PEDIATRIC CRANIOFACIAL DISFIGUREMENT WITH AUTOLOGOUS RIBS BONE GRAFT RECONSTRUCTION

2018 ◽  
Vol 1 (3) ◽  
Author(s):  
Anne Saputra ◽  
Wayan Niryana ◽  
Made Suka Adnyana
Keyword(s):  
Bone Graft ◽  
Skull Base ◽  
Autogenous Bone ◽  
Tumour Resection ◽  
Reconstruction Method ◽  
Functional Requirements ◽  
Skull Base Tumour ◽  
3 Dimensional ◽  
Dimensional Reconstruction ◽  
Autologous Bone Grafts

Pediatric reconstruction of the cranial defect is a challenging task, the standard reconstruction method has been bone grafting. The reconstruction of complex facial defects should satisfy both aesthetic and functional requirements. In the case of large defects, the use of craniofacial prostheses using autogenous bone is the material of choice because of its potential for revascularization and its osteoconductive properties. A 3-year-old patient has facial disfgurement as result from bone defciency following anterior skull base tumour resection. To minimize the associated functional and cosmetic problems, a number  of reconstructive options are available to the surgeon including the use of autogenous and alloplastic implants. A computed tomography (CT) 3-dimensional reconstruction scan showed a large craniofacial defect as residual radical skull base tumour resection. A transcranial approach by a neurosurgeon and plastic surgery was performed to reconstruct the defect using autologous rib bone graft. Six months after the reconstruction surgery, a defect of the craniofacial was narrowing without cranial nerve defcits.Complex reconstructions of extensive defects in craniofacial area can be achieved using autologous bone grafts. They yield reasonable functional and aesthetic outcomes and noticeably improves the qualityof life.

Craniofacial osteotomies to facilitate skull base tumour resection

1986 ◽  
Vol 39 (2) ◽  
pp. 153-160 ◽  
Author(s):  
Ian T. Jackson ◽  
W. Richard Marsh ◽  
Uldis Bite ◽  
T.A.H. Hide
Keyword(s):  
Skull Base ◽  
Tumour Resection ◽  
Skull Base Tumour

scholarly journals Skull base repair following endonasal pituitary and skull base tumour resection – a systematic review

2021 ◽  
Vol 1 ◽  
pp. 100600
Author(s):  
D.Z. Khan ◽  
A.M. Ali ◽  
C.H. Koh ◽  
N.L. Dorward ◽  
J. Grieve ◽  
...  
Keyword(s):  
Systematic Review ◽  
Skull Base ◽  
Tumour Resection ◽  
Skull Base Tumour

scholarly journals Surgical Resection of a Foramen Magnum Meningioma—A Rarely Encountered Skull Base Tumour in Trinidad

2021 ◽  
Author(s):  
Panduranga Seetahal-Maraj
Keyword(s):  
Nervous System ◽  
Skull Base ◽  
General Hospital ◽  
Foramen Magnum ◽  
Tumour Resection ◽  
Surgical Strategies ◽  
Skull Base Tumour ◽  
Excellent Outcome ◽  
San Fernando ◽  
Far Lateral

Tumours of the foramen magnum are infrequent compared to other locations within the neuraxis. Meningiomas are one of the most frequently encountered tumours of the nervous system, but only 1.8 to 3.2% actually originate within the foramen magnum. However, they account for almost 50% of all tumours in this region. We report a case of a large foramen magnum meningioma in a 16-year-old female, the diagnostic difficulty it presents due to its rarity and indolent course, and the surgical strategies employed to manage this case. This was the first performance of a far-lateral craniotomy in San Fernando General Hospital. The use of a staged procedure to facilitate this skull base tumour resection resulted in an excellent outcome.

scholarly journals Skull base repair following endonasal pituitary and skull base tumour resection: a systematic review

Pituitary ◽  
2021 ◽  
Author(s):  
Danyal Z. Khan ◽  
Ahmad M. S. Ali ◽  
Chan Hee Koh ◽  
Neil L. Dorward ◽  
Joan Grieve ◽  
...  
Keyword(s):  
Skull Base ◽  
Tumour Resection ◽  
Skull Base Reconstruction ◽  
Skull Base Tumour ◽  
Randomised Study ◽  
Skull Base Tumours ◽  
Advantages And Disadvantages ◽  
Lumbar Drain ◽  
Meta Analyses ◽  
Repair Techniques

Abstract Purpose Postoperative cerebrospinal fluid rhinorrhoea (CSFR) remains a frequent complication of endonasal approaches to pituitary and skull base tumours. Watertight skull base reconstruction is important in preventing CSFR. We sought to systematically review the current literature of available skull base repair techniques. Methods Pubmed and Embase databases were searched for studies (2000–2020) that (a) reported on the endonasal resection of pituitary and skull base tumours, (b) focussed on skull base repair techniques and/or postoperative CSFR risk factors, and (c) included CSFR data. Roles, advantages and disadvantages of each repair method were detailed. Random-effects meta-analyses were performed where possible. Results 193 studies were included. Repair methods were categorised based on function and anatomical level. There was absolute heterogeneity in repair methods used, with no independent studies sharing the same repair protocol. Techniques most commonly used for low CSFR risk cases were fat grafts, fascia lata grafts and synthetic grafts. For cases with higher CSFR risk, multilayer regimes were utilized with vascularized flaps, gasket sealing and lumbar drains. Lumbar drain use for high CSFR risk cases was supported by a randomised study (Oxford CEBM: Grade B recommendation), but otherwise there was limited high-level evidence. Pooled CSFR incidence by approach was 3.7% (CI 3–4.5%) for transsphenoidal, 9% (CI 7.2–11.3%) for expanded endonasal, and 5.3% (CI 3.4–7%) for studies describing both. Further meaningful meta-analyses of repair methods were not performed due to significant repair protocol heterogeneity. Conclusions Modern reconstructive protocols are heterogeneous and there is limited evidence to suggest the optimal repair technique after pituitary and skull base tumour resection. Further studies are needed to guide practice.

Three-Dimensional Reconstruction Using Stereo Pairs from Serial Thick Sections

1977 ◽  
Vol 35 ◽  
pp. 562-563
Author(s):  
Robert Glaeser ◽  
Thomas Bauer ◽  
David Grano
Keyword(s):  
Three Dimensional ◽  
Dimensional Structure ◽  
Serial Sections ◽  
Thin Sections ◽  
3 Dimensional ◽  
Transmission Electron ◽  
Freeze Dried ◽  
Dimensional Reconstruction ◽  
Stereo Imagery ◽  
Whole Mounts

In transmission electron microscopy, the 3-dimensional structure of an object is usually obtained in one of two ways. For objects which can be included in one specimen, as for example with elements included in freeze- dried whole mounts and examined with a high voltage microscope, stereo pairs can be obtained which exhibit the 3-D structure of the element. For objects which can not be included in one specimen, the 3-D shape is obtained by reconstruction from serial sections. However, without stereo imagery, only detail which remains constant within the thickness of the section can be used in the reconstruction; consequently, the choice is between a low resolution reconstruction using a few thick sections and a better resolution reconstruction using many thin sections, generally a tedious chore. This paper describes an approach to 3-D reconstruction which uses stereo images of serial thick sections to reconstruct an object including detail which changes within the depth of an individual thick section.

Structural preservation and absolute contrast of catalase crystal sections prepared with tannic acid

1983 ◽  
Vol 41 ◽  
pp. 448-449
Author(s):  
C.W. Akey ◽  
M. Szalay ◽  
S.J. Edelstein
Keyword(s):  
Tannic Acid ◽  
Beef Heart ◽  
X Rays ◽  
Screw Axis ◽  
General Applicability ◽  
Thin Sections ◽  
Beef Liver ◽  
3 Dimensional ◽  
Dimensional Reconstruction ◽  
Structural Preservation

Three methods of obtaining 20 Å resolution in sectioned protein crystals have recently been described. They include tannic acid fixation, low temperature embedding and grid sectioning. To be useful for 3-dimensional reconstruction thin sections must possess suitable resolution, structural fidelity and a known contrast. Tannic acid fixation appears to satisfy the above criteria based on studies of crystals of Pseudomonas cytochrome oxidase, orthorhombic beef liver catalase and beef heart F1-ATPase. In order to develop methods with general applicability, we have concentrated our efforts on a trigonal modification of catalase which routinely demonstrated a resolution of 40 Å. The catalase system is particularly useful since a comparison with the structure recently solved with x-rays will permit evaluation of the accuracy of 3-D reconstructions of sectioned crystals.Initially, we re-evaluated the packing of trigonal catalase crystals studied by Longley. Images of the (001) plane are of particular interest since they give a projection down the 31-screw axis in space group P3121. Images obtained by the method of Longley or by tannic acid fixation are negatively contrasted since control experiments with orthorhombic catalase plates yield negatively stained specimens with conditions used for the larger trigonal crystals.

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