Success rate of adrenal vein sampling: A ten-year experience

2020 ◽  
Author(s):  
Montoro José Ignacio Martínez ◽  
Fuentes Miguel Damas ◽  
Valero Andrea Fernández ◽  
César María José Picón ◽  
Madueño Francisco José Tinahones
Keyword(s):  
Success Rate ◽  
Adrenal Vein ◽  
Adrenal Vein Sampling

scholarly journals Adrenal vein sampling using rapid cortisol assays in primary aldosteronism is useful in centers with low success rates

2011 ◽  
Vol 165 (2) ◽  
pp. 301-306 ◽  
Author(s):  
Matthias J Betz ◽  
Christoph Degenhart ◽  
Evelyn Fischer ◽  
Anna Pallauf ◽  
Volker Brand ◽  
...  
Keyword(s):  
Success Rate ◽  
Primary Aldosteronism ◽  
Femoral Vein ◽  
Tertiary Care ◽  
Control Period ◽  
Retrospective Chart Review ◽  
University Hospital ◽  
Adrenal Vein ◽  
Success Rates ◽  
Adrenal Vein Sampling

ObjectiveAdrenal vein sampling (AVS) is considered the gold standard in the differential diagnosis of primary aldosteronism (PA), but success rates vary between centers. We hypothesized that rapid (intraprocedure) cortisol measurement can improve performance in a center with initially low AVS success rate.DesignWe analyzed 46 patients with confirmed PA studied between 2008 and 2010. Forty-seven PA patients studied between 2004 and 2008 identified by retrospective chart review served as controls. All patients were treated at a single tertiary care university hospital.MethodsStarting in 2008, rapid cortisol assays (RCA) were performed in all patients during the AVS procedure. A cortisol gradient of ≥2.0 between adrenal vein and a femoral vein sample was used as success criterion. Up to two repeat samples were drawn if adrenal vein cortisol was below this threshold.ResultsDuring the control period 26 of 47 AVS were successful (55%). After introduction of RCA, 39 out of 46 AVS (85%) were successful (P=0.003). In 21 of the 46 cases (46%) a resampling was necessary. The increase in overall success was due to an increase in successful right AVS (85 vs 62% before introduction of RCA; P=0.02) and a training effect (P=0.024 for trend).ConclusionRCA during AVS are useful in centers with an initially low AVS success rate.

Rapid Cortisol Assays Improve the Success Rate of Adrenal Vein Sampling for Primary Aldosteronism

2009 ◽  
Vol 249 (2) ◽  
pp. 318-321 ◽  
Author(s):  
Richard J. Auchus ◽  
Christina Michaelis ◽  
Frank H. Wians ◽  
Bart L. Dolmatch ◽  
Shellie C. Josephs ◽  
...  
Keyword(s):  
Success Rate ◽  
Primary Aldosteronism ◽  
Adrenal Vein ◽  
Adrenal Vein Sampling

scholarly journals Abstract No. 236: Rapid Cortisol Assays Increase Success Rate of Adrenal Vein Sampling

2009 ◽  
Vol 20 (2) ◽  
pp. S91
Author(s):  
M.E. Anderson ◽  
C.K. Trimmer ◽  
S.C. Josephs ◽  
B.L. Dolmatch ◽  
R.J. Auchus ◽  
...  
Keyword(s):  
Success Rate ◽  
Adrenal Vein ◽  
Adrenal Vein Sampling ◽  
Increase Success Rate

scholarly journals Intraprocedural Cortisol Measurement Increases Adrenal Vein Sampling Success Rate in Primary Aldosteronism

2011 ◽  
Vol 24 (12) ◽  
pp. 1280-1285 ◽  
Author(s):  
E. Rossi ◽  
G. Regolisti ◽  
F. Perazzoli ◽  
A. Negro ◽  
C. Grasselli ◽  
...  
Keyword(s):  
Success Rate ◽  
Primary Aldosteronism ◽  
Adrenal Vein ◽  
Adrenal Vein Sampling

Improved technical success and radiation safety of adrenal vein sampling using rapid, semi-quantitative point-of-care cortisol measurement

2018 ◽  
Vol 55 (5) ◽  
pp. 588-592 ◽  
Author(s):  
Michael M Page ◽  
Mario Taranto ◽  
Duncan Ramsay ◽  
Greg van Schie ◽  
Paul Glendenning ◽  
...  
Keyword(s):  
Success Rate ◽  
Point Of Care ◽  
Adrenal Vein ◽  
Success Rates ◽  
Technical Success ◽  
Adrenal Vein Sampling ◽  
Measuring Device ◽  
Sampling Studies ◽  
Technical Success Rate ◽  
Sampling Procedures

Objective Primary aldosteronism is a curable cause of hypertension which can be treated surgically or medically depending on the findings of adrenal vein sampling studies. Adrenal vein sampling studies are technically demanding with a high failure rate in many centres. The use of intraprocedural cortisol measurement could improve the success rates of adrenal vein sampling but may be impracticable due to cost and effects on procedural duration. Design Retrospective review of the results of adrenal vein sampling procedures since commencement of point-of-care cortisol measurement using a novel single-use semi-quantitative measuring device for cortisol, the adrenal vein sampling Accuracy Kit. Measurements: Success rate and complications of adrenal vein sampling procedures before and after use of the adrenal vein sampling Accuracy Kit. Routine use of the adrenal vein sampling Accuracy Kit device for intraprocedural measurement of cortisol commenced in 2016. Results Technical success rate of adrenal vein sampling increased from 63% of 99 procedures to 90% of 48 procedures ( P = 0.0007) after implementation of the adrenal vein sampling Accuracy Kit. Failure of right adrenal vein cannulation was the main reason for an unsuccessful study. Radiation dose decreased from 34.2 Gy.cm2 (interquartile range, 15.8–85.9) to 15.7 Gy.cm2 (6.9–47.3) ( P = 0.009). No complications were noted, and implementation costs were minimal. Conclusions Point-of-care cortisol measurement during adrenal vein sampling improved cannulation success rates and reduced radiation exposure. The use of the adrenal vein sampling Accuracy Kit is now standard practice at our centre.

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