Day case radio-iodine for remnant ablation in differentiated thyroid cancer patients is safe and helps reduce bed pressures in a busy tertiary centre hospital

2019 ◽  
Author(s):  
Victoria Rowse ◽  
Shazia Hussain ◽  
Emily Trahair ◽  
William Drake ◽  
Ayesha Siddiqi
Keyword(s):  
Thyroid Cancer ◽  
Cancer Patients ◽  
Differentiated Thyroid Cancer ◽  
Day Case ◽  
Remnant Ablation ◽  
Tertiary Centre ◽  
Centre Hospital

Lowest effective 131I activity for thyroid remnant ablation of differentiated thyroid cancer patients

2015 ◽  
Vol 54 (03) ◽  
pp. 137-143 ◽  
Author(s):  
A.-S. Moldovan ◽  
M. Ruhlmann ◽  
R. Görges ◽  
A. Bockisch ◽  
S. Rosenbaum-Krumme ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Patients ◽  
Differentiated Thyroid Cancer ◽  
Absorbed Dose ◽  
Thyroid Remnant ◽  
Remnant Ablation ◽  
Dose Threshold ◽  
131I Activity ◽  
Pet Ct ◽  
Absorbed Radiation Dose

SummaryAim: A theoretical dosimetry-based model was applied to estimate the lowest effective radioiodine activity for thyroid remnant ablation of low-risk differentiated thyroid cancer patients. Patients, methods: The model is based on the distribution of the absorbed (radiation) dose per administered radioiodine activity and the absorbed dose threshold of 300 Gy for thyroid remnants, the level believed to destroy most thyroid remnants. For this purpose, 124I PET/CT images of 49 thyroid-ectomised patients were retrospectively analysed to measure the distribution of the (average) absorbed doses to thyroid remnant per administered 131I activity. The fraction of thyroid remnants that received at least 300 Gy was determined for standard activities between 0.37 and 5.55 GBq. The lower activity was considered to be equally effective to that obtained with higher activity if the (absolute) fraction difference was below 5%. Results: A total of 62 thyroid remnants were included. The medians and ranges (in parentheses) for the absorbed dose per unit 131I activity were 359 Gy/GBq (34 to 1825 Gy/ GBq). The fractions of thyroid remnants receiving more than 300 Gy at different therapy activities (within parentheses) were 60% (1.11 GBq), 76% (1.85 GBq), 79% (2.22 GBq), and 81–82% for activities between 2.59 and 3.70 GBq. The therapy activity of 1.11 GBq is considerably less effective than that of 1.85 or 2.22 GBq; therapy activities were equally effective in the range between 2.22 to 3.70 GBq. Conclusion: On the basis of the model and the patients' data included, the lowest effective therapy activity appears to be approximately 2.2 GBq to ablate thyroid remnants. The results of this study may help to guide the design of prospective clinical studies.

scholarly journals Radioiodine remnant ablation in low‐risk differentiated thyroid cancer patients who had R0 dissection is an over treatment

2015 ◽  
Vol 4 (7) ◽  
pp. 1031-1038 ◽  
Author(s):  
Chandrasekhar Bal ◽  
Sanjana Ballal ◽  
Ramya Soundararajan ◽  
Saurav Chopra ◽  
Aayushi Garg
Keyword(s):  
Thyroid Cancer ◽  
Cancer Patients ◽  
Differentiated Thyroid Cancer ◽  
Low Risk ◽  
Remnant Ablation ◽  
Radioiodine Remnant Ablation

Evaluation of differentiated thyroid cancer patients according to different scoring systems: a single center experience

2017 ◽  
Author(s):  
Bekir Cakir ◽  
Cevdet Aydin ◽  
Berna Evranos Ogmen ◽  
Ali Abbas Tam ◽  
Sefika Burcak Polat ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Patients ◽  
Differentiated Thyroid Cancer ◽  
Scoring Systems ◽  
Single Center ◽  
Single Center Experience

Impact of age at the diagnosis of radioiodine resistance in differentiated thyroid cancer patients

2019 ◽  
Author(s):  
Clotilde Saie ◽  
Johanna Wassermann ◽  
Elise Mathy ◽  
Sophie Tezenas ◽  
Nathalie Chereau ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Patients ◽  
Differentiated Thyroid Cancer
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