scholarly journals Capturing the Patient’s Perspective: a Review of Advances in Natural Language Processing of Health-Related Text

2017 ◽  
Vol 26 (01) ◽  
pp. 214-227 ◽  
Author(s):  
G. Gonzalez-Hernandez ◽  
A. Sarker ◽  
K. O’Connor ◽  
G. Savova

Summary Background: Natural Language Processing (NLP) methods are increasingly being utilized to mine knowledge from unstructured health-related texts. Recent advances in noisy text processing techniques are enabling researchers and medical domain experts to go beyond the information encapsulated in published texts (e.g., clinical trials and systematic reviews) and structured questionnaires, and obtain perspectives from other unstructured sources such as Electronic Health Records (EHRs) and social media posts. Objectives: To review the recently published literature discussing the application of NLP techniques for mining health-related information from EHRs and social media posts. Methods: Literature review included the research published over the last five years based on searches of PubMed, conference proceedings, and the ACM Digital Library, as well as on relevant publications referenced in papers. We particularly focused on the techniques employed on EHRs and social media data. Results: A set of 62 studies involving EHRs and 87 studies involving social media matched our criteria and were included in this paper. We present the purposes of these studies, outline the key NLP contributions, and discuss the general trends observed in the field, the current state of research, and important outstanding problems. Conclusions: Over the recent years, there has been a continuing transition from lexical and rule-based systems to learning-based approaches, because of the growth of annotated data sets and advances in data science. For EHRs, publicly available annotated data is still scarce and this acts as an obstacle to research progress. On the contrary, research on social media mining has seen a rapid growth, particularly because the large amount of unlabeled data available via this resource compensates for the uncertainty inherent to the data. Effective mechanisms to filter out noise and for mapping social media expressions to standard medical concepts are crucial and latent research problems. Shared tasks and other competitive challenges have been driving factors behind the implementation of open systems, and they are likely to play an imperative role in the development of future systems.

2017 ◽  
Vol 26 (01) ◽  
pp. 214-227
Author(s):  
G. Gonzalez-Hernandez ◽  
A. Sarker ◽  
K. O’Connor ◽  
G. Savova

Summary Background: Natural Language Processing (NLP) methods are increasingly being utilized to mine knowledge from unstructured health-related texts. Recent advances in noisy text processing techniques are enabling researchers and medical domain experts to go beyond the information encapsulated in published texts (e.g., clinical trials and systematic reviews) and structured questionnaires, and obtain perspectives from other unstructured sources such as Electronic Health Records (EHRs) and social media posts. Objectives: To review the recently published literature discussing the application of NLP techniques for mining health-related information from EHRs and social media posts. Methods: Literature review included the research published over the last five years based on searches of PubMed, conference proceedings, and the ACM Digital Library, as well as on relevant publications referenced in papers. We particularly focused on the techniques employed on EHRs and social media data. Results: A set of 62 studies involving EHRs and 87 studies involving social media matched our criteria and were included in this paper. We present the purposes of these studies, outline the key NLP contributions, and discuss the general trends observed in the field, the current state of research, and important outstanding problems. Conclusions: Over the recent years, there has been a continuing transition from lexical and rule-based systems to learning-based approaches, because of the growth of annotated data sets and advances in data science. For EHRs, publicly available annotated data is still scarce and this acts as an obstacle to research progress. On the contrary, research on social media mining has seen a rapid growth, particularly because the large amount of unlabeled data available via this resource compensates for the uncertainty inherent to the data. Effective mechanisms to filter out noise and for mapping social media expressions to standard medical concepts are crucial and latent research problems. Shared tasks and other competitive challenges have been driving factors behind the implementation of open systems, and they are likely to play an imperative role in the development of future systems.


2016 ◽  
Vol 25 (01) ◽  
pp. 224-233 ◽  
Author(s):  
N. Elhadad ◽  
D. Demner-Fushman

Summary Objectives: This paper reviews work over the past two years in Natural Language Processing (NLP) applied to clinical and consumer-generated texts. Methods: We included any application or methodological publication that leverages text to facilitate healthcare and address the health-related needs of consumers and populations. Results: Many important developments in clinical text processing, both foundational and task-oriented, were addressed in community-wide evaluations and discussed in corresponding special issues that are referenced in this review. These focused issues and in-depth reviews of several other active research areas, such as pharmacovigilance and summarization, allowed us to discuss in greater depth disease modeling and predictive analytics using clinical texts, and text analysis in social media for healthcare quality assessment, trends towards online interventions based on rapid analysis of health-related posts, and consumer health question answering, among other issues. Conclusions: Our analysis shows that although clinical NLP continues to advance towards practical applications and more NLP methods are used in large-scale live health information applications, more needs to be done to make NLP use in clinical applications a routine widespread reality. Progress in clinical NLP is mirrored by developments in social media text analysis: the research is moving from capturing trends to addressing individual health-related posts, thus showing potential to become a tool for precision medicine and a valuable addition to the standard healthcare quality evaluation tools.


2021 ◽  
Author(s):  
Alberto Mesa Murgado ◽  
Ana Parras Portillo ◽  
Pilar López Úbeda ◽  
Maite Martin ◽  
Alfonso Ureña-López

2021 ◽  
Vol 28 (1) ◽  
pp. e100262
Author(s):  
Mustafa Khanbhai ◽  
Patrick Anyadi ◽  
Joshua Symons ◽  
Kelsey Flott ◽  
Ara Darzi ◽  
...  

ObjectivesUnstructured free-text patient feedback contains rich information, and analysing these data manually would require a lot of personnel resources which are not available in most healthcare organisations.To undertake a systematic review of the literature on the use of natural language processing (NLP) and machine learning (ML) to process and analyse free-text patient experience data.MethodsDatabases were systematically searched to identify articles published between January 2000 and December 2019 examining NLP to analyse free-text patient feedback. Due to the heterogeneous nature of the studies, a narrative synthesis was deemed most appropriate. Data related to the study purpose, corpus, methodology, performance metrics and indicators of quality were recorded.ResultsNineteen articles were included. The majority (80%) of studies applied language analysis techniques on patient feedback from social media sites (unsolicited) followed by structured surveys (solicited). Supervised learning was frequently used (n=9), followed by unsupervised (n=6) and semisupervised (n=3). Comments extracted from social media were analysed using an unsupervised approach, and free-text comments held within structured surveys were analysed using a supervised approach. Reported performance metrics included the precision, recall and F-measure, with support vector machine and Naïve Bayes being the best performing ML classifiers.ConclusionNLP and ML have emerged as an important tool for processing unstructured free text. Both supervised and unsupervised approaches have their role depending on the data source. With the advancement of data analysis tools, these techniques may be useful to healthcare organisations to generate insight from the volumes of unstructured free-text data.


2021 ◽  
Author(s):  
Arash Maghsoudi ◽  
Sara Nowakowski ◽  
Ritwick Agrawal ◽  
Amir Sharafkhaneh ◽  
Sadaf Aram ◽  
...  

BACKGROUND The COVID-19 pandemic has imposed additional stress on population health that may result in a higher incidence of insomnia. In this study, we hypothesized that using natural language processing (NLP) to explore social media would help to identify the mental health condition of the population experiencing insomnia after the outbreak of COVID-19. OBJECTIVE In this study, we hypothesized that using natural language processing (NLP) to explore social media would help to identify the mental health condition of the population experiencing insomnia after the outbreak of COVID-19. METHODS We designed a pre-post retrospective study using public social media content from Twitter. We categorized tweets based on time into two intervals: prepandemic (01/01/2019 to 01/01/2020) and pandemic (01/01/2020 to 01/01/2021). We used NLP to analyze polarity (positive/negative) and intensity of emotions and also users’ tweets psychological states in terms of sadness, anxiety and anger by counting the words related to these categories in each tweet. Additionally, we performed temporal analysis to examine the effect of time on the users’ insomnia experience. RESULTS We extracted 268,803 tweets containing the word insomnia (prepandemic, 123,293 and pandemic, 145,510). The odds of negative tweets (OR, 1.31; 95% CI, 1.29-1.33), anger (OR, 1.19; 95% CI, 1.16-1.21), and anxiety (OR, 1.24; 95% CI: 1.21-1.26) were higher during the pandemic compared to prepandemic. The likelihood of negative tweets after midnight was higher than for other daily intevals, comprising approximately 60% of all negative insomnia-related tweets in 2020 and 2021 collectively. CONCLUSIONS Twitter users shared more negative tweets about insomnia during the pandemic than during the year before. Also, more anger and anxiety-related content were disseminated during the pandemic on the social media platform. Future studies using an NLP framework could assess tweets about other psychological distress, habit changes, weight gain due to inactivity, and the effect of viral infection on sleep.


2021 ◽  
Author(s):  
Abul Hasan ◽  
Mark Levene ◽  
David Weston ◽  
Renate Fromson ◽  
Nicolas Koslover ◽  
...  

BACKGROUND The COVID-19 pandemic has created a pressing need for integrating information from disparate sources, in order to assist decision makers. Social media is important in this respect, however, to make sense of the textual information it provides and be able to automate the processing of large amounts of data, natural language processing methods are needed. Social media posts are often noisy, yet they may provide valuable insights regarding the severity and prevalence of the disease in the population. In particular, machine learning techniques for triage and diagnosis could allow for a better understanding of what social media may offer in this respect. OBJECTIVE This study aims to develop an end-to-end natural language processing pipeline for triage and diagnosis of COVID-19 from patient-authored social media posts, in order to provide researchers and other interested parties with additional information on the symptoms, severity and prevalence of the disease. METHODS The text processing pipeline first extracts COVID-19 symptoms and related concepts such as severity, duration, negations, and body parts from patients’ posts using conditional random fields. An unsupervised rule-based algorithm is then applied to establish relations between concepts in the next step of the pipeline. The extracted concepts and relations are subsequently used to construct two different vector representations of each post. These vectors are applied separately to build support vector machine learning models to triage patients into three categories and diagnose them for COVID-19. RESULTS We report that Macro- and Micro-averaged F_{1\ }scores in the range of 71-96% and 61-87%, respectively, for the triage and diagnosis of COVID-19, when the models are trained on human labelled data. Our experimental results indicate that similar performance can be achieved when the models are trained using predicted labels from concept extraction and rule-based classifiers, thus yielding end-to-end machine learning. Also, we highlight important features uncovered by our diagnostic machine learning models and compare them with the most frequent symptoms revealed in another COVID-19 dataset. In particular, we found that the most important features are not always the most frequent ones. CONCLUSIONS Our preliminary results show that it is possible to automatically triage and diagnose patients for COVID-19 from natural language narratives using a machine learning pipeline, in order to provide additional information on the severity and prevalence of the disease through the eyes of social media.


2021 ◽  
Author(s):  
Vishal Dey ◽  
Peter Krasniak ◽  
Minh Nguyen ◽  
Clara Lee ◽  
Xia Ning

BACKGROUND A new illness can come to public attention through social media before it is medically defined, formally documented, or systematically studied. One example is a condition known as breast implant illness (BII), which has been extensively discussed on social media, although it is vaguely defined in the medical literature. OBJECTIVE The objective of this study is to construct a data analysis pipeline to understand emerging illnesses using social media data and to apply the pipeline to understand the key attributes of BII. METHODS We constructed a pipeline of social media data analysis using natural language processing and topic modeling. Mentions related to signs, symptoms, diseases, disorders, and medical procedures were extracted from social media data using the clinical Text Analysis and Knowledge Extraction System. We mapped the mentions to standard medical concepts and then summarized these mapped concepts as topics using latent Dirichlet allocation. Finally, we applied this pipeline to understand BII from several BII-dedicated social media sites. RESULTS Our pipeline identified topics related to toxicity, cancer, and mental health issues that were highly associated with BII. Our pipeline also showed that cancers, autoimmune disorders, and mental health problems were emerging concerns associated with breast implants, based on social media discussions. Furthermore, the pipeline identified mentions such as rupture, infection, pain, and fatigue as common self-reported issues among the public, as well as concerns about toxicity from silicone implants. CONCLUSIONS Our study could inspire future studies on the suggested symptoms and factors of BII. Our study provides the first analysis and derived knowledge of BII from social media using natural language processing techniques and demonstrates the potential of using social media information to better understand similar emerging illnesses. CLINICALTRIAL


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