scholarly journals Monocyte chemoattractant protein-1 and matrix metalloproteinase-9 in patients with type 2 cardiorenal syndrome with chronic heart failure and diabetes type 2 depending on the rate of glomerular filtration

2014 ◽  
Vol 0 (5) ◽  
Author(s):  
P. G. Kravchun ◽  
A. V. Narizhnaya ◽  
N. G. Rindina
2014 ◽  
Vol 18 (4 (72)) ◽  
Author(s):  
A. V. Narizhna ◽  
P. G. Kravchun ◽  
N. G. Ryndina

The aim is to assess the existence and nature of the relationship between cytokine status on the basis of the determination of pro-inflammatory IL-1β, anti-IL-10, the functional state of the kidneys and the indicator fibrolysis MMP-9 in patients with CRS against the background of chronic heart failure and 2 diabetes type. The imbalance in the system of cytokines was associated with hyperactivity of antifibrotic factor MMP-9 in patients with CRS with a chronic heart failure and type 2 diabetes as a background. High levels of MMP-9 are involved in disorders of the functional state of kidneys, more pronounced changes in the tubulointerstitial component less - tubular. Study is to determine the prospects predictor’s values of MMP-9 in progress of CRS with the background of CHF and type 2 diabetes.


2016 ◽  
Vol 12 (3) ◽  
pp. 186-194 ◽  
Author(s):  
Jois Preeti ◽  
Mebazaa Alexandre ◽  
Pupalan Iyngkaran ◽  
Thomas C. Merlin ◽  
Ronco Claudio

Sign in / Sign up

Export Citation Format

Share Document