Investigating effects of novel conjugate drugs for the treatment of osteoporosis

2014 ◽  
Author(s):  
Sally Hu ◽  
Tom Willet ◽  
Robert N Young ◽  
Marc Grynpas
Keyword(s):  
Treatment Of Osteoporosis

Osteoporose und Frakturrisiko beim älteren Sportler: Aktuelle Guidelines

2014 ◽  
Vol 62 (4) ◽  
Keyword(s):  
Fragility Fracture ◽  
Elderly Person ◽  
Vitamin D Supplementation ◽  
Risk Scores ◽  
Human Beings ◽  
Off Label Use ◽  
Risk Of Falling ◽  
Treatment Of Osteoporosis ◽  
Pharmacological Prevention ◽  
Age Related

A Fragility Fracture is nowadays looked upon to be the most important clinical symptom of osteoporosis. The sportive elderly have a limited risk to suffer from this event. Mechanical loading of the skeleton which is associated with most sporty activities prevents age related bone loss. Furthermore, if a fracture happens as a result from sporty activity, the criterion of a fragility fracture is usually not met. Elderly sportsmen who want to be reassured or who are going to restart activity after a break can be offered a fracture risk calculation by means of FRAX. Correct interpretation of the risk scores needs knowledge of the boundary conditions the algorithm is based on. In contrast a DEXA scan is rarely indicated in this situation. Vitamin D Supplementation can generally be adviced for every elderly person in our region, especially for the sportive ones. Sufficient intake of calcium and protein shall be achieved by a healthy diet. Despite of the risk of falling that is usually associated with any sportive activity it may be summarized, that there is less fractures in active people. As long as human beings stay mobile and active, pharmacological prevention or treatment of osteoporosis is rarely indicated. An exeption from this is osteoanabolic treatment of insufficiency and stress fractures. This shall be mentioned here even though it is an “off-label” use of the drugs.

Raloxifene for the prevention and treatment of osteoporosis in post-menopausal women

2000 ◽  
Author(s):  
A Cranney ◽  
V Robinson ◽  
G Guyatt ◽  
N Krolicki ◽  
JD Adachi ◽  
...  
Keyword(s):  
Treatment Of Osteoporosis ◽  
Menopausal Women ◽  
Prevention And Treatment ◽  
Post Menopausal

scholarly journals Combination therapy of anabolic and nonbisphosphonates antiresorptive agents for the treatment of osteoporosis

Medicine ◽  
2017 ◽  
Vol 96 (52) ◽  
pp. e9534 ◽  
Author(s):  
Shenghan Lou ◽  
Lifan Wang ◽  
Yiwen Wang ◽  
Yunduo Jiang ◽  
Jingwei Liu ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Treatment Of Osteoporosis ◽  
Antiresorptive Agents

The contribution of bone densitometry to the diagnosis and treatment of osteoporosis

Public Health ◽  
1997 ◽  
Vol 111 (3) ◽  
pp. 191-194 ◽  
Author(s):  
C.A.C. Coupland ◽  
I. Packham ◽  
A.R. Lyons ◽  
C.E.D. Chilvers ◽  
D.J. Hosking
Keyword(s):  
Bone Densitometry ◽  
Diagnosis And Treatment ◽  
Treatment Of Osteoporosis

scholarly journals Could Strontium Ranelate Have a Synergistic Role in the Treatment of Osteoporosis?

2009 ◽  
Vol 24 (8) ◽  
pp. 1354-1357 ◽  
Author(s):  
Glen M Blake ◽  
Juliet E Compston ◽  
Ignac Fogelman
Keyword(s):  
Strontium Ranelate ◽  
Treatment Of Osteoporosis
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