scholarly journals SYNAPTIC RESPONSES OF SUPERIOR CERVICAL GANGLION NEURONS OF RATS WITH EXPERIMENTAL DIABETES MELLITUS

2021 ◽  
Vol 67 (1) ◽  
pp. 24-28
Author(s):  
A.O. Nastenko ◽  
◽  
H.E. Purnyn ◽  
S.A. Fedulova ◽  
M.S. Veselovsky ◽  
...  

Excitatory postsynaptic potentials (EPSP) were recorded from the superior cervical ganglion neurons (SCG) in the rats with experimental streptozotocininduced diabetes (ESD). EPSP was inducted by electrical stimulation of the cervical sympathetic trunk. It was founded that the average value of the EPSP time constant decay in the rats with ESD was 15% higher. At the same time, the amplitudes of EPSP of SCG neurons and the hexamethonium blocking effect in the rats with ESD on 30th day after streptozotocin injection didn’t differ significantly from those in control rats. This may indicate specific functional disorders associated as with steady-state elevated blood glucose level in rats as SCG neurons nicotinic cholinergic receptors.

2011 ◽  
Vol 500 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Joanna Wojtkiewicz ◽  
Judyta K. Juranek ◽  
Ireneusz Kowalski ◽  
Marek Bladowski ◽  
Jarosław Całka ◽  
...  

1904 ◽  
Vol 73 (488-496) ◽  
pp. 99-99
Author(s):  
John Newport Langley ◽  
Hugh Kerr Anderson

It is well known that the cervical sympathetic nerve and the chorda tympani have opposite actions upon the blood-vessels of the sub-maxillary gland, the former causing contraction of the vessels, and the latter, dilatation. Evidence has been given by one of us that the chorda tympani if united with the cervical sympathetic, can in time make connection with the nerve cells of the superior cervical ganglion and become in part vaso-constrictor fibres. Our experiments have been directed to determine whether the cervical sympathetic if allowed an opportunity of becoming connected with the peripheral nerve cells in the course of the chorda tympani will in part change their function from vaso-constrictor to vaso-dilator. Two experiments were made on anæsthetised cats, both give similar results, but one was much more conclusive on the point at issue than the other, and here we shall speak of that only. The superior cervical ganglion was excised and the central end of the cervical sympathetic nerve was joined to the peripheral end of the lingual, which contains the chorda tympani fibres. After allowing time for union and regeneration of the nerves, the cervical sympathetic was stimulated; it caused prompt flushing of the sub-maxillary glands, and the effect was repeatedly obtained.


1992 ◽  
Vol 135 (2) ◽  
pp. 210-214 ◽  
Author(s):  
Jennifer I. Luebke ◽  
Forrest F. Weight ◽  
Luis G. Aguayo

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