Biochemical and Haemopoietic Effects of Aqueous Extract of Gnetum Africanum (Ukazi) on Male and Female Albino Wistar Rats

2018 ◽  
Vol 8 (4) ◽  
pp. 061-065
Author(s):  
F.N OGUWIKE ◽  
◽  
I.C IFEDI ◽  
C.N DIM ◽  
C.P IGWEDIBIA ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Wistar Rats ◽  
Male And Female

scholarly journals Antioxidant Evaluation of the Aqueous Extract of Hulls of Campsiandra laurifolia in Colitis Induced by Acetic Acid in Wistar Rats

2021 ◽  
Vol 41 (02) ◽  
pp. 138-144
Author(s):  
Lucas Petitemberte de Souza ◽  
Henrique Sarubbi Fillmann ◽  
Sandielly Rebeca Benitez da Fonseca ◽  
Marilda da Silva Brasil ◽  
Norma Anair Possa Marroni ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Phenolic Compounds ◽  
Aqueous Extract ◽  
Wistar Rats ◽  
Antioxidant Activities ◽  
Experimental Colitis ◽  
Anal Pressure ◽  
Antioxidant Power ◽  
Significance Level ◽  
Sphincter Anal

AbstractDue to the ethnopharmacological use of Campsiandra laurifolia (Fabaceae), popularly known as Acapurana, to treat wounds and ulcers, associated with the lack of alternative treatments for intestinal inflammations such as ulcerative colitis (UC), the present work sought to characterize its phytochemical and antioxidant activities, and to evaluate remedial action in experimental colitis with acetic acid. Phytochemical analyzes were performed through qualitative and quantitative colorimetric tests of the main secondary metabolites. In the colitis model, 24 male Wistar rats aged ± 60 days old were used, divided into 4 groups: Control (CO) control + aqueous extract of C. laurifolia 50 mg/kg (CO + A50); Colitis (CL); and Colitis + aqueous extract of C. laurifolia 50 mg/kg (CL + A50). Measurement of sphincter anal pressure and histological tests of the large intestine, lipoperoxidation (LPO), enzyme activity of superoxide dismutase (SOD), and levels of glutathione (GSH) were performed. For statistical analysis, the oxidative stress (OS) results were expressed as means ± standard error, adopting a significance level of p < 0.05. The screening indicated the presence of flavonoids, saponins and tannins in the extract, with high levels of phenolic compounds and tannins, and was related to high antioxidant capacity. In the histological analysis, the CL group presented loss of the crypts, edema and inflammatory infiltrate. The use of C. laurifolia extract restructured the crypts, decreased edema and increased sphincter anal pressure, with a decrease in LPO, SOD, and an increase in GSH. It is suggested that the use of C. laurifolia extract reduces OS due to its antioxidant power conferred by the phenolic compounds present in the extract.

scholarly journals Serum pharmacokinetics and coagulation aberration induced by sodium dehydroacetate in male and female Wistar rats

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Yumei Zhang ◽  
Donglai Ying ◽  
Hao Liu ◽  
Zengrong Yu ◽  
Lingling Han ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Male And Female ◽  
Female Wistar Rats

scholarly journals Effect of the aqueous extract of the aerial parts of Monsonia angustifolia E. Mey. Ex A. Rich., on the sexual behaviour of male Wistar rats

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Gerda Fouche ◽  
Anthony J. Afolayan ◽  
Olubunmi A. Wintola ◽  
Tendani E. Khorombi ◽  
Jeremiah Senabe
Keyword(s):  
Aqueous Extract ◽  
Sexual Behaviour ◽  
Wistar Rats ◽  
Aerial Parts ◽  
Male Wistar Rats

Histopathological and biochemical effects of aqueous extract of Tragopogon graminifolius on the liver tissues of Wistar rats fed with high-fat diet

2018 ◽  
Vol 28 (5) ◽  
pp. 1197-1203 ◽  
Author(s):  
Mohammad Mahdi Zangeneh ◽  
Saman Salmani ◽  
Akram Zangeneh ◽  
Reza Khedri ◽  
Mohammad Saeid Zarei
Keyword(s):  
Aqueous Extract ◽  
High Fat Diet ◽  
Wistar Rats ◽  
High Fat ◽  
Biochemical Effects ◽  
Tragopogon Graminifolius ◽  
Liver Tissues

Fixed-consecutive-number performance in male and female Wistar rats

1990 ◽  
Vol 37 (3) ◽  
pp. 255-261 ◽  
Author(s):  
Frans van Haaren ◽  
Annemieke van Hest
Keyword(s):  
Wistar Rats ◽  
Male And Female ◽  
Female Wistar Rats ◽  
Consecutive Number
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