scholarly journals Giant cell tumor of the dorsal vertebrae. Case report

Case reports ◽  
2019 ◽  
Vol 5 (1) ◽  
pp. 46-53
Author(s):  
Lúver Alexi Macías-Jara ◽  
Kelly Palacios-Silva ◽  
Fernando Polit-Zambrano ◽  
Enrique Gagliardo-Cadena ◽  
Betsy Macías-Jara
Keyword(s):  
Case Report ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Surgical Excision ◽  
Tumor Grade ◽  
Posterior Mediastinum ◽  
Cell Tumor ◽  
Thoracic Vertebrae ◽  
High Resolution Computed Tomography ◽  
Giant Cell Tumors

Introduction: Giant cell tumors are rarely observed in the thoracic vertebrae. They appear between the ages of 20 and 50, more often in women. The purpose of this case report is to make known the clinical characteristics, the presentation and the treatment used to solve this pathology.Case presentation: 37-year-old female patient who presented a clinical picture of seven days of dyspnea, cough with white expectoration, high temperature, paraparesis, loss of control in the sphincters and weight loss. High-resolution computed tomography of the thorax showed a right paraspinal mass located in posterior mediastinum at T8-T9 level. Surgical excision of the tumor was decided by right posterolateral thoracotomy at the seventh intercostal space and free surgical margins. The histopathology report described giant cell tumor grade II. The patient did not require chemotherapy and had a satisfactory evolution.Discussion: This case has a non-specific presentation, as it shows evidence of pain, tumor and functional impotence of the involved region. Surgery is the best treatment and consists of tumor excision, leaving wide margins to prevent recurrences.Conclusions: Giant cell tumors involving the lungs and thoracic vertebrae are underdiagnosed due to their nonspecific symptoms and the limited literature currently available.

scholarly journals Giant cell tumor of sixth thoracic vertebrae: case report.

2013 ◽  
Author(s):  
Atef Ben Nsir ◽  
Imed Ben Said ◽  
Mohamed Badri ◽  
Mohamed Boughamoura ◽  
Hafedh Jemel
Keyword(s):  
Case Report ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Thoracic Vertebrae

Giant Cell Tumor of the Distal Phalanx of the Great Toe

2014 ◽  
Vol 7 (3) ◽  
pp. 236-240 ◽  
Author(s):  
Samuel G. Dellenbaugh ◽  
Lee Wilkinson ◽  
Umur Aydogan
Keyword(s):  
Case Report ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Unusual Case ◽  
Distal Phalanx ◽  
Cell Tumor ◽  
Great Toe ◽  
Therapeutic Level ◽  
Giant Cell Tumors ◽  
Recurrent Nature

Giant cell tumors are rarely seen in the foot. They can cause a significant amount of pain and deformity due to their aggressive and recurrent nature. We present the unusual case of a giant cell tumor of the distal phalanx of the hallux in a 39-year-old man. Levels of Evidence: Therapeutic Level IV, Case Report

scholarly journals Case Report: A Rare Huge Giant Cell Tumor of the Proximal Tibia

2021 ◽  
Author(s):  
Bingxin Zheng ◽  
Lingling Sun ◽  
Guojian Qu ◽  
Chongmin Ren ◽  
Peng Yan ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Proximal Tibia ◽  
Cell Tumor ◽  
Borderline Tumor ◽  
Giant Cell Tumors ◽  
Tumors Of Bone ◽  
Patient Prognosis ◽  
Improve Patient

Abstract Background: Giant cell tumor of bone is a common primary borderline bone tumor, while giant cell tumor of bone in the extremities are generally not very large. Because most tumors have already been controlled by some treatments at the time of pain or finding the tumor. Huge giant cell tumors of bone in the limbs are very rare.Case presentation: We describe a case of a huge giant cell tumor of the proximal tibia with 6-year history and not receiving any treatment. It is not until the rupture and bleeding appeared that the patient is referred to the doctor, and amputation is the only treatment.Conclusions: This report suggests that although giant cell tumor of bone is a borderline tumor, early diagnosis and treatment are essential in order to improve patient prognosis.

scholarly journals Giant Cell Tumor of the Femoral Head: A Case Report and Review of the Literature

2021 ◽  
Vol 11 (5) ◽  
Author(s):  
Hany Elbardesy ◽  
G. A. Sheridan ◽  
S. Guerin
Keyword(s):  
Case Report ◽  
Femoral Head ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Hip Arthroplasty ◽  
Pathological Fracture ◽  
Neoadjuvant Treatment ◽  
Bone Neoplasms ◽  
Cell Tumor ◽  
Giant Cell Tumors

Introduction: Giant cell tumors (GCTs) of the bone are uncommon primary bone neoplasms that occur mainly in the epiphysis of long bones. GCT of the femoral head is rarely encountered. Case Report: We report a rare case of GCT of the femoral head in a 20-year-old female. The patient presented with pathological fracture. The patient underwent total hip arthroplasty (THA). The aim of this paper is to present a case study with pathological fracture of the femoral head and to report the results of a literature review. Conclusion: The treatment of choice for GCT of the proximal femur is a hip arthroplasty with either a standard THA for small confined tumors or endoprosthesis insertion for more extensive tumors. Joint preserving procedures have a high revision rate (47.06%). Denosumab has been tried as a neoadjuvant treatment with some success in certain cases. Keywords: Giant cell tumor, pathological fracture, arthroplasty.

Bilateral Mirror-Symmetrical Giant Cell Tumor of the Tendon Sheath in the Foot and Ankle: A Case Report

2021 ◽  
Vol 60 (1) ◽  
pp. 163-166
Author(s):  
Naji S. Madi ◽  
Said Saghieh ◽  
Ahmad Salah Naja ◽  
Rachid K. Haidar
Keyword(s):  
Case Report ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Tendon Sheath ◽  
Cell Tumor ◽  
Foot And Ankle

scholarly journals A Case Report of Giant Cell Tumor of Tendon Sheath Arising from the Wrist.

1998 ◽  
Vol 47 (2) ◽  
pp. 701-703
Author(s):  
Toru Wakioka ◽  
Naoto Sato ◽  
Nobuhiro Tanaka ◽  
Michihisa Zenmyou
Keyword(s):  
Case Report ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Tendon Sheath ◽  
Cell Tumor

Giant Cell Tumor of the Talar Neck

2007 ◽  
Vol 97 (3) ◽  
pp. 225-228 ◽  
Author(s):  
Hakan Selek ◽  
Hamza Özer ◽  
Sacit Turanli ◽  
Özlem Erdem
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Clinical Signs ◽  
Cell Tumor ◽  
Giant Cell Tumors ◽  
Radiographic Appearance ◽  
Aneurysmal Bone Cysts ◽  
Tumors Of Bone ◽  
Brown Tumors ◽  
Small Bones

We describe a patient with a giant cell tumor in the talar head and neck of the left foot who was diagnosed as having osteochondritis dissecans and treated with arthroscopic drilling in this same location 3 years earlier. Giant cell tumors can be confused with several conditions, including giant cell reparative granulomas, brown tumors, and aneurysmal bone cysts. Giant cell tumors of bone typically occur in the epiphysis of long bones, including the distal femur and proximal tibia. They are uncommonly found in the small bones of the foot or ankle, and talar involvement is rare. Despite this rarity, the radiographic appearance and clinical signs of talar lesions should be considered in the differential diagnosis of nontraumatic conditions in the foot. (J Am Podiatr Med Assoc 97(3): 225–228, 2007)

Intramuscular Tenosynovial Giant Cell Tumor Harboring a Novel CSF1-CD96 Fusion Transcript

2021 ◽  
pp. 106689692110498
Author(s):  
Haider Mejbel ◽  
Gene P. Siegal ◽  
Shi Wei
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Gene Rearrangement ◽  
Fusion Transcript ◽  
Cell Tumor ◽  
Molecular Profile ◽  
Small Subset ◽  
Fusion Partner ◽  
Giant Cell Tumors ◽  
Tenosynovial Giant Cell Tumor

Tenosynovial giant cell tumors typically arise in the synovium of joints, bursae, or tendon sheaths. They may occur in an intra- or extra-articular location and can be divided into localized and diffuse types. The neoplastic nature of the lesion has been supported by a recurrent CSF1 gene rearrangement in a small subset of lesional cells, of which the most common fusion partner is COL6A3. Herein, we report a case of intramuscular localized tenosynovial giant cell tumor harboring a novel CSF1-CD96 fusion transcript, thus expanding the molecular profile of this tumor.

scholarly journals Correlation between Campanacci’s radiological classification of giant cell tumor of bone and expression of Cyclin D1 and PCNA

2017 ◽  
Vol 7 (1) ◽  
pp. 47
Author(s):  
Eréndira G. Estrada-Villaseñor ◽  
Hidalgo Bravo Alberto ◽  
C. Bandala ◽  
P. De la Garza-Montano ◽  
Reyes Medina Naxieli ◽  
...  
Keyword(s):  
Cyclin D1 ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Descriptive Study ◽  
Cell Tumor ◽  
Giant Cell Tumors ◽  
Radiological Classification ◽  
Tumors Of Bone ◽  
Made In

Giant cell tumor of bone is considered by his behavior a benign but aggressive neoplasm. The objective of our study was to determine if there is a correlation between the Campanacci’s radiological classification of giant cell tumors of bone and the expression by immunohistochemistry of Cyclin D1 and proliferation cell nuclear antibody (PCNA). A retrospective and descriptive study was made. In total, there were 27 cases. All cases showed Cyclin D1 and PCNA positivity. Rho Spearman for Campanacci and Cyclin D1 expression was 0.06 and for Campanacci and PCNA was 0.418. We conclude that there is a positive correlation between PCNA expression in giant cell tumors of Bone and the Campanacci’s radiological classification II and III, butCyclin D1 expression was no related with radiologic features.

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