scholarly journals Mapping Quantitative Trait Loci Using Naturally Occurring Genetic Variance Among Commercial Inbred Lines of Maize (Zea maysL.)

Genetics ◽  
2005 ◽  
Vol 169 (4) ◽  
pp. 2267-2275 ◽  
Author(s):  
Yuan-Ming Zhang ◽  
Yongcai Mao ◽  
Chongqing Xie ◽  
Howie Smith ◽  
Lang Luo ◽  
...  
Keyword(s):  
Quantitative Trait Loci ◽  
Quantitative Trait ◽  
Genetic Variance ◽  
Inbred Lines ◽  
Naturally Occurring ◽  
Trait Loci

Markers, maps and the detection of trait loci

1996 ◽  
Vol 1996 ◽  
pp. 50-50
Author(s):  
C.S. Haley
Keyword(s):  
Genetic Variation ◽  
Quantitative Trait Loci ◽  
Genetic Markers ◽  
Quantitative Trait ◽  
Coat Colour ◽  
Combined Effects ◽  
Potential Interest ◽  
Naturally Occurring ◽  
Trait Loci ◽  
Modern Breeding

Naturally occurring genetic variation is the basis for differences in performance and appearance between and within different breeds and lines of livestock. In a few instances (e.g. coat colour, polling) the genes (or loci) which control the variation between animals and breeds have a large enough effect to be individually recognisable. For many traits, however, the combined effects of many different genes act together to control quantitative differences between breeds and individuals within breeds (hence such genes are often referred to as quantitative trait loci or QTLs). Thus the dramatic successes of modern breeding result from generations of selection which has produced accumulated changes at a number of different loci. The genome contains up to 100,000 different genes and identifying those which contribute to variation in traits of interest is a difficult task. One first step is to identify regions of the genome containing loci of potential interest through their linkage to genetic markers.

scholarly journals Quantitative trait loci for lifespan of mated Drosophila melanogaster affect both sexes

2002 ◽  
Vol 80 (3) ◽  
pp. 225-230 ◽  
Author(s):  
SARAH G. REIWITCH ◽  
SERGEY V. NUZHDIN
Keyword(s):  
Quantitative Trait Loci ◽  
Quantitative Trait ◽  
Recombinant Inbred Lines ◽  
Inbred Lines ◽  
Specific Effects ◽  
Genome Wide ◽  
Evolution Of Life ◽  
Trait Loci ◽  
Males And Females ◽  
Qtls Mapping

The properties of alleles at quantitative trait loci (QTLs) contributing to variation in lifespan should be described to determine the mechanisms of evolution of life length and to predict its future changes. Previously, we and others conducted genome-wide screens for QTLs that segregate among one panel of recombinant inbred lines (RILs) using a dense molecular marker map. In non-stressful conditions, QTLs effecting the lifespans of virgin females and males were frequently sex specific. In an unrelated panel of RILs, the effects of QTLs in flies maintained in cages with mixed sexes were similar in both sexes. Here, we re-measured the lifespans of the former panel of RILs in cages with mixed sex cohorts. Lifespan declined owing to mating. The amount of decline correlated between sexes within lines. QTLs mapping to the intervals 15A–19C, 50B–57C, 63A–65A, and 96F–99B had similar effects on the lifespans of both males and females. These QTLs have previously been detected in virgin flies surveys and had sex- and/or environment-specific effects.

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