic Aneurysm Repair

scholarly journals Thoracic aortic aneurysm causing aorto-esophageal fistula—our experience with a rare disease

2020 ◽  
Vol 2020 (7) ◽  
Author(s):  
Aakriti Yadav ◽  
Uttam Krishna Shrestha ◽  
Kajan Raj Shrestha ◽  
Dinesh Gurung
Keyword(s):  
Aortic Aneurysm ◽  
Thoracic Aortic Aneurysm ◽  
Sudden Onset ◽  
Massive Hemoptysis ◽  
Esophageal Fistula ◽  
Feeding Jejunostomy ◽  
Intravenous Antibiotics ◽  
Threatening Condition ◽  
Life Threatening ◽  
Upper Gastrointestinal

Abstract Aorto-esophageal fistula is a life-threatening condition, accounting for a small number of cases of upper gastrointestinal bleeding where patients present with one or more features of Chiari’s triad. We present the case of a 43-year-old woman, referred to us with symptoms of central chest pain, sudden onset dysphagia followed by massive hemoptysis. She was diagnosed with an aorto-esophageal fistula due to a ruptured thoracic aortic aneurysm and rushed for an emergency endovascular thoracic aortic stent and feeding jejunostomy with intravenous antibiotics and supportive care. After 6 weeks of surgery, the patient was re-evaluated to plan for an esophageal stent if required. The purpose of this presentation is to make the surgical fraternity aware of the gravity of this disease and novel techniques to manage it.

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