Effect of Gastrocnemius Strength to be Applicated Low-Dye Taping in Flatfoot with Arch-Recovery Exercise

After a standardized 6-min bicycle ergometer exercise (89% VO2max) lactic acid removal rates were compared during recovery at rest and exercies at 29.7, 45.3, 61.8, and 80.8% VO2max, and twice while the subjects (N = 7) regulated their own recovery exercise. Blood samples were taken after the standardized exercise and every 5 min during the 30-min recovery periods. During the controlled recovery periods lactic acid removal rates were dependent on the intensity of the recovery (Y‣ = 0.103 + 0.218chi - 0.464 X 10(-2)chi2 + 0.252 X 10(-4)chi3). Optimal removal was predicted to occur at 32% VO2max. Removal rates during the self-regulated recoveries were not different (P greater than 0.05), but these removal rates were faster than during recovery at rest and exercise at 61.8 and 80.8% VO2max (P less than 0.01). Removal rates during the self-regulated recovery and recovery at 29.7 and 45.3% VO2max were not different (P greater than 0.05). The subjects were therefore able to remove lactic acid effectively when selecting their own recovery exercise.

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Heart rate recovery, exercise capacity, and mortality risk in male veterans

European Journal of Preventive Cardiology ◽

10.1177/1741826711398432 ◽

2011 ◽

Vol 19 (2) ◽

pp. 177-184 ◽

Cited By ~ 21

Author(s):

Peter Kokkinos ◽

Jonathan Myers ◽

Michael Doumas ◽

Charles Faselis ◽

Andreas Pittaras ◽

...

Keyword(s):

Heart Rate ◽

Exercise Capacity ◽

Mortality Risk ◽

Heart Rate Recovery ◽

Male Veterans ◽

Recovery Exercise

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Regulation of neovascularization by S-glutathionylation via the Wnt5a/sFlt-1 pathway

Biochemical Society Transactions ◽

10.1042/bst20140213 ◽

2014 ◽

Vol 42 (6) ◽

pp. 1665-1670 ◽

Cited By ~ 11

Author(s):

Colin E. Murdoch ◽

Markus M. Bachschmid ◽

Reiko Matsui

Keyword(s):

Actin Polymerization ◽

Network Formation ◽

Nuclear Factor Κb ◽

Capillary Density ◽

Vascular Endothelial ◽

Retinal Blood Vessel ◽

Recovery Exercise ◽

Vessel Development ◽

Cysteine Thiols ◽

Endothelial Growth Factor

S-glutathionylation occurs when reactive oxygen or nitrogen species react with protein-cysteine thiols. Glutaredoxin-1 (Glrx) is a cytosolic enzyme which enzymatically catalyses the reduction in S-glutathionylation, conferring reversible signalling function to proteins with redox-sensitive thiols. Glrx can regulate vascular hypertrophy and inflammation by regulating the activity of nuclear factor κB (NF-κB) and actin polymerization. Vascular endothelial growth factor (VEGF)-induced endothelial cell (EC) migration is inhibited by Glrx overexpression. In mice overexpressing Glrx, blood flow recovery, exercise function and capillary density were significantly attenuated after hindlimb ischaemia (HLI). Wnt5a and soluble Fms-like tyrosine kinase-1 (sFlt-1) were enhanced in the ischaemic-limb muscle and plasma respectively from Glrx transgenic (TG) mice. A Wnt5a/sFlt-1 pathway had been described in myeloid cells controlling retinal blood vessel development. Interestingly, a Wnt5a/sFlt-1 pathway was found also to play a role in EC to inhibit network formation. S-glutathionylation of NF-κB components inhibits its activation. Up-regulated Glrx stimulated the Wnt5a/sFlt-1 pathway through enhancing NF-κB signalling. These studies show a novel role for Glrx in post-ischaemic neovascularization, which could define a potential target for therapy of impaired angiogenesis in pathological conditions including diabetes.

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