scholarly journals Abnormally increased iron concentration in basal ganglia in Shy-Drager syndrome MR imaging and autonomic study: RM imagem e estudo autonômico

1991 ◽  
Vol 49 (3) ◽  
pp. 342-347 ◽  
Author(s):  
Jayme A. Maciel Jr. ◽  
Cristiane M. da Rocha ◽  
Sandra Cabelho ◽  
Mario G. Pradal
Keyword(s):  
Basal Ganglia ◽  
Mr Imaging ◽  
Laboratory Tests ◽  
Autonomic Failure ◽  
Iron Concentration ◽  
Pure Autonomic Failure ◽  
Functional Evaluation ◽  
High Field Strength ◽  
Syndrome Diagnosis ◽  
Early Case

Report of an early case of Shy-Drager syndrome in a 67 year-old woman patient. Autonomic failure was diagnosed by functional evaluation as well as laboratory tests. MR imaging disclosed a prominent putamina hypodensity in T2-weighted images at high field strength due to iron increased depositing in this basal ganglia. MR imaging evidences confirm Shy-Drager syndrome diagnosis, and contributes for differential diagnosis of idiopathic hypotension (pure autonomic failure) in special in SDS early cases.

Efficiency of droxydopa in pure autonomic failure

2010 ◽  
Vol 41 (01) ◽  
Author(s):  
M Knosalla ◽  
CA Haensch ◽  
J Wehe ◽  
H Lerch ◽  
J Weis ◽  
...  
Keyword(s):  
Autonomic Failure ◽  
Pure Autonomic Failure

Assessment of Ploy Dopamine Coated Fe3O4 Nanoparticles for Melanoma (B16-F10 and A-375) Cells Detection

2020 ◽  
Vol 20 (16) ◽  
pp. 1918-1926
Author(s):  
Fahimeh H. Beigi ◽  
Soheil Fatahian ◽  
Sogand Shahbazi-Gahrouei ◽  
Daryoush Shahbazi-Gahrouei ◽  
Amin Farzadniya
Keyword(s):  
Mr Imaging ◽  
Mtt Assay ◽  
Fe3o4 Nanoparticles ◽  
Normal Skin ◽  
Iron Concentration ◽  
Positive Effects ◽  
Skin Cells ◽  
Melanoma B16 ◽  
Co Precipitation

Objective: Polydopamine coated iron oxide nanoparticles (Fe3O4@PDA NPs) were synthesized, characterized, and their MR imaging contrast agents and photothermal potency were evaluated on melanoma (B16-F10 and A-375) cells and normal skin cells. To this end, MTT assay, Fe concentration, and MR imaging of both coated and uncoated NPs were assessed in C57BL/6 mice. Methods: Fe3O4 nanoparticles were synthesized using co-precipitation, and coated with polydopamine. The cytotoxicity of Fe3O4 and Fe3O4@PDA NPs on melanoma cells, with different concentrations, were obtained using MTT assay. MR images and Fe concentrations of nanoprobe and nanoparticles were evaluated under in vivo conditions. Results: Findings indicated that uncoated Fe3O4 showed the highest toxicity in animal (B16-F10) cells at 450μg/ml after 72h, while the highest toxicity in human (A-375) cells were observed at 350μg/ml. These nanoparticles did not reveal any cytotoxicity to normal skin cells, despite having some toxicity features in A-375 cells. MR image signals in the tumor were low compared with other tissues. The iron concentration in the tumor was higher than that of other organs. Conclusion: It is concluded that the cytotoxicity of Fe3O4@PDA was found to be significantly lower than uncoated nanoparticles (p <0.001), which allows some positive effects on reducing toxicity. The prepared nanoprobe may be used as a contrast agent in MR imaging.

Skin nerve misfolded α-synuclein in pure autonomic failure and Parkinson disease

2015 ◽  
Vol 79 (2) ◽  
pp. 306-316 ◽  
Author(s):  
Vincenzo Donadio ◽  
Alex Incensi ◽  
Cristina Piccinini ◽  
Pietro Cortelli ◽  
Maria Pia Giannoccaro ◽  
...  
Keyword(s):  
Parkinson Disease ◽  
Autonomic Failure ◽  
Pure Autonomic Failure

DISTRIBUTION OP LEWY BODIES IN PURE AUTONOMIC FAILURE

1996 ◽  
Vol 55 (5) ◽  
pp. 633
Author(s):  
K. Hague ◽  
S. Caro ◽  
H. Kaufmann ◽  
P. Lento ◽  
S. Morgello
Keyword(s):  
Autonomic Failure ◽  
Lewy Bodies ◽  
Pure Autonomic Failure

Pure autonomic failure and the differential diagnosis of autonomic peripheral neuropathies

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Alejandra González-Duarte ◽  
Aditi Varma-Doyle ◽  
Roy Freeman
Keyword(s):  
Differential Diagnosis ◽  
Autonomic Failure ◽  
Pure Autonomic Failure ◽  
Peripheral Neuropathies

scholarly journals Hormonal and cardiovascular reflex assessment in a female patient with pure autonomic failure

2000 ◽  
Vol 75 (3) ◽  
Author(s):  
Heno Ferreira Lopes ◽  
Fernanda Marciano Consolim-Colombo ◽  
Denise Hachul ◽  
Maria Elisa do Amaral Carvalho ◽  
Fúlvio Pileggi ◽  
...  
Keyword(s):  
Female Patient ◽  
Autonomic Failure ◽  
Pure Autonomic Failure ◽  
Cardiovascular Reflex
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