scholarly journals Where, when, and how the diagnosis of human visceral leishmaniasis is defined: answers from the Brazilian control program

2019 ◽  
Vol 114 ◽  
Author(s):  
João Gabriel Guimarães Luz ◽  
Amanda Gabriela de Carvalho ◽  
Danilo Bueno Naves ◽  
João Victor Leite Dias ◽  
Cor Jesus Fernandes Fontes
Keyword(s):  
Visceral Leishmaniasis ◽  
Control Program ◽  
Human Visceral Leishmaniasis

scholarly journals Intense transmission of visceral leishmaniasis in a region of northeastern Brazil: a situation analysis after the discontinuance of a zoonosis control program

2021 ◽  
Vol 30 (1) ◽  
Author(s):  
Ranielly Araujo Nogueira ◽  
Maria Gabriela Sampaio Lira ◽  
Sarah Ingrid Pinto Santos ◽  
Renata Mondêgo-Oliveira ◽  
Fábio Henrique Evangelista de Andrade ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Control Program ◽  
Health Department ◽  
Northeastern Brazil ◽  
Canine Leishmaniasis ◽  
Seropositivity Rate ◽  
Human Visceral Leishmaniasis ◽  
Control And Prevention ◽  
Using Data ◽  
Municipal Health

Abstract In São Luís, Maranhão, northeastern Brazil, the notification of visceral leishmaniasis (VL) cases intensified in 1982, showing endemic and epidemic patterns. In this city, the Center for Zoonoses Control (CZC) was an organization in charge of the control and prevention of the disease. However, technical and political reasons have led to a significant decline in the periodicity of its activities. Therefore, in this study we evaluated the epidemiological scenario of human visceral leishmaniasis (HVL) and the prevalence of the disease in dogs after the cessation of the CZC activities, covering the period of 2007 to 2016. The seroprevalence of canine leishmaniasis was determined based on clinical and serological profiles. HVL cases were notified using data provided by the Municipal Health Department of São Luís. A seropositivity rate of 45.8% (p = 0.0001) was found among dogs, 54% (p = 0.374) of which were asymptomatic. As for human cases, there were 415 notifications, with an increase in the incidence of the zoonosis observed during the aforementioned period. Thus, it can be inferred that after the control and surveillance activities were curtailed, there was an increase in the number of seropositive animals in circulation, acting as reservoirs of infection for dogs and humans.

scholarly journals Factors associated with Leishmania chagasi infection in domestic dogs from Teresina, State of Piauí, Brazil

2012 ◽  
Vol 45 (4) ◽  
pp. 480-484 ◽  
Author(s):  
João Pereira da Silva ◽  
Guilherme Loureiro Werneck ◽  
Emanuelle Cardoso Macedo ◽  
Hanny de Carvalho ◽  
Maria do Socorro Pires e Cruz
Keyword(s):  
Visceral Leishmaniasis ◽  
Control Program ◽  
Antibody Test ◽  
Domestic Dogs ◽  
Leishmania Chagasi ◽  
Serological Tests ◽  
Factors Associated ◽  
Human Visceral Leishmaniasis ◽  
History Of ◽  
The City

INTRODUCTION: Many studies have evaluated risk factors for human visceral leishmaniasis, but few have focused on the infection among dogs. The objective of this study was to assess the association between peridomestic socioeconomic and environmental factors and the presence of dogs seropositive for Leishmania chagasi in the City of Teresina, Brazil. METHODS: This case-control study was based on the results of a routine seroepidemiological survey among domestic dogs carried out in 2007. Serological tests were performed by means of indirect immunofluorescence antibody test. All dwellings in which at least one seropositive dog was detected were considered cases, and controls were a random sample of dwellings in which only seronegative dogs were identified. Associations between variables were expressed as odds ratios (OR) and their respective 95% confidence intervals (95%CI) estimated using multivariate logistic regression. RESULTS: Dwellings with a history of dogs removed by the visceral leishmaniasis control program in the last 12 months had five-fold higher odds of having at least one seropositive dog as compared with dwellings having no history of dog removal (OR = 5.19; 95%CI = 3.20-8.42). Dwellings with cats had 58% increased odds of dog infection as compared with those having no cats (OR = 1.58; 95%CI = 1.01-2.47). CONCLUSIONS: Identification of factors associated with canine visceral leishmaniasis might be used for the delimitation of areas of higher risk for human visceral leishmaniasis, since infection in dogs generally precedes the appearance of human cases.

scholarly journals Dispersal of Lutzomyia longipalpis and expansion of canine and human visceral leishmaniasis in São Paulo State, Brazil

Acta Tropica ◽  
2016 ◽  
Vol 164 ◽  
pp. 233-242 ◽  
Author(s):  
Agda Maria Oliveira ◽  
Carolina Portugal Vieira ◽  
Margareth Regina Dibo ◽  
Marluci Monteiro Guirado ◽  
Lilian Aparecida Colebrusco Rodas ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Sao Paulo ◽  
Lutzomyia Longipalpis ◽  
São Paulo ◽  
Paulo State ◽  
Human Visceral Leishmaniasis ◽  
São Paulo State

scholarly journals Trypanosoma cruzi: identification of specific epimastigote antigens by human immune sera

1989 ◽  
Vol 84 (3) ◽  
pp. 309-314 ◽  
Author(s):  
M. G. Morgado ◽  
J. Ivo-dos-Santos ◽  
R. T. Pinho ◽  
E. Argüelles ◽  
J. M. Rezende ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Trypanosoma Cruzi ◽  
Western Blot ◽  
Chagas Disease ◽  
Cross Reactivity ◽  
Cross Reaction ◽  
The Other ◽  
Molecular Weights ◽  
Human Visceral Leishmaniasis ◽  
Human Immune

Soluble antigens from epimastigotes of Trypanosoma cruzi were analyzed by western blot in terms of their reactivity with sera from patients with Chagas' disease. In addition, sera from patients with visceral (AVL) and tegumentar leishmaniasis (ATL) were also tested in order to identify cross-reactivities with Trypanosoma cruzy antigens. Twenty eight polypeptides with molecular weights ranging from 14 kDa to 113 kDa were identified with sera from Chagas' disease patients. An extensive cross-reactivity was observed when sera from human visceral leishmaniasis were used, while only a slight cross-reaction was observed with sera from tegumentar leishmaniasis. On the other hand, 10 polypeptidesspecifically reacting with sera from Chagas' disease patients were identified. Among them, the antigens with molecular weights of 46 kDa and 25 kDa reacted with all sera teste and may be good candidates for specific immunodiagnosis of Chagas' disease.

Interstitial pneumonitis in human visceral leishmaniasis

1989 ◽  
Vol 83 (1) ◽  
pp. 73-76 ◽  
Author(s):  
M.I.S. Duarte ◽  
V.L.R. da Matta ◽  
C.E.P. Corbett ◽  
M.D. Laurenti ◽  
R. Chebabo ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Interstitial Pneumonitis ◽  
Human Visceral Leishmaniasis
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