Combination treatment of a novel activin receptor IIB ligand trap and zoledronate improves muscle and bone proprieties in a mouse model of osteogenesis imperfecta

2019 ◽  
Author(s):  
Iris Boraschi-Diaz ◽  
Frank Rauch
Keyword(s):  
Mouse Model ◽  
Osteogenesis Imperfecta ◽  
Combination Treatment ◽  
Activin Receptor ◽  
Activin Receptor Iib

scholarly journals Administration of soluble activin receptor 2B increases bone and muscle mass in a mouse model of osteogenesis imperfecta

Bone Research ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Douglas J. DiGirolamo ◽  
Vandana Singhal ◽  
Xiaoli Chang ◽  
Se-Jin Lee ◽  
Emily L. Germain-Lee
Keyword(s):  
Mouse Model ◽  
Osteogenesis Imperfecta ◽  
Muscle Mass ◽  
Activin Receptor

A Soluble Activin Receptor IIB Fails to Prevent Muscle Atrophy in a Mouse Model of Spinal Cord Injury

2016 ◽  
Vol 33 (12) ◽  
pp. 1128-1135 ◽  
Author(s):  
Zachary A. Graham ◽  
Lauren Collier ◽  
Yuanzhen Peng ◽  
Juan C. Saéz ◽  
William A. Bauman ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Mouse Model ◽  
Muscle Atrophy ◽  
Activin Receptor ◽  
Cord Injury ◽  
Activin Receptor Iib

Abnormal type I collagen glycosylation pattern and cross-linking in a cyclophilin B KO mouse model of recessive osteogenesis imperfecta

2013 ◽  
Author(s):  
Wayne Cabral ◽  
Irina Perdivara ◽  
MaryAnn Weis ◽  
Masahiko Terajima ◽  
Angela Blissett ◽  
...  
Keyword(s):  
Mouse Model ◽  
Osteogenesis Imperfecta ◽  
Type I Collagen ◽  
Cross Linking ◽  
Type I ◽  
Glycosylation Pattern ◽  
Cyclophilin B

Combination sclerostin antibody and zoledronic acid treatment outperforms either treatment alone in a mouse model of osteogenesis imperfecta

2015 ◽  
Author(s):  
Craig Munns ◽  
Lauren Peacock ◽  
Kathy Mikulec ◽  
Michaela Kneissel ◽  
Ina Kramer ◽  
...  
Keyword(s):  
Zoledronic Acid ◽  
Mouse Model ◽  
Osteogenesis Imperfecta ◽  
Acid Treatment ◽  
Sclerostin Antibody

O.10 Effect of combined treatment with soluble activin receptor IIB and AAV-U7-mediated dystrophin exon skipping on muscle function in mdx mice

2011 ◽  
Vol 21 (9-10) ◽  
pp. 703
Author(s):  
W.M.H. Hoogaars ◽  
E. Mouisel ◽  
K. Relizani ◽  
A. Pasternack ◽  
C. Hourde ◽  
...  
Keyword(s):  
Muscle Function ◽  
Combined Treatment ◽  
Exon Skipping ◽  
Mdx Mice ◽  
Activin Receptor ◽  
Activin Receptor Iib ◽  
O 10

Bone Marrow Transplantation for Treatment of the Col1a2+/G610C Osteogenesis Imperfecta Mouse Model

2018 ◽  
Vol 104 (4) ◽  
pp. 426-436 ◽  
Author(s):  
Lucinda R. Lee ◽  
Lauren Peacock ◽  
Samantha L. Ginn ◽  
Laurence C. Cantrill ◽  
Tegan L. Cheng ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Mouse Model ◽  
Osteogenesis Imperfecta ◽  
Marrow Transplantation
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