scholarly journals The Impact of Antithrombotic Regimens on Clinical Outcomes After Endovascular Intervention and Bypass Surgery for Infrapopliteal Artery Disease

2019 ◽  
Vol 10 (5) ◽  
pp. 255-267
Author(s):  
Amol Gupta ◽  
Michael S. Lee ◽  
Kush Gupta ◽  
Vinod Kumar ◽  
Sarath Reddy
Keyword(s):  
Clinical Outcomes ◽  
Bypass Surgery ◽  
Endovascular Intervention ◽  
Infrapopliteal Artery ◽  
Artery Disease ◽  
The Impact

Impact of iliac arterial calcification on procedure success and long-term outcomes among patients undergoing endovascular intervention

Vascular ◽  
2021 ◽  
pp. 170853812110209
Author(s):  
Omer Tasbulak ◽  
Mustafa Duran ◽  
Tugba Aktemur ◽  
Arda Guler ◽  
Serkan Kahraman ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Strong Association ◽  
Endovascular Intervention ◽  
Arterial Calcification ◽  
Success Rates ◽  
Long Term Outcomes ◽  
Iliac Arteries ◽  
Artery Disease ◽  
The Impact

Objectives Vascular calcification is a well-known phenomenon and affects coronary and carotid arteries as well as other arterial beds. Presence of arterial calcification is associated with major adverse events in patients undergoing percutaneous coronary artery or carotid artery intervention. Even though there is a clear association between worse outcome and coronary-carotid calcification, there is no research that interrogated the relationship between iliac arterial calcification and clinical outcomes because of lack of data. Therefore, in this study, we aimed to investigate the impact of iliac arterial calcification on procedure success rates and long-term outcomes among patients undergoing endovascular intervention. Methods The records of 453 consecutive patients who underwent endovascular intervention due to symptomatic peripheral artery disease were analyzed. Patients were divided into two groups based on the presence or absence of heavy calcification of iliac arteries. For each group, technical aspects of procedures and subsequent clinical outcomes were analyzed. Results According to our study, the rate of restenosis following endovascular intervention at 6 and 12 months were similar between two groups. On the other hand, long-term restenosis was significantly higher in patients with heavy calcification of iliac arteries as compared to patients with low calcification on iliac arteries (32.2% vs. 12.8%, p <  0.05). Conclusions Our data showed that there was a strong association between heavy calcification of iliac arteries and long-term restenosis in patients undergoing endovascular intervention.

The impact of asymptomatic carotid artery disease on the intraoperative course of coronary artery bypass surgery

Perfusion ◽  
2003 ◽  
Vol 18 (1) ◽  
pp. 15-18 ◽  
Author(s):  
Martin Dworschak ◽  
Martin Czerny ◽  
Michael Grimm ◽  
Georg Grubhofer ◽  
Walter Plöchl
Keyword(s):  
Coronary Artery ◽  
Carotid Artery ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Neurological Injury ◽  
Asymptomatic Carotid ◽  
Artery Disease ◽  
The Impact

Asymptomatic carotid artery stenosis (CAS) may result in neurological injury after coronary artery bypass surgery, but routine preoperative carotid screening is not undisputed. We studied whether routinely determined carotid duplex results, beyond detecting high-risk patients, additionally influence intraoperative course. One hundred and eight patients without new signs of impaired cerebral circulation were investigated. Anesthesiology, perfusionist records, and patient files were reviewed for patient characteristics, intraoperative variables and postoperative neurological sequelae. There was a higher incidence of prior cerebrovascular events and peripheral artery disease in CAS patients (p B /0.05). Pulsatile flow was employed more frequently in this group (p B /0.05). Severe hyperventilation, hyperglycemia, hemodilution, hyperthermia, and lactacidosis were avoided in both groups. However, labile hemodynamics of CAS patients required more corrective interventions (p B /0.05). There was also a tendency toward greater mortality. Stroke and transient ischemic attack (TIA) occurred in two patients without CAS. Since CAS was associated with a greater degree of cardiovascular instability requiring frequent measures to control hemodynamics, positive duplex results should heighten vigilance. Although CAS does not appear to be the major source of cerebral ischemia, it involves significant comorbidity.

scholarly journals Major Infections after Blood Transfusion in Isolated Coronary Artery Bypass Surgery Patients: A Meta-Analysis

Blood ◽  
2020 ◽  
Vol 136 (Supplement 1) ◽  
pp. 25-25
Author(s):  
Osama Mosalem ◽  
Shouq Kherallah ◽  
Mark Mujer ◽  
Priyal Agarwal ◽  
Merryl Treasa Varghese ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Blood Transfusion ◽  
Clinical Outcomes ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Wound Infections ◽  
Sternal Wound Infections ◽  
The Impact

BACKGROUND Blood transfusion in patients undergoing coronary artery bypass surgery (CABG) remains high despite advances in perioperative blood conservation. Several studies have shown poorer clinical outcomes in isolated CABG patients who receive blood products, including an increased rate of renal failure, non-fatal myocardial infarction, and death. Our study sought to determine the impact of blood transfusion on sternal wound infections and other major infections in patients who undergo isolated CABG. METHODS We performed a systematic search using PubMed, Google Scholar, EMBASE, SCOPUS, and ClinicalTrials.gov without language restriction until May 15, 2020. A random-effects model was utilized to calculate risk ratio (RR) and mean difference (MD) with 95% confidence interval (CI). RESULTS In patients undergoing isolated CABG, sternal wound infections [RR 1.73 (95% CI: 1.35 to 2.20; p&lt;0.0001)] and overall major infections [RR 1.70 (95% CI: 1.39 to 2.08; p&lt;0.0001)] were significantly higher in those who received a periprocedural blood transfusion. Thirty-day mortality was lower in patients who did not receive any transfusion [RR 2.46 (95% CI: 1.09-5.56;p=0.03)]. The test of heterogeneity was low for clinical outcomes aside from 30-day mortality. CONCLUSION Periprocedural blood transfusion is associated with an increased risk of sternal wound infections and major infections and higher 30-day mortality in patients who undergo isolated CABG Disclosures No relevant conflicts of interest to declare.

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