The spatial and temporal variations of wind field and the atmospheric turbulence characteristics are important factors that affect the migration and dispersion of local atmospheric pollutants. Since the numerical meteorological forecasting system with high resolution is the foundation of atmospheric dispersion simulation, more and more attention has been drawn to the application of numerical weather prediction systems in wind field prediction and atmospheric simulation. This paper reviewed the widespread application of numerical weather prediction systems in wind field prediction and atmospheric simulation with the focus on the mesoscale weather forecasting system with high resolution, for instance WRF and MM5, as well as the requirement for numerical weather prediction in the simulation research of wind field prediction and atmospheric dispersion.