Outcome of monochorionic-biamniotic twins conceived by assisted reproduction: a population-based study

2016 ◽  
Vol 44 (8) ◽  
Author(s):  
Andreja Trojner Bregar ◽  
Isaac Blickstein ◽  
Ivan Verdenik ◽  
Miha Lucovnik ◽  
Natasa Tul
Keyword(s):  
Assisted Reproduction ◽  
Perinatal Outcomes ◽  
Population Based ◽  
Monochorionic Twins ◽  
Population Based Study ◽  
Maternal Characteristics ◽  
Assisted Reproduction Technology ◽  
Increased Risk ◽  
Adverse Perinatal Outcomes ◽  
Twin Pregnancies

AbstractObjecive:To evaluate the perinatal outcome of monochorionic-diamniotic twins conceived by assisted reproduction technology (ART).Methods:We compared data from a national population-based perinatal registry on perinatal outcomes of monochorionic-diamniotic twins conceived by ART with their dichorionic counterparts and with spontaneous monochorionic-diamniotic twins. We compared maternal characteristics, pregnancy complications and perinatal outcomes.Results:Monochorionic-diamniotic twin pregnancies (n=45) comprised 5.5% of all ART twins, and 9.3% of all monochorionic twins in this dataset. ART does not appear to increase the already high risk of monochorionicity compared to spontaneous conception, with the latter having an increased incidence for birth weight <1500 g [odds ratio (OD) 2.6, 95% confidence interval (CI) 1.2–5.4].Conclusion:Our results disagree with hospital-based data and suggest that monochorionic-diamniotic twins following ART are not at increased risk of adverse perinatal outcomes compared to spontaneous monochorionic-diamniotic twins as well as to dichorionc twins conceived by ART.

scholarly journals Perinatal outcomes of twin births conceived using assisted reproduction technology: a population-based study

2008 ◽  
Vol 23 (8) ◽  
pp. 1941-1948 ◽  
Author(s):  
S. L. Boulet ◽  
L. A. Schieve ◽  
A. Nannini ◽  
C. Ferre ◽  
O. Devine ◽  
...  
Keyword(s):  
Assisted Reproduction ◽  
Perinatal Outcomes ◽  
Population Based ◽  
Population Based Study ◽  
Assisted Reproduction Technology

scholarly journals Trends in Prevalence of Diabetes among Twin Pregnancies and Perinatal Outcomes in Catalonia between 2006 and 2015: The DIAGESTCAT Study

2021 ◽  
Vol 10 (9) ◽  
pp. 1937
Author(s):  
Lucia Gortazar ◽  
Juana Antonia Flores-Le Roux ◽  
David Benaiges ◽  
Eugènia Sarsanedas ◽  
Humberto Navarro ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Perinatal Outcomes ◽  
Population Based ◽  
Large For Gestational Age ◽  
Data Set ◽  
Population Based Study ◽  
Adverse Perinatal Outcomes ◽  
The Impact ◽  
Twin Pregnancies ◽  
Singleton Pregnancies

The aims of our study were to evaluate the trends in the prevalence of diabetes among twin pregnancies in Catalonia, Spain between 2006 and 2015, to assess the influence of diabetes on perinatal outcomes of twin gestations and to ascertain the interaction between twin pregnancies and glycaemic status. A population-based study was conducted using the Spanish Minimum Basic Data Set. Cases of gestational diabetes mellitus (GDM) and pre-existing diabetes were identified using ICD-9-CM codes. Data from 743,762 singleton and 15,956 twin deliveries between 2006 and 2015 in Catalonia was analysed. Among twin pregnancies, 1088 (6.82%) were diagnosed with GDM and 83 (0.52%) had pre-existing diabetes. The prevalence of GDM among twin pregnancies increased from 6.01% in 2006 to 8.48% in 2015 (p < 0.001) and the prevalence of pre-existing diabetes remained stable (from 0.46% to 0.27%, p = 0.416). The risk of pre-eclampsia was higher in pre-existing diabetes (15.66%, p = 0.015) and GDM (11.39%, p < 0.001) than in normoglycaemic twin pregnancies (7.55%). Pre-existing diabetes increased the risk of prematurity (69.62% vs. 51.84%, p = 0.002) and large-for-gestational-age (LGA) infants (20.9% vs. 11.6%, p = 0.001) in twin gestations. An attenuating effect on several adverse perinatal outcomes was found between twin pregnancies and the presence of GDM and pre-existing diabetes. As a result, unlike in singleton pregnancies, diabetes did not increase the risk of all perinatal outcomes in twins and the effect of pre-existing diabetes on pre-eclampsia and LGA appeared to be attenuated. In conclusion, prevalence of GDM among twin pregnancies increased over the study period. Diabetes was associated with a higher risk of pre-eclampsia, prematurity and LGA in twin gestations. However, the impact of both, pre-existing diabetes and GDM, on twin pregnancy outcomes was attenuated when compared with its impact on singleton gestations.

Birth weight discordance and adverse perinatal outcomes

2017 ◽  
Vol 45 (5) ◽  
Author(s):  
Shayesteh Jahanfar ◽  
Kenneth Lim ◽  
Eugenia Ovideo-Joekes
Keyword(s):  
Birth Weight ◽  
Perinatal Mortality ◽  
Apgar Score ◽  
Independent Risk Factor ◽  
Perinatal Outcomes ◽  
Population Based ◽  
Mortality And Morbidity ◽  
Increased Risk ◽  
Adverse Perinatal Outcomes ◽  
Discordant Twins

AbstractObjective:Our purpose was to examine the association between discordant growth and perinatal mortality and morbidity among twins with careful adjustment for maternal confounding factors.Study design:Two cohorts with and without chorionicity data were compared using generalized estimating modeling.Results:Our population-based dataset consisted of 12,656 individual twins from whom 4% (452/12,656) had≥30% growth discordance. A subgroup of this population with chorionicity information had an incidence of 7.3%≥30% growth discordance. In growth-discordant twins, perinatal mortality and morbidity were higher than concordant pairs (P<0.01). Low Apgar score and perinatal mortality were more frequent in growth-discordant twins compared with growth-concordant ones (all P<0.01).Conclusion:Birth weight discordance (BWD) places twins at increased risk of perinatal mortality. Growth discordance was also an independent risk factor for lower Apgar score of 5 min less than 5.

scholarly journals Pregnancy outcome in women with atrial septal defect: associated with in vitro fertilisation and pre-eclampsia

Open Heart ◽  
2019 ◽  
Vol 6 (2) ◽  
pp. e001148
Author(s):  
Sebastian Udholm ◽  
Louise Udholm ◽  
Camilla Nyboe ◽  
Ulrik Schiøler Kesmodel ◽  
Vibeke Elisabeth Hjortdal
Keyword(s):  
Atrial Septal Defect ◽  
Septal Defect ◽  
Reference Group ◽  
Reference Sample ◽  
Perinatal Outcomes ◽  
Population Based ◽  
In Vitro Fertilisation ◽  
Maternal Characteristics ◽  
Increased Risk

ObjectiveTo investigate in vitro fertilisation (IVF) in women with atrial septal defect (ASD), and to examine the maternal characteristics and outcome of pregnancy, as well as the fetal outcome of infants born by women with ASD.MethodsWe used population-based registries in this nationwide cohort study, including Danish individuals born before 1994 who received an ASD diagnosis between 1959 and 2014. Patients were compared with a random reference sample (ratio of 10 citizens per patient) matched by sex and age. The Danish Medical Birth Register (DMBR) contains data on all pregnancies and births in Denmark from 1977 to present. Risk of IVF treatment as well as maternal, pregnancy and fetal outcomes were compared.ResultsA total of 2277 Danish patients had a validated ASD diagnosis. Of these, 310 women were identified in the DMBR. Women with ASD had an increased risk of receiving IVF treatment (HR 3.14, 95% CI 2.1 to 4.7, p<0.0001), and a higher proportion of patients received IVF treatment when compared with the reference cohort (10.6% vs 3.2%; p<0.001). Furthermore, patients had more multiple births. Looking at singleton pregnancies (n=519), pre-eclampsia occurred more frequently in patients with ASD during pregnancy (6.7% vs 2.3%; p<0.001). Infants from mothers with ASD were found to have perinatal outcomes comparable to those of infants from the reference group.ConclusionWomen with ASD had an increased risk of and received more IVF treatment than the reference group. The outcome of pregnancy in these patients were generally uneventful, however, we did confirm that pre-eclampsia occurred more frequently.

scholarly journals Adverse perinatal outcomes in 665,244 term and post-term deliveries—a Norwegian population-based study

2020 ◽  
Vol 247 ◽  
pp. 212-218
Author(s):  
Gulim Murzakanova ◽  
Sari Räisänen ◽  
Anne Flem Jacobsen ◽  
Kristina Baker Sole ◽  
Lisa Bjarkø ◽  
...  
Keyword(s):  
Perinatal Outcomes ◽  
Population Based ◽  
Population Based Study ◽  
Norwegian Population ◽  
Adverse Perinatal Outcomes

scholarly journals Asthma during Pregnancy in a Population-Based Study - Pregnancy Complications and Adverse Perinatal Outcomes

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e104755 ◽  
Author(s):  
Gustaf Rejnö ◽  
Cecilia Lundholm ◽  
Tong Gong ◽  
Kjell Larsson ◽  
Sissel Saltvedt ◽  
...  
Keyword(s):  
Pregnancy Complications ◽  
Perinatal Outcomes ◽  
Population Based ◽  
Population Based Study ◽  
Adverse Perinatal Outcomes
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