FRACTIONATION AND ANALYSIS OF MONKEY PITUITARY GLANDS FOR POSTERIOR LOBE HORMONES
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ABSTRACT Fractionation of monkey pituitary glands gave an oxytocin fraction in low yield which showed a counter-current distribution coefficient equivalent to that obtained with oxytocin from other species. Fractionation and chromatography of monkey vasopressin on carboxymethyl cellulose gave arginine-vasopressin of 60% purity, based on amino acid analysis and specific activity. Counter-current distribution on a small scale gave arginine-vasopressin of 89% purity. Reports by others that monkey pituitary glands contain arginine-vasopressin, based on pharmacological activities, are substantiated by the chemical data presented here.
1966 ◽
Vol 21
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pp. 119-121
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1987 ◽
Vol 5
(2)
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pp. 115-129
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1973 ◽
Vol 7
(4)
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pp. 573-577
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1983 ◽
Vol 262
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pp. 277-284
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1964 ◽
Vol 10
(2)
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pp. 187-198
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1962 ◽
Vol 9
(4)
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pp. 318-322
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1966 ◽
Vol 25
(6)
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pp. 670-675
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1962 ◽
Vol 61
(4)
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pp. 625-627
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