Hyaline Membrane Disease Treated with Bovine Surfactant

PEDIATRICS ◽  
1983 ◽  
Vol 71 (6) ◽  
pp. 913-917
Author(s):  
J. A. Smyth ◽  
I. L. Metcalfe ◽  
P. Duffty ◽  
F. Possmayer ◽  
M. H. Bryan ◽  
...  

Six preterm infants with severe hyaline membrane disease requiring ventilation were treated, at a median age of 15.5 hours, with a single intratracheal bolus of a bovine surfactant suspension. Arterial oxygenation increased dramatically, and chest radiograms showed improvement after two to four hours. However, a variable degree of deterioration occurred within 24 hours. All of the infants required oxygen therapy for several weeks, and one developed severe bronchopulmonary dysplasia.

Neonatology ◽  
1985 ◽  
Vol 47 (6) ◽  
pp. 317-322 ◽  
Author(s):  
I. Sen ◽  
T. Tulassay ◽  
J. Kiszel ◽  
F. Ruppert ◽  
E. Sulyok ◽  
...  

1983 ◽  
Vol 103 (4) ◽  
pp. 634-637 ◽  
Author(s):  
Philip G. Rhodes ◽  
Glen R. Graves ◽  
Daksha M. Patel ◽  
Susan B. Campbell ◽  
Bernard I. Blumenthal

Author(s):  
Cristina Tomacinschii ◽  
Aliona Cotoman ◽  
Svetlana Sciuca ◽  
Rodica Selevestru ◽  
Olesea Aioani

Neonatology ◽  
1991 ◽  
Vol 60 (3-4) ◽  
pp. 152-162 ◽  
Author(s):  
Stefaan Van Lierde ◽  
Ann Cornelis ◽  
Hugo Devlieger ◽  
Philippe Moerman ◽  
Joseph Lauweryns ◽  
...  

1995 ◽  
Vol 36 (4-6) ◽  
pp. 353-357 ◽  
Author(s):  
P. Lanning ◽  
O. Tammela ◽  
M. Koivisto

Bronchopulmonary dysplasia (BPD) is an important cause of chronic respiratory distress in low birth infants. The radiological incidence and course of BPD were assessed in 100 consecutive low birth weight infants. Chest radiographs were examined on admission, at the ages of 3 days, 7 days, 2 weeks and 4 weeks and at later follow-up until the examinations were normal. Twelve of the children died. The severity and typical radiological abnormalities of BPD were assessed. Among the children alive, there were 26 with BPD (29.5%). The BPD incidence was highest between the age of 2 weeks and 3 months (18–21%) declining to 3.4% at the age of 12 months. Radiological evidence of BPD was already seen at the age of 2 weeks in 16 of the children. Most cases (73%) had their maximum BPD score at the age of 1 to 3 months. The normalisation of the chest radiography occurred predominantly in the age between 3 and 6 months. The most frequent underlying condition in BPD was hyaline membrane disease in 81%.


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