Chronic thromboembolic pulmonary arterial hypertension: a review of the literature and novel therapeutic approaches

2015 ◽  
Vol 9 (3) ◽  
pp. 351-359
Author(s):  
Emmanuel Androulakis ◽  
Eirini Lioudaki ◽  
Theodoros Christophides ◽  
Mahmood Ahmad ◽  
Hossam Fayed ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Review Of The Literature ◽  
Therapeutic Approaches ◽  
Pulmonary Arterial ◽  
Novel Therapeutic

scholarly journals Novel Therapeutic Approaches of Pulmonary Arterial Hypertension

2019 ◽  
Vol 28 (02) ◽  
pp. 112-117
Author(s):  
Sanjay Tyagi ◽  
Vishal Batra
Keyword(s):  
Nitric Oxide ◽  
Clinical Trials ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Endothelin Receptors ◽  
Pulmonary Vasculature ◽  
Therapeutic Approaches ◽  
Uncommon Disease ◽  
Pulmonary Arterial ◽  
Novel Therapeutic

AbstractPulmonary arterial hypertension (PAH) is an uncommon disease characterized progressive remodeling of pulmonary vasculature. Although treatment for PAH have improved in last two decades but the outcome remains fatal. Currently, the therapies for PAH target three well-established pathways the nitric oxide (NO) pathway, endothelin receptors, and prostanoids. There are multiple potential targets for development of newer drugs in PAH which requires meticulous research and clinical trials.

scholarly journals T6 TRAIL is a potential novel therapeutic target in pulmonary arterial hypertension

Thorax ◽  
2011 ◽  
Vol 66 (Suppl 4) ◽  
pp. A3-A3
Author(s):  
A. G. Hameed ◽  
N. D. Arnold ◽  
J. Pickworth ◽  
J. C. Chamberlain ◽  
C. M. H. Newman ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Therapeutic Target ◽  
Pulmonary Arterial ◽  
Novel Therapeutic

Tumour necrosis factor-related apoptosis-inducing ligand is a novel therapeutic target in pulmonary arterial hypertension

The Lancet ◽  
2013 ◽  
Vol 381 ◽  
pp. S47
Author(s):  
Abdul G Hameed ◽  
Nadine D Arnold ◽  
Janet Chamberlain ◽  
Josephine A Pickworth ◽  
Claudia Paiva ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Tumour Necrosis Factor ◽  
Therapeutic Target ◽  
Tumour Necrosis ◽  
Pulmonary Arterial ◽  
Necrosis Factor ◽  
Novel Therapeutic
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