scholarly journals Epidemiology and trend of rabies post exposure prophylaxis at anti rabies clinic of a tertiary care hospital in India

2021 ◽  
pp. 20-24
Author(s):  
Mousumi Datta

Background and Objectives Effective prevention of rabies is possible by vaccination following a rabid animal bite. Objectives of this study was to describe demographics, circumstances of bite and the trend of vaccination over last three years (January 2019-November 2021) in an anti-rabies clinic of a tertiary care hospital. Materials and Methods This was an observational study of prospective design. All animal bite victims who attended the anti rabies clinic (ARC) of the study institution during the study period were invited to participate in the study. Data was collected using a structured schedule on first visit and at 28th day to check for on time compliance to vaccination schedule. On time completion was defined as taking all vaccine doses on due dates. Distribution of variables was shown by frequencies and percentages. Indicators were recorded for three consecutive years. Year wise indicators were compared by chi-square test. Results Data was collected for 293 victims. Median age of bite victims was 41.8 years (range 3-78 years) while 58.7 % respondents were below 45 years of age; 71.3 % victims were male. 82.3 % bites were by dogs; 38 % victims had multiple bites. Post-exposure prophylaxis (PEP) with anti-rabies vaccine (ARV) was initiated within 72 hours for 80 % victims and it was completed on time for 66.2 % victims. Three years trend for PEP indicators did not show a statistically significant difference. Conclusion On time PEP schedule completion was fairly high at the studied ARC. Health seeking for PEP following animal bite was not affected by the corona virus pandemic

Author(s):  
Paramita Sarkar ◽  
Saibendu Kumar Lahiri

Background: Healthcare workers (HCWs) regularly face the risk of exposure to sharp injuries and splashes as an occupational hazard, which presents major risk for acquiring blood-borne infectious agents like human immunodeficiency virus (HIV) which can be minimized by taking post exposure prophylaxis (PEP) measures. There are limited studies from India documenting details of PEP for HIV. This record-based study aimed to determine the occurrence of needle stick injuries (NSIs) and other high-risk occupational exposures to blood and body fluids (BBFs) among HCWs in a tertiary care hospital, Kolkata. We aimed to study details of PEP regimens used among HCWs exposed to HIV.Methods: Hospital record was analyzed from reported incidences of occupational exposures to BBFs occurred during the period of October 2013 to March 2019. Information on self-reported incidence of occupational exposure, and post-exposure management were collected.Results: A total of 105 incidents of occupational exposure were registered during study period. Interns (37, 35.2%) were most frequently exposed, followed by physicians (22, 21.0%) and nurse (21, 20.0%). 88 (83.8%) of the personnel sustained NSIs, and 17 (7.2%) had splashes to skin, mucus membranes. There was no significant difference between subjects with splashes to skin, mucus membranes and needle-stick cases regarding discontinuation of post exposure prophylaxis (PEP) (11.8% versus 19.3%, p<0.548). No cases of sero-conversion were reported.Conclusions: In spite of high incidences of exposures to HIV source, good efficacy of PEP was observed with no sero-conversion. PEP for HIV was well tolerated. Study emphasized the need for creating awareness about timely reporting of incidence.


Sign in / Sign up

Export Citation Format

Share Document