Thyroid autoimmunity and frequency of malignant or suspicious for malignancy thyroid nodule cytology

2017 ◽  
Author(s):  
Athanasios Siolos ◽  
Vasileios Chambidis ◽  
Zoe Efstathiadou ◽  
Thomas Georgiou ◽  
Athanasios Panagiotou ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Thyroid Autoimmunity

Papillary Thyroid Cancer and Coexisting Autoimmune Thyroiditis

2017 ◽  
Vol 49 (11) ◽  
pp. 869-872 ◽  
Author(s):  
Franziska Veit ◽  
Dieter Graf ◽  
Saskia Momberger ◽  
Brigitte Helmich-Kapp ◽  
Ilka Ruschenburg ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Autoimmune Thyroiditis ◽  
Thyroid Autoimmunity ◽  
Nodular Goiter ◽  
Germinal Centers ◽  
Control Group ◽  
Age Group ◽  
Papillary Thyroid ◽  
Thyroid Carcinomas ◽  
Younger Age

AbstractHistological findings often display an association between papillary thyroid carcinomas (PTC) and autoimmune thyroiditis (AIT) and so differ significantly from follicular thyroid carcinomas (FTC). The aim of this interdisciplinary, retrospective study was to evaluate the association of AIT in patients with PTC and FTC and a control group of benign nodular goiters. One hundred thyroidectomies with histologically confirmed differentiated thyroid carcinomas, 67 with PTC and 33 with FTC, were submitted for examination. The two control groups consisted of 60 patients with euthyroid nodular goiter, displaying no signs for malignancy (no surgery) and 100 patients (second control group) with surgery of a benign nodular goiter. Controls were collected to obtain data about the incidence of significantly increased TPOAbs in the first group and of lymphocytic infiltrates (LI) in the second group. High TPOAbs were found in 35% (23/67) of patients with PTC. LI were detected by histology in 48% (32/67) of PTC. Ten patients (10/32) of this group showed the clinical and histological manifestation of a classic AIT with diffuse dense LI as well as diffuse hypoechogeneity in ultrasonography. In 7/32 cases, the histological report described focal dense LI (fAIT) and in 15/32 cases scant scattered LI. AIT and fAIT, together 25% of all PTC (17/67), showed germinal centers and can therefore be characterized as chronic autoimmune thyroiditis. In this group, high TPOAb could be detected in 94% (16/17). Scan scattered LI without germinal centers (15/32) do not represent a fAIT, although TPOAb are high in 47% (7/15). The younger age group (<45 years) showed significantly more often high TPOAbs (p<0.023) in comparison with the age-group older than 60 years. In contrast to PTC, only 4/33 (12%) patients with FTC had high TPOAb levels. We conclude that in contrast to benign euthyroid goiters and to FTC, different degrees of LI are often associated with high TPOAb levels and seem to be significantly increased in PTC, particularly prominent in younger age. There is a high coincidence between LI and high TPOAb levels. In the presence of hypoechoic thyroid nodule, signs of thyroid autoimmunity such as the presence of high TPOAbs, lymphocytic infiltration in cytology, and/or characteristic ultrasonic features, are arguments that might favor the decision for surgery if a cytologically indeterminate thyroid nodule is found and focal autonomy is excluded by szintiscan.

Abstract #603 Malignant Struma Ovarii with a Coexisting Thyroid Nodule: A Case Report

2019 ◽  
Vol 25 ◽  
pp. 310-311
Author(s):  
Safa Ibrahim ◽  
Geeti Sharma ◽  
Biswaraj Tharu ◽  
Manivel Eswaran
Keyword(s):  
Case Report ◽  
Thyroid Nodule ◽  
Struma Ovarii ◽  
Malignant Struma Ovarii

Abstract #1155: Acute Neck Swelling: A Rare Case of Spontaneous Hemorrhage in Thyroid Nodule

2016 ◽  
Vol 22 ◽  
pp. 278
Author(s):  
Anne Bacal ◽  
Nour Batarseh ◽  
Erin Drever ◽  
Tahira Yasmeen
Keyword(s):  
Thyroid Nodule ◽  
Rare Case ◽  
Neck Swelling ◽  
Spontaneous Hemorrhage

Abstract #919: A Hot Thyroid Nodule in an Acromegaly Patient

2016 ◽  
Vol 22 ◽  
pp. 203
Author(s):  
Nandita Sinha ◽  
Michele Yeung ◽  
Emilia Liao
Keyword(s):  
Thyroid Nodule

The Th1/Th2 paradigm in thyroid autoimmunity: the role of CXCR6+ T-cells

2004 ◽  
Vol 112 (S 1) ◽  
Author(s):  
G Aust ◽  
M Kamprad ◽  
D Sittig ◽  
L Becherer ◽  
P Lamesch ◽  
...  
Keyword(s):  
T Cells ◽  
Thyroid Autoimmunity

Pharyngoesophageal (Killian-Jamieson) Diverticulum Mimicking Thyroid Nodule on Ultrasonography: A Case Report

2006 ◽  
Vol 55 (5) ◽  
pp. 447 ◽  
Author(s):  
Ki Hong Kim ◽  
Eun Ju Son ◽  
Eun kyung Kim ◽  
Jin Young Kwak ◽  
Ki Keun Oh
Keyword(s):  
Case Report ◽  
Thyroid Nodule

High-resolution thyroid nodule clinic: analysis of 1674 thyroid nodules

2014 ◽  
Author(s):  
Jose Carlos Fernandez-Garcia ◽  
Carmen Maria Cortes-Salazar ◽  
Isabel Mancha-Doblas ◽  
Francisco Tinahones
Keyword(s):  
High Resolution ◽  
Thyroid Nodule ◽  
Thyroid Nodules
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