scholarly journals Autologous Bone Marrow Concentrate (BMC) for the Treatment of Osteoarthritis (O.A) of the Knee, Hip, and Shoulder in Former N.F.L. Players

Author(s):  
Meghana Malur
Stem Cells ◽  
2014 ◽  
Vol 33 (1) ◽  
pp. 146-156 ◽  
Author(s):  
Kenneth A. Pettine ◽  
Matthew B. Murphy ◽  
Richard K. Suzuki ◽  
Theodore T. Sand

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Christopher Centeno ◽  
John Pitts ◽  
Hasan Al-Sayegh ◽  
Michael Freeman

Introduction.We investigated the use of autologous bone marrow concentrate (BMC) with and without an adipose graft, for treatment of knee osteoarthritis (OA).Methods.Treatment registry data for patients who underwent BMC procedures with and without an adipose graft were analyzed. Pre- and posttreatment outcomes of interest included the lower extremity functional scale (LEFS), the numerical pain scale (NPS), and a subjective percentage improvement rating. Multivariate analyses were performed to examine the effects of treatment type adjusting for potential confounding factors. The frequency and type of adverse events (AE) were also examined.Results.840 procedures were performed, 616 without and 224 with adipose graft. The mean LEFS score increased by 7.9 and 9.8 in the two groups (out of 80), respectively, and the mean NPS score decreased from 4 to 2.6 and from 4.3 to 3 in the two groups, respectively. AE rates were 6% and 8.9% in the two groups, respectively. Although pre- and posttreatment improvements were statistically significant, the differences between the groups were not.Conclusion.BMC injections for knee OA showed encouraging outcomes and a low rate of AEs. Addition of an adipose graft to the BMC did not provide a detectible benefit over BMC alone.


2015 ◽  
Vol 40 (1) ◽  
pp. 135-140 ◽  
Author(s):  
Kenneth Pettine ◽  
Richard Suzuki ◽  
Theodore Sand ◽  
Matthew Murphy

The Knee ◽  
2013 ◽  
Vol 20 (6) ◽  
pp. 562-569 ◽  
Author(s):  
D. Enea ◽  
S. Cecconi ◽  
S. Calcagno ◽  
A. Busilacchi ◽  
S. Manzotti ◽  
...  

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