With the development of RFID technology, we can identify, locate, track and monitor items in supply chain, retail store, and asset management applications. RFID has become a key technology in the Internet of Things. But RFID data can’t be effectively managed by only using traditional data model because they have their own unique characteristics, such as aggregation, location, temporal and history-oriented, which have to be fully considered and integrated into the data model. Therefore, the architecture of RFID spatio-temporal data management is proposed in this paper. We provide a brief overview of RFID technology and highlight a few of the spatio-temporal data management challenges, such as RFID middleware, RFID event processing, In-memory cache.