The Effects of Borderline Personality and Sociodemographic traits on Self-Harm and Suicidal Behaviors in Substance Use Disorder

Background: The published evidence supports dialectical behavioral therapy (DBT) efficacy to treat patients with borderline personality disorder and particular emphasis on emotion dysregulation as a psychopathological construct. Aim: To assess the efficacy of DBT for improving emotion dysregulation among patients with a dual diagnosis of borderline personality disorder and substance use disorder. Methods: We recruited 40 patients meeting DSM-5 criteria for borderline personality disorder and substance use disorder and assigned them to two groups of 20 participants each. One group underwent DBT therapy, and the other group followed a treatment-as-usual (TAU) protocol over one year. We used the difficulties in emotion regulation scale (DERS) scores at baseline, immediately after therapy, and four months after treatment to assess emotion dysregulation. Results: We found significant improvements (p<0.05) in the DBT group after therapy that was maintained at least for four months afterward based on the DERS scores (including subscale scores). More patients dropped out of the treatment in the TAU group than in the DBT group. Conclusion: DBT is a potentially effective psychological intervention to treat emotion dysregulation in patients with borderline personality disorder and substance use disorder.

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Borderline Personality Disorder Symptom Clusters Predict Substance Use Disorder Symptoms in a Nonclinical Sample

Journal of Social and Clinical Psychology ◽

10.1521/jscp.2011.30.7.722 ◽

2011 ◽

Vol 30 (7) ◽

pp. 722-731

Author(s):

Amy J. Mikolajewski ◽

Scott Pizzarello ◽

Jeanette Taylor

Keyword(s):

Substance Use ◽

Borderline Personality Disorder ◽

Personality Disorder ◽

Substance Use Disorder ◽

Borderline Personality ◽

Symptom Clusters ◽

Disorder Symptom ◽

Nonclinical Sample

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The two-faceted nature of impulsivity in patients with borderline personality disorder and substance use disorder

Drug and Alcohol Dependence ◽

10.1016/j.drugalcdep.2016.03.015 ◽

2016 ◽

Vol 163 ◽

pp. 48-54 ◽

Cited By ~ 12

Author(s):

Aniko Maraz ◽

Bálint Andó ◽

Péter Rigó ◽

János Harmatta ◽

Gáspár Takách ◽

...

Keyword(s):

Substance Use ◽

Borderline Personality Disorder ◽

Personality Disorder ◽

Substance Use Disorder ◽

Borderline Personality

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A systematic review of interventions for co-occurring substance use disorder and borderline personality disorder

Journal of Substance Abuse Treatment ◽

10.1016/j.jsat.2011.05.004 ◽

2011 ◽

Vol 41 (4) ◽

pp. 363-373 ◽

Cited By ~ 31

Author(s):

Amy Pennay ◽

Jacqui Cameron ◽

Tiffany Reichert ◽

Heidi Strickland ◽

Nicole K. Lee ◽

...

Keyword(s):

Systematic Review ◽

Substance Use ◽

Borderline Personality Disorder ◽

Personality Disorder ◽

Substance Use Disorder ◽

Borderline Personality

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DBT for Co-morbid Borderline Personality Disorder and Substance use Disorder Without Drug Replacement in Egyptian Outpatient Settings: A Non-randomized Trial

European Psychiatry ◽

10.1016/j.eurpsy.2017.02.068 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S260-S261 ◽

Cited By ~ 1

Author(s):

A. Abdelkarim ◽

T. Molokhia ◽

A. Rady ◽

A. Ivanoff

Keyword(s):

Substance Use ◽

Hospital Admission ◽

Substance Use Disorder ◽

Dialectical Behavior Therapy ◽

Emotional Regulation ◽

Drugs Of Abuse ◽

Borderline Personality ◽

Psychotherapeutic Treatment ◽

Treatment As Usual ◽

One Year

BackgroundDialectical behavior therapy has demonstrated effectiveness for patients suffering from co-morbid borderline personality and substance use disorder. The current study tries to replicate results of previous studies in a mixed gender sample of Egyptian outpatients.AimThe aim of the current study was to examine the effectiveness of DBT without drug replacement relative to treatment as usual “TAU” in improving behavioral outcomes related to SUD and BPD, and improving emotional regulation.MethodsForty outpatients with co-morbid BPD and SUD in Alexandria and Cairo were assigned for one year either to comprehensive DBT program (20 patients), or TAU defined as ongoing outpatient psychotherapeutic treatment from referring center (20 patients). Patients were assessed at baseline and follow up assessment at 4, 8, 12 and 16 months was done using Arabic version of Difficulties in Emotion Regulation Scale (DERS), urine multidrug screen and time line follow-back method for assessment of alcohol and substance use history.ResultsFollowing one year of treatment, DBT group showed significantly lower doses of drugs used, DERS score, rates of hospital admission, ER visits, suicidal attempts and episodes of NSSI. Also, DBT patients showed markedly increased retention in treatment and longer duration of total alcohol abstinence and other drugs of abuse. Positive outcomes were maintained for four months post-treatment.ConclusionDBT demonstrated superior efficacy in comparison to TAU for treatment of Egyptian patients suffering from co-morbid borderline personality and substance use disorder across behavioral domains of SUD, BPD and reduction hospital admission, emergency room visits and DERS score.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Residential eating disorder outcomes associated with screening positive for substance use disorder and borderline personality disorder

International Journal of Eating Disorders ◽

10.1002/eat.23028 ◽

2019 ◽

Vol 52 (3) ◽

pp. 309-313 ◽

Cited By ~ 5

Author(s):

Thomas J. Weigel ◽

Shirley B. Wang ◽

Jennifer J. Thomas ◽

Kamryn T. Eddy ◽

Casey Pierce ◽

...

Keyword(s):

Substance Use ◽

Eating Disorder ◽

Borderline Personality Disorder ◽

Personality Disorder ◽

Substance Use Disorder ◽

Borderline Personality

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Intensive Dialectical Behavior Treatment for Individuals With Borderline Personality Disorder With and Without Substance Use Disorders

Frontiers in Psychology ◽

10.3389/fpsyg.2021.629842 ◽

2021 ◽

Vol 12 ◽

Author(s):

Frank D. Buono ◽

Kaitlyn Larkin ◽

David Rowe ◽

M. Mercedes Perez-Rodriguez ◽

Matthew E. Sprong ◽

...

Keyword(s):

Substance Use ◽

Borderline Personality Disorder ◽

Personality Disorder ◽

Substance Use Disorders ◽

Substance Use Disorder ◽

Treatment Program ◽

Coping Skills ◽

Behavioral Therapy ◽

Borderline Personality ◽

Depression Symptom

Treatment of borderline personality disorder (BPD) with comorbid substance use disorder can be challenging due to symptom overlap and limited assessment methods. Preliminary evidence has shown promising effectiveness of dialectical behavioral therapy (DBT) for BPD with comorbid substance use disorders. The current study compared the benefits of a 28-day transitional DBT treatment program for individuals with BPD with and without substance use disorders through evaluating the changes in coping skills, generalized anxiety, and depression symptom scales at admission and discharge. A total of 76 patients were split into two groups: Group 1 consisted of individuals with BPD without substance use disorders (n = 41), and Group 2 involved individuals with BPD and a substance use disorder (SUD) (n = 35). A univariate general linear model showed significant differences between the two groups in improvement of coping skills and depressive symptoms. After a 28-day transitional DBT treatment program there were significant decreases from severe to moderate depression scores in both groups. Our findings support the effectiveness of DBT treatment in patients with comorbid BPD and SUD.

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