The First Total Synthesis of Galloyl Tyramine

2009 ◽  
Vol 64 (4) ◽  
pp. 464-466 ◽  
Author(s):  
Nisar Ullah
Keyword(s):  
Total Synthesis ◽  
High Yield ◽  
Reaction Sequence

The first total synthesis of galloyl tyramine, an inhibitor of Pim2 kinase was accomplished in an overall high-yield reaction sequence

scholarly journals The First Total Synthesis of Racemic Hydroxymoloka’iamine

2009 ◽  
Vol 64 (7) ◽  
pp. 879-882 ◽  
Author(s):  
Nisar Ullah
Keyword(s):  
Total Synthesis ◽  
Red Sea ◽  
High Yield ◽  
Reaction Sequence

The first total synthesis of racemic hydroxymoloka’iamine, a new brominated metabolite isolated from Red Sea sponge Pseudoceratna arabica, was achieved in a high-yield reaction sequence.

Towards the Total Synthesis of Schisandrene: Stereoselective Synthesis of the Dibenzocyclooctadiene Lignan Core

Synlett ◽  
2018 ◽  
Vol 29 (07) ◽  
pp. 908-911 ◽  
Author(s):  
K. Babu ◽  
Arramshetti Venkanna ◽  
Borra Poornima ◽  
Bandi Siva ◽  
B. Babu
Keyword(s):  
Total Synthesis ◽  
Stereoselective Synthesis ◽  
Asymmetric Reduction ◽  
Cross Coupling ◽  
Membered Ring ◽  
Stille Reaction ◽  
Reaction Sequence ◽  
Ring Closing Metathesis ◽  
Synthetic Strategy ◽  
First Time

A stereoselective synthesis of the dibenzocyclooctadiene ­lignan core of the natural product schisandrene is described. Starting from readily available gallic acid, the synthetic strategy involves Suzuki–Miyaura cross-coupling, Stille reaction, and ring-closing metathesis (RCM) in the reaction sequence. The required asymmetric center at C-7′ was established by an asymmetric reduction of a keto compound using the Corey–Bakshi–Shibata (CBS) catalyst. In our approach, the eight-membered ring was achieved by RCM for the first time.

scholarly journals Streamlined chemoenzymatic total synthesis of prioritized ganglioside cancer antigens

2018 ◽  
Vol 16 (22) ◽  
pp. 4076-4080 ◽  
Author(s):  
Hai Yu ◽  
Abhishek Santra ◽  
Yanhong Li ◽  
John B. McArthur ◽  
Tamashree Ghosh ◽  
...  
Keyword(s):  
Total Synthesis ◽  
High Yield ◽  
One Pot ◽  
Highly Efficient ◽  
Cancer Antigens

Highly efficient streamlined total synthesis of complex prioritized gangliosides was achieved chemoenzymatically by sequential one-pot multienzyme (OPME) reactions with facile C18 cartridge purification schemes followed by high-yield acylation.

A high yield total synthesis of dl-4-isoavenaciolide

1975 ◽  
Vol 16 (51) ◽  
pp. 4551-4554 ◽  
Author(s):  
R.E. Damon ◽  
R.H. Schlessinger
Keyword(s):  
Total Synthesis ◽  
High Yield

ChemInform Abstract: A HIGH YIELD STEREOSPECIFIC TOTAL SYNTHESIS OF VINCAMINE

1974 ◽  
Vol 5 (31) ◽  
pp. no-no
Author(s):  
J. L. HERRMANN ◽  
R. J. CREGGE ◽  
J. E. RICHMAN ◽  
C. L. SEMMELHACK ◽  
R. H. SCHLESSINGER
Keyword(s):  
Total Synthesis ◽  
High Yield

High yield stereospecific total synthesis of eburnamonine and eburnamine

1976 ◽  
Vol 17 (11) ◽  
pp. 801-804 ◽  
Author(s):  
J.L. Hermann ◽  
G.R. Kierczykowski ◽  
S.E. Normandin ◽  
R.H. Sclessinger
Keyword(s):  
Total Synthesis ◽  
High Yield

scholarly journals Oxidative allylic rearrangement of cycloalkenols: Formal total synthesis of enantiomerically pure trisporic acid B

2011 ◽  
Vol 7 ◽  
pp. 421-425 ◽  
Author(s):  
Silke Dubberke ◽  
Muhammad Abbas ◽  
Bernhard Westermann
Keyword(s):  
Total Synthesis ◽  
Building Block ◽  
Building Blocks ◽  
Allylic Rearrangement ◽  
Reaction Sequence ◽  
Enantiomerically Pure ◽  
Quaternary Stereocenter

Enantiomerically highly enriched unsaturated β-ketoesters bearing a quaternary stereocenter can be utilized as building blocks for the synthesis of natural occurring terpenes, i. a., trisporic acid and its derivatives. An advanced building block has been synthesized in a short reaction sequence, which involves an oxidative allylic rearrangement initiated by pyridinium dichromate (PDC) as the key step.

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