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2021 ◽  
Vol 36 (2) ◽  
pp. 200-205
Author(s):  
Jung Hyun Park

Unlike other aneurysms, blood blister-like aneurysms(BBA) occur at non-branching sites, are commonly located at the dorsal wall of the supraclinoid internal carotid artery (ICA), and are suspected to arise from dissecting aneurysms. They are typically diagnosed after a bleed because of their small size and unusual site. Therefore, lesions exist after brain computed tomography or magnetic resonance imaging, but they are often not found. In the case of BBA, which have a high risk of recurrence, the treatment is difficult, and selecting the treatment method is also challenging. This paper describes the treatment of a BBA with internal trapping of the ICA that eventually recurred despite performing coil embolization twice.


Hemato ◽  
2021 ◽  
Vol 2 (4) ◽  
pp. 769-780
Author(s):  
Uzma Faruqi ◽  
Karen A. Breen

Philadelphia chromosome negative myeloproliferative neoplasms (MPN) are clonal haematopoietic stem cell disorders. Of the MPNs, polycythaemia vera (PV) and essential thrombocythaemia (ET) confer a high thrombotic risk which may be the presenting feature of the disease. Thrombotic complications consist of both arterial and venous events and the presence of the JAK2 V617F mutation is associated with higher risk. Patients presenting with an unprovoked thrombus, particularly at an unusual site, e.g., splanchnic circulation, should be screened for the presence of this mutation. Historically, warfarin has been the only option for oral anticoagulation; however, there is now increasing evidence and practise to use direct oral anticoagulants (DOACs) in cancer. The seminal randomised control trials have demonstrated non-inferiority compared to low molecular weight heparin (LMWH) with a preferable bleeding profile. DOACs are now the first line treatment for atrial fibrillation and venous thromboembolic disease, as recommended by NICE, and therefore there is increasing familiarity with these agents. Furthermore, there are now targeted antidotes available. This paper reviews evidence for efficacy and safety of DOACs in MPN. Whilst no randomised control trials have been performed, several retrospective studies and reviews of registry data have reproducibly demonstrated that, alongside cytoreduction, DOACs represent an effective modality of anticoagulation for treatment of venous thromboembolism in MPN. Furthermore, dosing regimens provide the option for longer term secondary prophylaxis. Use of DOACs in arterial thrombosis is an area for future development and there is already some evidence for utility in peripheral vascular disease.


Author(s):  
G. Rodríguez-Iranzo ◽  
S. Grixolli-Mazzon ◽  
H. González-Valdivia ◽  
E. Casas-Gimeno

Author(s):  
Motaip H. Alrawili ◽  
Rakan Aldusari ◽  
Samir Alsayegh ◽  
Faten Al Robian
Keyword(s):  

2021 ◽  
Vol 8 (4) ◽  
pp. 526-529
Author(s):  
Mamta Kripalani ◽  
Rakhi V Jagadale ◽  
Makarand V Khochikar

Extra-gonadal teratomas are rare and occur at various sites with the retroperitoneum being an unusual site. We report a case of an adenocarcinoma arising in a mature retroperitoneal teratoma with bilateral lung metastasis in a young female. Around less than 20 such cases have been reported in literature with the present case being probably second in the Indian scenario and the first to have adenocarcinomatous component matastasize to lungs. We hereby emphasize on the importance of looking for such suspicious areas in a teratoma in order to tailor subsequent management.


2021 ◽  
Vol 8 (4) ◽  
pp. 497-499
Author(s):  
Uttara K Aloorker ◽  
Narendra R Patil

Cystic lymphangioma is a benign lymphatic system malformation that occurs usually in children. Most common site being cervicofacial region followed by axilla; the cases in the chest wall are very rare. We report a case of male infant with cystic lymphangioma occurring at an unusual site- over the sternum.


2021 ◽  
Vol 6 (4) ◽  
pp. 311-315
Author(s):  
Rakhi V Jagdale ◽  
Mamta V Kripalani ◽  
Jaydeep N Pol ◽  
Sachin J Patil ◽  
Santosh S Kullolli

Cutaneous meningiomas (CM) are rare variants of meningiomas which are further classified into three subtypes. Type I CM (TICM) or Rudimentary meningocele (RM) is an uncommon developmental anomaly in which meningothelial elements are displaced into the skin and soft tissue. We present a case of 11 year boy with an upper back swelling since early childhood. His MRI spine showed a lesion at T4-T7 level with a fistulous tract connecting it to dural sac. Histopathology revealed clusters of oval to spindle cells arranged in whorls amidst collagen bundles and psammoma bodies. On immunohistochemistry these cells expressed EMA and Vimentin. A diagnosis of TICM was rendered based on these characteristic clinico-radiological & histopathological features. TICM pose a diagnostic challenge clinically and histopathologically and have an excellent prognosis. This is the 4 Indian case of RM and the 1 case of RM to be located in the spine in the Indian literature.


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