Combination sclerostin antibody and zoledronic acid treatment outperforms either treatment alone in a mouse model of osteogenesis imperfecta

2015 ◽  
Author(s):  
Craig Munns ◽  
Lauren Peacock ◽  
Kathy Mikulec ◽  
Michaela Kneissel ◽  
Ina Kramer ◽  
...  
Keyword(s):  
Zoledronic Acid ◽  
Mouse Model ◽  
Osteogenesis Imperfecta ◽  
Acid Treatment ◽  
Sclerostin Antibody

Combination sclerostin antibody and zoledronic acid treatment outperforms either treatment alone in a mouse model of osteogenesis imperfecta

Bone ◽  
2017 ◽  
Vol 101 ◽  
pp. 96-103 ◽  
Author(s):  
David G. Little ◽  
Lauren Peacock ◽  
Kathy Mikulec ◽  
Michaela Kneissel ◽  
Ina Kramer ◽  
...  
Keyword(s):  
Zoledronic Acid ◽  
Mouse Model ◽  
Osteogenesis Imperfecta ◽  
Acid Treatment ◽  
Sclerostin Antibody

scholarly journals Low Dose of Bisphosphonate Enhances Sclerostin Antibody-Induced Trabecular Bone Mass Gains in Brtl/+ Osteogenesis Imperfecta Mouse Model

2018 ◽  
Vol 33 (7) ◽  
pp. 1272-1282 ◽  
Author(s):  
Diana Olvera ◽  
Rachel Stolzenfeld ◽  
Joan C Marini ◽  
Michelle S Caird ◽  
Kenneth M Kozloff
Keyword(s):  
Mouse Model ◽  
Bone Mass ◽  
Osteogenesis Imperfecta ◽  
Trabecular Bone ◽  
Low Dose ◽  
Trabecular Bone Mass ◽  
Sclerostin Antibody

Zoledronic Acid Treatment in Children with Osteogenesis Imperfecta

2011 ◽  
Vol 75 (5) ◽  
pp. 346-353 ◽  
Author(s):  
Ilkka Vuorimies ◽  
Sanna Toiviainen-Salo ◽  
Matti Hero ◽  
Outi Mäkitie
Keyword(s):  
Zoledronic Acid ◽  
Osteogenesis Imperfecta ◽  
Acid Treatment

scholarly journals Sclerostin antibody improves skeletal parameters in a Brtl/+ mouse model of osteogenesis imperfecta

2012 ◽  
Vol 28 (1) ◽  
pp. 73-80 ◽  
Author(s):  
Benjamin P Sinder ◽  
Mary M Eddy ◽  
Michael S Ominsky ◽  
Michelle S Caird ◽  
Joan C Marini ◽  
...  
Keyword(s):  
Mouse Model ◽  
Osteogenesis Imperfecta ◽  
Sclerostin Antibody

Tissue level material composition and mechanical properties in Brtl/+ mouse model of Osteogenesis Imperfecta after sclerostin antibody treatment

2015 ◽  
Author(s):  
William R. Lloyd ◽  
Benjamin P. Sinder ◽  
Joseph Salemi ◽  
Michael S. Ominsky ◽  
Joan C. Marini ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Mouse Model ◽  
Osteogenesis Imperfecta ◽  
Tissue Level ◽  
Material Composition ◽  
Antibody Treatment ◽  
Sclerostin Antibody

scholarly journals Rapidly growing Brtl/+ mouse model of osteogenesis imperfecta improves bone mass and strength with sclerostin antibody treatment

Bone ◽  
2015 ◽  
Vol 71 ◽  
pp. 115-123 ◽  
Author(s):  
Benjamin P. Sinder ◽  
Joseph D. Salemi ◽  
Michael S. Ominsky ◽  
Michelle S. Caird ◽  
Joan C. Marini ◽  
...  
Keyword(s):  
Mouse Model ◽  
Bone Mass ◽  
Osteogenesis Imperfecta ◽  
Antibody Treatment ◽  
Sclerostin Antibody
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