Letter to the Editor

PEDIATRICS ◽  
1972 ◽  
Vol 49 (4) ◽  
pp. 630-631
Author(s):  
Henry Levison ◽  
Norman Aspin
Keyword(s):  
Cystic Fibrosis ◽  
Disease Process ◽  
Bronchial Tree ◽  
Aerosol Therapy ◽  
Letter To The Editor

Many physicians do not accept the hypothesis put forward in Dr. Chadwick's letter but rather they still accept the statement by the Committee on Therapy regarding the treatment of cystic fibrosis. This document states, "the aim of nebulization therapy in cystic fibrosis is to deposit particles of water or water-containing medication in the bronchial tree at the site of the disease process" and further goes on to state "nebulization or aerosol therapy must not be confused with humidification."

Letter to the Editor

PEDIATRICS ◽  
1969 ◽  
Vol 43 (5) ◽  
pp. 905-906
Author(s):  
Aubrey Milunsky
Keyword(s):  
Cystic Fibrosis ◽  
Bone Marrow ◽  
Clinical Presentation ◽  
Pancreatic Insufficiency ◽  
Chloride Concentration ◽  
Letter To The Editor ◽  
Patient Reported ◽  
Sweat Sample ◽  
Chloride Concentrations

The patient reported in the foregoing letter is of particular interest in view of the recent observations on patients with tnisomy 21 and cystic fibrosis. The multiple possibilities that could explain the clinical presentation have no doubt been considered by the authors. However, the description of "hypoplastic thrombocytopenia" and later pancytopenia in this patient, associated with pancreatic insufficiency, leads to the serious consideration of Shwachman's syndrome (pancreatic insufficiency and bone marrow dysfunction). The wide discrepancy between the sodium and chloride concentrations in the sweat reported in their letter indicates that evaporation of water may have occurred from the sweat sample, leading to an apparently higher sodium and chloride concentration.

scholarly journals Effect of short-term inhalation of warm saline atomised gas on patients with non-cystic fibrosis bronchiectasis

2020 ◽  
Vol 6 (1) ◽  
pp. 00130-2019 ◽  
Author(s):  
Lihong Zhong ◽  
Ying Xiong ◽  
Zeguang Zheng ◽  
Ni Liu ◽  
Jieying Hu ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Pulmonary Function ◽  
Inflammatory Factors ◽  
Aerosol Therapy ◽  
Short Term ◽  
Walk Distance ◽  
Leicester Cough Questionnaire ◽  
Better Than ◽  
Secretion Clearance

ObjectiveSecretion clearance is advocated in non-cystic fibrosis bronchiectasis, but is often neglected in clinical treatment. The present study aimed to investigate the effect of inhaled 0.9% normal saline by ultrasonic nebuliser with warming (UNW) in stable non-cystic fibrosis bronchiectasis patients with purulent sputum.Methods27 stable patients were enrolled in a randomised crossover trial comprising 3 months of daily UNW aerosol therapy compared with 3 months of daily oral expectorant treatment. The outcomes were quality of life (assessed via the Leicester cough questionnaire (LCQ)), sputum characteristics, pulmonary function, 6-min walk distance (6MWD) and acute exacerbation frequency.ResultsCompared with baseline, the sputum viscosity, sputum colour, LCQ score and 6MWD were significantly improved with UNW (p<0.05), and the improvements in sputum colour, LCQ score, 6MWD and inspirational capacity with UNW were significantly better than those achieved via treatment with oral expectorant (p<0.05). There were no significant differences between treatments in pulmonary function, sputum cytology classification and inflammatory factors of sputum.ConclusionUNW aerosol therapy in non-cystic fibrosis bronchiectasis has small yet significant benefits. However, UNW does not improve the degree of inflammation.

Aerosol Therapy in Cystic Fibrosis: DNase, Tobramycin

1994 ◽  
Vol 15 (05) ◽  
pp. 434-438
Author(s):  
Susan Marshall ◽  
Bonnie Ramsey
Keyword(s):  
Cystic Fibrosis ◽  
Aerosol Therapy

scholarly journals 160 Bacterial contamination of nebulizers after aerosol-therapy in cystic fibrosis patients: evaluation of the steam disinfection efficacy

2017 ◽  
Vol 16 ◽  
pp. S107
Author(s):  
P. Leone ◽  
M. Rossitto ◽  
F. Felicetti ◽  
I. Piermarini ◽  
V.T.G. Assanti ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Bacterial Contamination ◽  
Aerosol Therapy

scholarly journals Letter To The Editor: Amylase Isoenzymes in Cystic Fibrosis

1979 ◽  
Vol 13 (9) ◽  
pp. 1077-1077
Author(s):  
Gordon G Forstner ◽  
Geoffrey Davidson
Keyword(s):  
Cystic Fibrosis ◽  
Letter To The Editor ◽  
Amylase Isoenzymes

Letter to the Editor

PEDIATRICS ◽  
1969 ◽  
Vol 44 (5) ◽  
pp. 773-773
Author(s):  
Aubrey Milunsky
Keyword(s):  
Cystic Fibrosis ◽  
Italian Text ◽  
Sweat Test ◽  
Test Results ◽  
The Poor ◽  
Letter To The Editor

I would like to thank Dr. Rovescalli for pointing out the four or five lines in his Italian text on mongolism in which he mentions patients with mongolism and cystic fibrosis. Unfortunately, no evidence for the diagnosis of cystic fibrosis is provided (e.g. sweat test results). The poor reproduction of the adjoining slide of the pancreas leaves the point further unresolved, since in this disorder the pancreas may appear entirely normal on microscopy in the early weeks of life.

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