scholarly journals Does hypericin boost the efficacy of high-power laser? A preliminary experimental study on rats

2014 ◽  
Vol 132 (6) ◽  
pp. 348-352
Author(s):  
Murat Zor ◽  
Serdar Goktas ◽  
Ibrahim Yildirim ◽  
Unal Orhan Zorba ◽  
Seref Basal ◽  
...  
Keyword(s):  
High Power ◽  
Quadriceps Muscle ◽  
Ktp Laser ◽  
High Power Laser ◽  
Power Laser ◽  
Laser Applications ◽  
Symptomatic Benign Prostatic Hyperplasia ◽  
Military Medical Academy ◽  
Medical Academy ◽  
Laser Systems

CONTEXT AND OBJECTIVE: Lasers are widely used in treating symptomatic benign prostatic hyperplasia. In current practice, potassium titanyl phosphate (KTP) lasers are the most common type of laser systems used. The aim here was to evaluate the rapid effect of high-power laser systems after application of hypericin.DESIGN AND SETTING: Experimental animal study conducted in the Department of Urology, Gülhane Military Medical Academy, Ankara, Turkey, in 2012.METHODS: Sixteen rats were randomized into four groups: 120 W KTP laser + hypericin; 120 W KTP laser alone; 80 W KTP laser + hypericin; and 80 W KTP laser alone. Hypericin was given intraperitoneally two hours prior to laser applications. The laser incisions were made through the quadriceps muscle of the rats. The depth and the width of the laser incisions were evaluated histologically and recorded.RESULTS: To standardize the effects of the laser, we used the ratio of depth to width. These new values showed us the depth of the laser application per unit width. The new values acquired were evaluated statistically. Mean depth/width values were 231.6, 173.6, 214.1 and 178.9 in groups 1, 2, 3 and 4, respectively. The most notable result was that higher degrees of tissue penetration were achieved in the groups with hypericin (P < 0.05).CONCLUSIONS: The encouraging results from our preliminary study demonstrated that hypericin may improve the effects of KTP laser applications.

scholarly journals High-power non-perturbative laser delivery diagnostics at the final focus of 100-TW-class laser pulses

2021 ◽  
Vol 9 ◽  
Author(s):  
Fumika Isono ◽  
Jeroen van Tilborg ◽  
Samuel K. Barber ◽  
Joseph Natal ◽  
Curtis Berger ◽  
...  
Keyword(s):  
Low Power ◽  
High Power ◽  
Laser Pulses ◽  
Main Beam ◽  
High Power Laser ◽  
Power Laser ◽  
Laser Applications ◽  
Laser Systems ◽  
Double Surface ◽  
Highly Correlated

Abstract Controlling the delivery of multi-terawatt and petawatt laser pulses to final focus, both in position and angle, is critical to many laser applications such as optical guiding, laser–plasma acceleration, and laser-produced secondary radiation. We present an online, non-destructive laser diagnostic, capable of measuring the transverse position and pointing angle at focus. The diagnostic is based on a unique double-surface-coated wedged-mirror design for the final steering optic in the laser line, producing a witness beam highly correlated with the main beam. By propagating low-power kilohertz pulses to focus, we observed spectra of focus position and pointing angle fluctuations dominated by frequencies below 70 Hz. The setup was also used to characterize the excellent position and pointing angle correlation of the 1 Hz high-power laser pulses to this low-power kilohertz pulse train, opening a promising path to fast non-perturbative feedback concepts even on few-hertz-class high-power laser systems.

Large Mode Area Solid-Core Photonic Bandgap Yb-doped Fiber with Hetero-Structured Cladding for Compact High-Power Laser Systems

2021 ◽  
pp. 1-1
Author(s):  
Olivier Vanvincq ◽  
Andy Cassez ◽  
Remi Habert ◽  
Hicham El Hamzaoui ◽  
Karen Baudelle ◽  
...  
Keyword(s):  
High Power ◽  
Photonic Bandgap ◽  
Solid Core ◽  
High Power Laser ◽  
Power Laser ◽  
Large Mode Area ◽  
Laser Systems ◽  
Mode Area

ALD anti-reflection coatings at 1ω, 2ω, 3ω, and 4ω for high-power ns-laser application

2018 ◽  
Vol 7 (1-2) ◽  
pp. 23-31 ◽  
Author(s):  
Hao Liu ◽  
Lars Jensen ◽  
Ping Ma ◽  
Detlev Ristau
Keyword(s):  
High Power ◽  
High Surface ◽  
Laser System ◽  
Damage Threshold ◽  
Atomic Layer ◽  
Intensity Difference ◽  
High Power Laser ◽  
Power Laser ◽  
Laser Applications ◽  
Laser Induced Damage

AbstractAtomic layer deposition (ALD) facilitates the deposition of coatings with precise thickness, high surface conformity, structural uniformity, and nodular-free structure, which are properties desired in high-power laser coatings. ALD was studied to produce uniform and stable Al2O3and HfO2single layers and was employed to produce anti-reflection coatings for the harmonics (1ω, 2ω, 3ω, and 4ω) of the Nd:YAG laser. In order to qualify the ALD films for high-power laser applications, the band gap energy, absorption, and element content of single layers were characterized. The damage tests of anti-reflection coatings were carried out with a laser system operated at 1ω, 2ω, 3ω, and 4ω, respectively. The damage mechanism was discussed by analyzing the damage morphology and electric field intensity difference. ALD coatings exhibit stable growth rates, low absorption, and rather high laser-induced damage threshold (LIDT). The LIDT is limited by HfO2as the employed high-index material. These properties indicate the high versatility of ALD films for applications in high-power coatings.

scholarly journals High Power Laser Applications to Aerospace

2015 ◽  
Vol 43 (9) ◽  
pp. 611
Author(s):  
Akihiro SASOH ◽  
Toshikazu EBISUZAKI
Keyword(s):  
High Power ◽  
High Power Laser ◽  
Power Laser ◽  
Laser Applications

Broadband amplification at Kr 2 F trimer transition for short-pulse high-power laser applications

2010 ◽  
Author(s):  
Alexey O. Levchenko ◽  
Nikolai N. Ustinovskii ◽  
Vladimir D. Zvorykin
Keyword(s):  
High Power ◽  
Short Pulse ◽  
High Power Laser ◽  
Power Laser ◽  
Laser Applications

scholarly journals Wavefront Shaping by a Small-Aperture Deformable Mirror in the Front Stage for High-Power Laser Systems

2017 ◽  
Vol 7 (4) ◽  
pp. 379 ◽  
Author(s):  
Sensen Li ◽  
Luoxian Zhou ◽  
Can Cui ◽  
Kai Wang ◽  
Xiusheng Yan ◽  
...  
Keyword(s):  
High Power ◽  
Deformable Mirror ◽  
High Power Laser ◽  
Power Laser ◽  
Small Aperture ◽  
Laser Systems ◽  
Wavefront Shaping ◽  
Front Stage

Deformable mirror for high power laser applications

2015 ◽  
Author(s):  
Libor Mrňa ◽  
Martin Sarbort ◽  
Miroslava Hola
Keyword(s):  
High Power ◽  
Deformable Mirror ◽  
High Power Laser ◽  
Power Laser ◽  
Laser Applications
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