AbstractThe aim of the study was to investigate factors related to the occurrence of
nighttime hypoglycemia after a football tournament in children with type 1
diabetes mellitus. The multicenter study (GoalDiab study) included 189
children and adolescents with type 1 diabetes mellitus, from 11 diabetes
care centers in Poland. Hypoglycemia was defined according to the
International Hypoglycemia Study Group Statement. We analyzed the data of 95
participants with completed protocols with regards to nighttime hypoglycemia
(82% male), aged 11.6 (9.8–14.2) years, diabetes duration
5.0 (2.0–8.0) years. There were 47 episodes of nighttime Level 1
hypoglycemia (≤3.9 mmol/L). Occurrence of clinically
important Level 2 hypoglycemia (<3.0 mmol/L) during
a game period was positively associated with nighttime hypoglycemia
(≤3.9 mmol/L) incident (Odds Ratio=10.7;
95% Confidence Interval: 1.1–100.2; p=0.04). Using
Continuous Glucose Monitoring was negatively associated with the occurrence
of nighttime hypoglycemia (≤3.9 mmol/L) compared
with using glucose meters or Flash Glucose Monitoring (Odds
Ratio=0.31; 95% Confidence Interval: 0.12–0.83;
p=0.02). The occurrence of clinically important hypoglycemia related
to physical activity is associated with the occurrence of hypoglycemia
during the night. Continuous Glucose Monitoring is negatively associated
with nighttime hypoglycemia after a day of competition.