scholarly journals Favorable Evolution of a Patient with Thromboembolic Pulmonary Hypertension

2017 ◽  
Vol 23 (2) ◽  
pp. 94-98
Author(s):  
Cristina Nedelcu ◽  
Irinel Raluca Parepa ◽  
Laura Mazilu ◽  
Andra-Iulia Suceveanu ◽  
Luminita Matei ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Young Adulthood ◽  
Primary Pulmonary Hypertension ◽  
Endothelin Receptor ◽  
Vein Thrombosis ◽  
Thromboembolic Pulmonary Hypertension ◽  
History Of ◽  
Recurrent Deep Vein Thrombosis ◽  
Deep Vein ◽  
Phosphodiesterase 5

AbstractWe present a case of severe thromboembolic pulmonary hypertension in a patient with history of recurrent deep vein thrombosis and pulmonary restrictive disease due to pulmonary and vertebral tuberculosis in young adulthood. He was considered not eligible in the National Program for Primary Pulmonary Hypertension, being referred for thoracic surgery, but he was considered unfit for thrombendarterectomy. Despite guidelines, we administered him specific medical therapy (phosphodiesterase-5 inhibitors and endothelin receptor antagonists). His clinical evolution was satisfactory, with increasing effort tolerance and decreasing need for ambulatory oxigenotherapy.

An unusual case of warfarin-induced pinna skin necrosis

2008 ◽  
Vol 123 (6) ◽  
pp. 685-688 ◽  
Author(s):  
M Martinez Del Pero ◽  
S Verma ◽  
A Espeso ◽  
M Griffiths ◽  
P Jani
Keyword(s):  
Skin Necrosis ◽  
Protein S ◽  
Unusual Site ◽  
Vein Thrombosis ◽  
Low Protein ◽  
Menopausal Women ◽  
Diagnostic Confusion ◽  
History Of ◽  
Recurrent Deep Vein Thrombosis ◽  
Deep Vein

AbstractIntroduction:Warfarin-induced skin necrosis is a rare but recognised complication of this drug. The condition predominantly affects the breasts, buttocks and thighs of obese, peri-menopausal women. We present the case of a patient with the condition in an unusual site, and we discuss the management challenges involved.Case report:An 82-year-old man presented to the ENT department with a diagnosis of pinna haematoma. There was no history of trauma or infection. The patient was taking warfarin long-term for recurrent deep vein thrombosis. Two weeks prior to admission, the patient had had a loading course of warfarin following surgery. Multiple clinical teams were involved in treatment. The only abnormal laboratory investigation was a low protein S level; biopsy showed skin necrosis.Conclusion:In this case, the unusual presentation created diagnostic confusion, and may have precipitated aggressive surgical debridement. However, a more conservative management strategy was used, which we would recommend in future.

Plasma Lp(a) Levels Are Increased in Patients with Chronic Thromboembolic Pulmonary Hypertension

1998 ◽  
Vol 80 (08) ◽  
pp. 231-232 ◽  
Author(s):  
M. Ignatescu ◽  
G. Zorn ◽  
M. Kneussl ◽  
G. Maurer ◽  
I. M. Lang ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Pulmonary Arteries ◽  
Chronic Thromboembolic Pulmonary Hypertension ◽  
Vein Thrombosis ◽  
Large Size ◽  
Number Of Patients ◽  
Thromboembolic Pulmonary Hypertension ◽  
Pulmonary Arterial ◽  
Genetically Determined ◽  
Deep Vein

SummaryChronic thromboembolic pulmonary hypertension (CTEPH) is a disease resulting from the thromboembolic obstruction of the segmental and/or large size pulmonary arteries, subsequently leading to pulmonary arterial hypertension. Incomplete resolution of acute pulmonary emboli and thrombus organization are believed to be important for the development of the disease. Primary pulmonary hypertension (PPH) is a further disease that at present is poorly understood but shows a clinical picture similar to CTEPH. Since lipoprotein(a) [Lp(a)], a genetically determined risk factor for atherosclerosis and thrombosis, has been found increased in plasma of patients with deep vein thrombosis and pulmonary embolism, we measured plasma Lp(a) levels in 40 patients with CTEPH and 50 patients with PPH and compared them to 50 matched controls. The median for Lp(a) plasma levels was significantly higher in CTEPH patients (26.6 mg/dl) than in PPH patients (9.6 mg/dl) and controls (7.2 mg/dl). Increased plasma Lp(a) could, therefore, play a significant role in the mechanisms of ongoing thrombosis and thrombus organization in CTEPH, while its possible role in PPH can be limited to a small number of patients.

scholarly journals Chronic thromboembolic pulmonary hypertension in young woman with history of caesarian section

2015 ◽  
Vol 23 (4) ◽  
pp. 232-8 ◽  
Author(s):  
Nitia A. Asbarinsyah ◽  
Rarsari S. Soerarso ◽  
Nani Hersunarti ◽  
Bambang B. Siswanto
Keyword(s):  
Pulmonary Hypertension ◽  
Medical Condition ◽  
Chronic Thromboembolic Pulmonary Hypertension ◽  
Caesarian Section ◽  
Pulmonary Angiography ◽  
Diagnostic Tools ◽  
Vein Thrombosis ◽  
Pulmonary Vasodilator ◽  
Thromboembolic Pulmonary Hypertension ◽  
History Of

Chronic thromboembolic pulmonary hypertension (CTEPH) is one of subgroups of pulmonary hypertension. This is a serious medical condition that severely under diagnosed. CTEPH is commonly underdiagnosed due to non specific symptoms and lack of diagnostic tools. The aim of this presentation is to discuss the etiology, risk factors, diagnosis and management of CTEPH. A 36-year-old woman presented with easily fatigue and dyspneu on effort since two years ago. The symptom occured about three months after she gave birth with caesarian section due to preeclampsia. Further history taking, physical examination, electrocardiography (ECG) and echocardiography were highly suggestive of pulmonary hypertension. No deep vein thrombosis (DVT) was found on vascular femoral sonography. It was found after the lung perfusion scintigraphy performed that she actually had CTEPH. This patient was categorized as inoperable because CT pulmonary angiography showed no thrombus. The patient got pulmonary vasodilator and oral anticoagulant for lifelong.

Spontaneous retroperitoneal haemorrhage secondary to anticoagulation polypharmacy

2021 ◽  
Vol 14 (8) ◽  
pp. e242934
Author(s):  
Mohammed M Uddin ◽  
Tanveer Mir ◽  
Amir Khalil ◽  
Zeenat Bhat ◽  
Anita Maria Noronha
Keyword(s):  
Management Strategies ◽  
Vein Thrombosis ◽  
Anticoagulation Agents ◽  
Concurrent Use ◽  
Life Threatening ◽  
History Of ◽  
Recurrent Deep Vein Thrombosis ◽  
Retroperitoneal Haemorrhage ◽  
Deep Vein

Retroperitoneal haemorrhage (RH) is not uncommon in patients with provoking events like trauma. However, spontaneous RH (SRH) is a rare and life-threatening complication described as the development of bleeding into the retroperitoneal cavity, appearing spontaneously and without a preceding history of trauma or other predisposing illness. We are reporting a case of an elderly patient with recurrent deep vein thrombosis who had developed SRH secondary to concurrent use of multiple anticoagulation agents, resulting from poor healthcare follow-up and lack of sufficient medication reconciliation. This article highlights the significance of recognising risk factors for SRH, as well as management strategies through literature review.

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