Phenotypic dissection of bone mineral density facilitates the identification of skeletal site specificity on the genetic regulation of bone

2013 ◽  
Author(s):  
P Kemp John ◽  
Medina-Gomez Carolina ◽  
Estrada Karol ◽  
H M Heppe Denise ◽  
M Zillikens Carola ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Genetic Regulation ◽  
Site Specificity ◽  
Mineral Density ◽  
Skeletal Site

Phenotypic dissection of bone mineral density facilitates the identification of skeletal site specificity on the genetic regulation of bone

2013 ◽  
Author(s):  
John P Kemp ◽  
Carolina Medina-Gomez ◽  
Karol Estrada ◽  
Denise Heppe ◽  
Carola Zillikens ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Genetic Regulation ◽  
Site Specificity ◽  
Mineral Density ◽  
Skeletal Site

scholarly journals Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment

PLoS Genetics ◽  
2014 ◽  
Vol 10 (6) ◽  
pp. e1004423 ◽  
Author(s):  
John P. Kemp ◽  
Carolina Medina-Gomez ◽  
Karol Estrada ◽  
Beate St Pourcain ◽  
Denise H. M. Heppe ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mass ◽  
Bone Mineral ◽  
Genetic Regulation ◽  
Site Specificity ◽  
Mineral Density ◽  
Skeletal Site

scholarly journals Skeletal site-dependent response of bone mineral density and quantitative ultrasound parameters following a 12-month dietary intervention using dairy products fortified with calcium and vitamin D: the Postmenopausal Health Study

2006 ◽  
Vol 96 (6) ◽  
pp. 1140-1148 ◽  
Author(s):  
George Moschonis ◽  
Yannis Manios
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Quantitative Ultrasound ◽  
Dairy Products ◽  
The Other ◽  
Mineral Density ◽  
Skeletal Site ◽  
Total Body

The aim of the current study was to examine whether calcium supplementation could prevent bone loss in postmenopausal women or more favourable outcomes could be obtained via the consumption of dairy products fortified with calcium and vitamin D3. For this purpose changes in bone mineral density (BMD) at different skeletal sites, assessed by dual-energy X-ray absorptiometry, as well as in quantitative ultrasound (QUS) parameters of the calcaneus over 12 months were estimated. A population of 101 postmenopausal women (55–65 years old) was randomized into a dairy group (DG: n 39), receiving approximately 1200 mg calcium/d and 7·5 μg vitamin D3/d through fortified dairy products; a calcium-supplemented group (CaG: n 26) provided with a calcium supplement of 600 mg/d; and a control group (CG: n 36). Over the intervention period the DG was found to have more favourable changes in pelvis (P = 0·040), total spine (P < 0·001) and total body BMD (P < 0·001) than the other groups. A significant increase was also observed for DG in lumbar spine BMD (2·0 %; 95 % CI 0·5, 3·5) although it did not differentiate significantly compared to the other groups. No significant differences were observed with respect to the changes in QUS parameters. The current study revealed that recommended intakes of vitamin D3 and calcium via fortified dairy products for 12 months can induce favourable changes in pelvis, total spine and total body BMD in postmenopausal women but not in QUS parameters. No such favourable changes were observed via supplementation of calcium alone.

Skeletal Site Bone Mineral Density Heterogeneity in Women and Men

2001 ◽  
Vol 12 (5) ◽  
pp. 362-365 ◽  
Author(s):  
G. Phillipov ◽  
P. J. Phillips
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Skeletal Site

Predictors of Bone Mineral Density in Aging Healthy Men Varies by Skeletal Site

2002 ◽  
Vol 70 (3) ◽  
pp. 137-145 ◽  
Author(s):  
B.L. Clarke ◽  
P.R. Ebeling ◽  
J.D. Jones ◽  
H.W. Wahner ◽  
W.M. O'Fallon ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Healthy Men ◽  
Skeletal Site

SITE-SPECIFICITY OF BONE MINERAL DENSITY AND MUSCLE STRENGTH IN WOMEN

1998 ◽  
Vol 77 (6) ◽  
pp. 470-476 ◽  
Author(s):  
Mehrsheed Sinaki ◽  
Lorraine A. Fitzpatrick ◽  
Candace K. Ritchie ◽  
Angelo Montesano ◽  
Heinz W. Wahner
Keyword(s):  
Bone Mineral Density ◽  
Muscle Strength ◽  
Bone Mineral ◽  
Site Specificity ◽  
Mineral Density

Genetic regulation of femoral bone mineral density: Complexity of sex effect in chromosome 1 revealed by congenic sublines of mice

Bone ◽  
2007 ◽  
Vol 41 (3) ◽  
pp. 340-345 ◽  
Author(s):  
B. Edderkaoui ◽  
D.J. Baylink ◽  
W.G. Beamer ◽  
K.L. Shultz ◽  
J.E. Wergedal ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Genetic Regulation ◽  
Chromosome 1 ◽  
Femoral Bone ◽  
Mineral Density ◽  
Femoral Bone Mineral Density ◽  
Sex Effect

PREVALENCE OF OSTEOPOROSIS IN WOMEN: VARIATION WITH SKELETAL SITE OF MEASUREMENT OF BONE MINERAL DENSITY

2000 ◽  
Vol 6 (2) ◽  
pp. 127-131 ◽  
Author(s):  
Thomas T. Aoki, MD, FACE ◽  
Eugen O. Grecu, MD, FACE ◽  
Prashante R. Srinivas, MD ◽  
Pamela Prescott, MD ◽  
Mahmoud Benbarka, MD ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Skeletal Site ◽  
Prevalence Of Osteoporosis
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