scholarly journals ANTI-INFLAMMATORIES FOR DELAYED ONSET MUSCLE SORENESS: SYSTEMATIC REVIEW AND META-ANALYSIS

2021 ◽  
Vol 27 (6) ◽  
pp. 646-654
Author(s):  
Roberto Lohn Nahon ◽  
Jaqueline Santos Silva Lopes ◽  
Anibal Monteiro de Magalhães Neto ◽  
Aloa de Souza Machado ◽  
Luiz Claudio Cameron
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Muscle Soreness ◽  
Meta Analysis ◽  
Delayed Onset Muscle Soreness ◽  
Significant Heterogeneity ◽  
Cochrane Central Register ◽  
Controlled Clinical Trials ◽  
Delayed Onset ◽  
Standard Mean Difference

ABSTRACT Objective: To investigate the effectiveness of pharmacological interventions in the treatment of delayed onset muscle soreness (DOMS). Design: A systematic review and meta-analysis of randomized controlled clinical trials (RCTs). Data sources: The PubMed/MEDLINE, EMBASE, SPORTDiscus, Scielo and Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched for RCTs published prior to August 3, 2020. Eligibility criteria for selecting studies: Studies that 1) used an RCT design; 2) evaluated the effectiveness of steroidal or nonsteroidal anti-inflammatory drugs (NSAIDs) in treating DOMS; and 3) therapeutically used drugs after exercise were included. Results: In total, 26 studies (patients = 934) were eligible for inclusion in the qualitative analysis on the treatment of DOMS. The results of the meta-analysis showed no superiority between the use and non-use of NSAIDs in the improvement of late muscle pain, as no statistically significant differences were verified (21 studies, n= 955; standard mean difference (SMD)= 0.02; 95% confidence interval (CI) −0.58, 0.63; p=0.94; I2=93%). The quality of the synthesized evidence was very low according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) criteria, and there was significant heterogeneity among the included studies. Conclusion: The results demonstrate that NSAIDs are not superior to controls/placebos in treating DOMS. The inclusion of both studies with dose-response protocols and those with exercise protocols may have influenced the results. In addition, the high risk of bias identified reveals that limitations need to be considered when interpreting the results. Level of evidence I; ystematic review of RCT (Randomized and Controlled Clinical Trials).

Reply to comment on “Effect of low-level phototherapy on delayed onset muscle soreness: a systematic review and meta-analysis”

2016 ◽  
Vol 32 (1) ◽  
pp. 249-250
Author(s):  
Fernando Kenji Nampo ◽  
Vinícius Cavalheri ◽  
Solange de Paula Ramos ◽  
Enilton Aparecido Camargo
Keyword(s):  
Systematic Review ◽  
Muscle Soreness ◽  
Meta Analysis ◽  
Delayed Onset Muscle Soreness ◽  
Low Level ◽  
Delayed Onset

scholarly journals Effects of Kinesio Tape on Delayed Onset Muscle Soreness: A Systematic Review and Meta-analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Jianping Lin ◽  
Ming ling Guo ◽  
Hao Wang ◽  
Cheng Lin ◽  
Guiqing Xu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Muscle Strength ◽  
Muscle Soreness ◽  
Randomized Trials ◽  
Meta Analysis ◽  
Delayed Onset Muscle Soreness ◽  
Mean Difference ◽  
Current Evidence ◽  
Kinesio Tape ◽  
Delayed Onset

Background. Kinesio tape (KT) may be useful for the treatment of delayed onset muscle soreness (DOMS), but there has been no systematic review assessing their efficacy. Objectives. We conducted a systematic review and meta-analysis to evaluate the efficacy of KT on DOMS. Methods. We searched seven databases for randomized controlled trials (RCTs) and crossover randomized trials of KT in DOMS, from the earliest date available to December 31, 2019. The primary outcome was muscle soreness. The secondary outcome was muscle strength and serum creatine kinase (CK) level. The risk of bias was evaluated based on the Cochrane criteria. Data were analyzed using RevMan version 5.3.0 software. P values < 0.05 were considered statistically significant. Systematic review registration number is CRD42020157052. Results. Eight trials (six RCTs and two crossover randomized trials) with 289 participants were included. KT use significantly reduced muscle soreness at 48 h (mean difference (MD): -0.67, 95% confidence interval (CI): -1.10 to 0.24, P = 0.002 ) and 72 h postexercise (MD: -0.81, 95% CI: -1.45 to -0.17, P = 0.01 ) but not at 24 h. KT use improved muscle strength at 72 h postexercise (standardized mean difference: 0.35, 95% CI: 0.02 to 0.69, P = 0.04 ) but not at 24 or 48 h. However, the serum CK level at 24, 48, and 72 h postexercise was not better in the KT group relative to the control group. Conclusions. Current evidence suggests that KT might help to alleviate DOMS after strenuous exercise to improve muscle strength. Thus, using KT on the skin for more than 48 hours postexercise, but not for 24 h, appears more effective at relieving pain and improving muscle strength.

scholarly journals Does vibration benefit delayed-onset muscle soreness?: a meta-analysis and systematic review

2018 ◽  
Vol 47 (1) ◽  
pp. 3-18 ◽  
Author(s):  
Xingang Lu ◽  
Yiru Wang ◽  
Jun Lu ◽  
Yanli You ◽  
Lingling Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Analogue Scale ◽  
Muscle Injury ◽  
Muscle Soreness ◽  
Meta Analysis ◽  
Delayed Onset Muscle Soreness ◽  
Controlled Trials ◽  
Delayed Onset ◽  
Randomized Controlled ◽  
Exercise Induced

Objective Delayed-onset muscle soreness (DOMS) is a symptom of exercise-induced muscle injury that is commonly encountered in athletes and fitness enthusiasts. Vibration is being increasingly used to prevent or treat DOMS. We therefore carried out a meta-analysis to evaluate the effectiveness of vibration in patients with DOMS. Method We searched nine databases for randomized controlled trials of vibration in DOMS, from the earliest date available to 30 May 2018. Visual analogue scale (VAS) and creatine kinase (CK) levels were set as outcome measures. Results The review included 10 identified studies with 258 participants. The meta-analysis indicated that vibration significantly improved the VAS at 24, 48, and 72 hours after exercise, and significantly improved CK levels at 24 and 48 hours, but not at 72 hours. Conclusion Vibration is a beneficial and useful form of physiotherapy for alleviating DOMS. However, further studies are needed to clarify the role and mechanism of vibration in DOMS.

Effect of low-level phototherapy on delayed onset muscle soreness: a systematic review and meta-analysis

2015 ◽  
Vol 31 (1) ◽  
pp. 165-177 ◽  
Author(s):  
Fernando Kenji Nampo ◽  
Vinícius Cavalheri ◽  
Solange de Paula Ramos ◽  
Enilton Aparecido Camargo
Keyword(s):  
Systematic Review ◽  
Muscle Soreness ◽  
Meta Analysis ◽  
Delayed Onset Muscle Soreness ◽  
Low Level ◽  
Delayed Onset
Sign in / Sign up

Export Citation Format

Share Document