scholarly journals Color standardization and optimization in whole slide imaging

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Takashi Inoue ◽  
Yukako Yagi
2012 ◽  
Vol 35 (2) ◽  
pp. 107-115 ◽  
Author(s):  
Shinsuke Tani ◽  
Yasuhiro Fukunaga ◽  
Saori Shimizu ◽  
Munenori Fukunishi ◽  
Kensuke Ishii ◽  
...  

In the field of whole slide imaging, the imaging device or staining process cause color variations for each slide that affect the result of image analysis made by pathologist. In order to stabilize the analysis, we developed a color standardization method and system as described below: 1) Color standardization method based on RGB imaging and multi spectral sensing, which utilize less band (16 bands) than conventional method (60 bands), 2) High speed spectral sensing module. As a result, we confirmed the following effect: 1) We confirmed the performance improvement of nucleus detection by the color standardization. And we can conduct without training data set which is needed in conventional method, 2) We can get detection performance of H&E component equivalent to conventional method (60 bands). And measurement process is more than 255 times faster.


2014 ◽  
Vol 5 (1) ◽  
pp. 4 ◽  
Author(s):  
PinkyA Bautista ◽  
Noriaki Hashimoto ◽  
Yukako Yagi

PLoS ONE ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. e0184696 ◽  
Author(s):  
Kátia B. Amaral ◽  
Thiago P. Silva ◽  
Felipe F. Dias ◽  
Kássia K. Malta ◽  
Florence M. Rosa ◽  
...  

2008 ◽  
Vol 39 (9) ◽  
pp. 1341-1349 ◽  
Author(s):  
Nicole Velez ◽  
Drazen Jukic ◽  
Jonhan Ho
Keyword(s):  

2012 ◽  
Vol 3 (1) ◽  
pp. 46 ◽  
Author(s):  
Liron Pantanowitz ◽  
Janusz Szymas ◽  
David Wilbur ◽  
Yukako Yagi
Keyword(s):  

2018 ◽  
Vol 9 (4) ◽  
pp. 1601 ◽  
Author(s):  
Shaowei Jiang ◽  
Jun Liao ◽  
Zichao Bian ◽  
Kaikai Guo ◽  
Yongbing Zhang ◽  
...  

2017 ◽  
Vol 142 (3) ◽  
pp. 369-382 ◽  
Author(s):  
Zoya Volynskaya ◽  
Hung Chow ◽  
Andrew Evans ◽  
Alan Wolff ◽  
Cecilia Lagmay-Traya; ◽  
...  

Context.— The critical role of pathology in diagnosis, prognosis, and prediction demands high-quality subspecialty diagnostics that integrates information from multiple laboratories. Objective.— To identify key requirements and to establish a systematic approach to providing high-quality pathology in a health care system that is responsible for services across a large geographic area. Design.— This report focuses on the development of a multisite pathology informatics platform to support high-quality surgical pathology and hematopathology using a sophisticated laboratory information system and whole slide imaging for histology and immunohistochemistry, integrated with ancillary tools, including electron microscopy, flow cytometry, cytogenetics, and molecular diagnostics. Results.— These tools enable patients in numerous geographic locations access to a model of subspecialty pathology that allows reporting of every specimen by the right pathologist at the right time. The use of whole slide imaging for multidisciplinary case conferences enables better communication among members of patient care teams. The system encourages data collection using a discrete data synoptic reporting module, has implemented documentation of quality assurance activities, and allows workload measurement, providing examples of additional benefits that can be gained by this electronic approach to pathology. Conclusion.— This approach builds the foundation for accurate big data collection and high-quality personalized and precision medicine.


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