Cysteinyl leukotriene receptor CysLT1as a novel therapeutic target for allergic rhinitis treatment

2008 ◽  
Vol 12 (4) ◽  
pp. 415-423 ◽  
Author(s):  
Hideaki Shirasaki
Keyword(s):  
Allergic Rhinitis ◽  
Therapeutic Target ◽  
Cysteinyl Leukotriene ◽  
Leukotriene Receptor ◽  
Cysteinyl Leukotriene Receptor ◽  
Novel Therapeutic

scholarly journals Montelukast: Pharmacology, Safety, Tolerability and Efficacy

2009 ◽  
Vol 1 ◽  
pp. CMT.S1147 ◽  
Author(s):  
Michael S. Benninger ◽  
Heather Waters
Keyword(s):  
Allergic Rhinitis ◽  
Combination Therapy ◽  
Receptor Antagonist ◽  
Treatment Options ◽  
Comparative Efficacy ◽  
Leukotriene Receptor Antagonist ◽  
Multiple Treatment ◽  
Cysteinyl Leukotriene ◽  
Leukotriene Receptor ◽  
Cysteinyl Leukotriene Receptor

Allergic rhinitis and asthma are common disorders effecting large percentages of the population of Western countries. There are multiple treatment options available for allergic rhinitis and asthma and stepwise approaches to therapy have been recommended. Montelukast is a cysteinyl leukotriene receptor antagonist that has been found to be effective both in the treatment of allergic rhinitis and asthma. This paper will describe the pharmacology, safety, efficacy and tolerability of montelukast. It will examine the comparative efficacy of montelukast to other medications for the treatment of allergic rhinitis and asthma, as well as discuss the recent studies of combination therapy.

scholarly journals Evaluation of oncogenic cysteinyl leukotriene receptor 2 as a therapeutic target for uveal melanoma

2018 ◽  
Vol 37 (2-3) ◽  
pp. 335-345 ◽  
Author(s):  
K. Slater ◽  
P. S. Hoo ◽  
A. M. Buckley ◽  
J. M. Piulats ◽  
A. Villanueva ◽  
...  
Keyword(s):  
Uveal Melanoma ◽  
Therapeutic Target ◽  
Cysteinyl Leukotriene ◽  
Leukotriene Receptor ◽  
Cysteinyl Leukotriene Receptor
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