scholarly journals Antibody response to heat-inactivated hepatitis B vaccine (CLB-3mg) in hemodialysis patients and occupational risk personnel: a one year follow-up

1988 ◽  
Vol 30 (1) ◽  
pp. 11-16
Author(s):  
C. F. T. Yoshida ◽  
C. Takahashi ◽  
L. A. C. Mercadante ◽  
I. F. Camargo ◽  
H. G. Schatzmayr
Keyword(s):  
Immune Response ◽  
Hepatitis B ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccine ◽  
Occupational Risk ◽  
Immunization Schedule ◽  
One Year ◽  
Sample Ratio ◽  
Healthy Persons

Immune response against hepatitis B vaccine (CLB 3mg) was evaluated in 59 hemodialysis patients and 20 occupational risk personnel. Seroconversion was induced in 52.5% and 70.0% respectively. Twelve months after the first dose, 37.5% of patients and 60.0% of occupational risk personnel had detectable anti-HBs level. Antibody level was expressed in sample ratio units (SRU). Considering only the responders, in the patients group 38.7% had a low anti-HBs response (2.1-9.9 SRU) 32.3% a medium response (10-99.9 SRU) and 29.0% a high response (>100 SRU) while in occupational risk personnel these values were 14.3%, 64.3% and 21.4% respectively. The authors suggest the use of HBV vaccines with more elevated HBsAg concentration or a reinforced immunization schedule to improve the anti-HBs response not only for patients but also for healthy persons.

scholarly journals A new adjuvant improves the immune response to hepatitis B vaccine in hemodialysis patients

2008 ◽  
Vol 73 (7) ◽  
pp. 856-862 ◽  
Author(s):  
N.C.T. Kong ◽  
J. Beran ◽  
S.A. Kee ◽  
J.L. Miguel ◽  
C. Sánchez ◽  
...  
Keyword(s):  
Immune Response ◽  
Hepatitis B ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccine

Immunogenicity of a Recombinant Hepatitis B Vaccine in Hemodialysis Patients: A Two-Year Follow-Up

Nephron ◽  
1992 ◽  
Vol 61 (3) ◽  
pp. 352-353 ◽  
Author(s):  
D. Docci ◽  
P.A. Cipolloni ◽  
S. Mengozzi ◽  
L. Baldrati ◽  
C. Capponcini ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccine ◽  
Recombinant Hepatitis

Immune Response to a Recombinant Hepatitis B Vaccine in Hemodialysis Patients

1990 ◽  
Vol 13 (7) ◽  
pp. 451-453 ◽  
Author(s):  
D. Docci ◽  
P.A. Cipolloni ◽  
L. Baldrati ◽  
C. Capponcini ◽  
F. Turci ◽  
...  
Keyword(s):  
Immune Response ◽  
Hepatitis B ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccine ◽  
Recombinant Hepatitis

Immune Response to Hepatitis B Vaccine in Hemodialysis Patients

Nephron ◽  
1987 ◽  
Vol 45 (3) ◽  
pp. 216-218 ◽  
Author(s):  
J.A. van Geelen ◽  
S.W. Schalm ◽  
E.M. de Visser ◽  
R.A. Heijtink
Keyword(s):  
Immune Response ◽  
Hepatitis B ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccine

scholarly journals An investigation of the efficacy on hepatitis B vaccination in hemodialysis patients in Ardabil, Iran

2018 ◽  
Vol 8 (1) ◽  
pp. 6-10
Author(s):  
Susan Mohammadi Kebar ◽  
Saeed Hoseininia ◽  
Yousef Mohammadi Kebar ◽  
Mohammad Broumand
Keyword(s):  
Immune Response ◽  
Hepatitis B ◽  
Poor Response ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccine ◽  
Hepatitis B Vaccination ◽  
Double Dose ◽  
Serological Markers ◽  
The Past ◽  
Lower Immune Response

Introduction: Hemodialysis patients usually demonstrate lower immune response to hepatitis B vaccine compared to non-uremic population. Objectives: The present study aimed to determine the level of response to hepatitis B vaccination in patients under hemodialysis. Patients and Methods: This study was conducted on 172 live patients receiving hemodialysis in the dialysis department of Buali hospital in Ardabil, Iran (2015). To analyze their response to the vaccine, their vaccination titers were investigated. Before vaccination, the serological markers of hepatitis B and C were checked in all of the patients. Those for whom HBsAg and HBsAb results were negative and had not received the vaccinein the past entered the study. The patients received a double dose of hepatitis B vaccine at 0, 1, and 6 months after the beginning of dialysis. The response to the vaccine was investigated by measuring the level of patients’ hepatitis B antibody one month after receiving the last dose of the vaccine. Results: Seventy patients (40% of the total) displayed a proper immune response to the vaccine, 34 patients (19.8%) were without, and 68 patients (39.5%) were identified to have poor response. The results of Pearson’s correlation test indicated that there is a negative correlation between the patients’ age and their response to the vaccine. Conclusion: The results of this study indicated that higher age is one of the factors that reduce the effectiveness of hepatitis B vaccine in hemodialysis patients.

scholarly journals Successful vaccination with intradermal hepatitis B vaccine in hemodialysis patients previously nonresponsive to intramuscular hepatitis B vaccine.

1995 ◽  
Vol 5 (11) ◽  
pp. 1930-1934
Author(s):  
N M Waite ◽  
L G Thomson ◽  
M B Goldstein
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Preliminary Data ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Hepatitis B Vaccine ◽  
B Virus ◽  
Lost To Follow Up

Seventy-seven chronic hemodialysis patients were vaccinated against hepatitis B virus with an intramuscular (im) hepatitis B vaccine (HBV), 40 micrograms at 0, 1, 2, and 6 months. Fifty-seven patients (74%) developed antibodies (anti-HBs). The im-responsive patients were significantly younger than the nonresponsive patients (P < 0.05). Nineteen of the 20 im nonresponders received HBV intradermally (id), 5 micrograms every 2 wk until anti-HBs developed; the 20th patient died before receiving the id vaccine. Three patients were lost to follow-up. Fifteen (94%) of the 16 developed anti-HBs after 5.2 +/- 4.7 months. The peak anti-HBs titers were 726 +/- 426 (im) and 211 +/- 260 (id) IU/L (P < 0.05). Twelve (21%) of the 57 im-responsive patients and 8 (53%) of the 15 id-responsive patients had anti-HBs less than 20 IU/L at 18 and 8 months postvaccination, respectively (P < 0.05). Further preliminary data indicate that more prolonged id vaccination can increase both the titer and the duration of anti-HBs in im-nonresponsive patients.

scholarly journals Immune response to the hepatitis B vaccine among HIV-infected adults in Uganda

Vaccine ◽  
2021 ◽  
Vol 39 (8) ◽  
pp. 1265-1271
Author(s):  
E. Seremba ◽  
P. Ocama ◽  
R. Ssekitoleko ◽  
H. Mayanja-Kizza ◽  
S.V. Adams ◽  
...  
Keyword(s):  
Immune Response ◽  
Hepatitis B ◽  
Hepatitis B Vaccine
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