The association of the circle of Willis anomaly and risk of stroke in patients with carotid artery disease

ABSTRACT The circle of Willis is an important collateral system that maintains perfusion to the stenotic area from the contralateral carotid and basilar artery to the region of reduced brain perfusion. The aim of the present study was to compare the circle of Willis anomaly in patients with unilateral symptomatic and asymptomatic carotid artery disease. Results In this retrospective study, we analyzed 175 patients who presented at our outpatient stroke clinic between January, 2013 and June, 2015 with either unilateral symptomatic or asymptomatic carotid artery disease, and who had had CT angiography imaging performed. Demographic properties, carotid artery stenosis and the anomaly of the circle of Willis was recorded. Conclusion There was no statistically significant difference in patients with symptomatic and asymptomatic carotid artery disease in terms of the anomaly of the circle of Willis.

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Endovascular revascularization of carotid artery stenosis

Medicinski pregled ◽

10.2298/mpns2012351b ◽

2020 ◽

Vol 73 (11-12) ◽

pp. 351-356

Author(s):

Slavko Budinski ◽

Vladimir Manojlovic ◽

Nebojsa Budakov ◽

Nikola Batinic ◽

Milica Pejakovic-Budinski ◽

...

Keyword(s):

Carotid Artery ◽

Carotid Artery Disease ◽

Atherosclerotic Disease ◽

Asymptomatic Carotid ◽

Endovascular Revascularization ◽

Early Results ◽

Disease Therapy ◽

Significant Difference ◽

Male Patients ◽

Artery Disease

Introduction. Endovascular revascularization is a peripheral artery disease therapy used to improve blood flow in blood vessels. The objective of this study was to analyze the types and prevalence of comorbidities in patients with indications for carotid artery revascularization, as well as early results of endovascular carotid artery revascularization in relation to periprocedural complications. Material and Methods. This retrospective study was conducted from October 2014 to October 2019 and included 96 patients. Descriptive and comparative statistical analysis was performed in all patients, male and female, and those with both symptomatic and asymptomatic carotid diseases. Results. The study included 96 patients, of whom 69.8% were male and 30.2% were female. A successful endovascular procedure was performed in 89.6% of patients, while in 10.4% of patients the procedure failed. The distribution of patients by sex, age and the duration of procedure, showed a statistically significant difference (p < 0.05) in the age (p = 0.0003) and duration of the procedure (p = 0.022). The comparison of two groups of patients, with symptomatic and asymptomatic carotid atherosclerotic disease, hyperlipoproteinemia (p = 0.015) showed a statistically significant difference (p < 0.05) between the two groups. Conclusion. Endovascular revascularization has a high success rate in the treatment of atherosclerotic disease of the carotid arteries as well as low periprocedural morbidity and mortality. The analysis of gender-related differences, we concluded that endovascular revascularization lasts significantly longer in female patients, and that the average age is significantly higher in male patients compared to females. We also concluded that hyperlipoproteinemia is a major risk factor for carotid artery disease.

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